公开(公告)号：US11077234B2

公开(公告)日：2021-08-03

申请号：US15938417

申请日：2018-03-28

Applicant: Allied Bioscience, Inc.

Inventor： Craig Grossman ,  Gavri Grossman ,  Daniel Moros ,  Misagh Alipour ,  Jie Fang

IPC: A61L29/16 ,  A01N55/00 ,  A61L29/02 ,  A61L29/08 ,  A61L29/06 ,  A61L31/08 ,  A61L31/16

Abstract: The present disclosure provides antimicrobial coating compositions that are used to form residual antimicrobial coatings on medical implements and medical devices including the components of medical equipment such as CPAP/BiPAP machines. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N, a titanium (IV) species, a 1,2-diol, an α-hydroxy acid, β-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent, and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

公开(公告)号：US20180280582A1

公开(公告)日：2018-10-04

申请号：US15938417

申请日：2018-03-28

Applicant: Allied Bioscience, Inc.

Inventor： Craig Grossman ,  Gavri Grossman ,  Daniel Moros ,  Misagh Alipour ,  Jie Fang

IPC: A61L29/16 ,  A01N55/00 ,  A61L29/02 ,  A61L29/06 ,  A61L29/08

Abstract: The present disclosure provides antimicrobial coating compositions that are used to form residual antimicrobial coatings on medical implements and medical devices including the components of medical equipment such as CPAP/BiPAP machines. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N, a titanium (IV) species, a 1,2-diol, an α-hydroxy acid, β-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent, and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

公开(公告)号：US11166458B2

公开(公告)日：2021-11-09

申请号：US15968586

申请日：2018-05-01

Applicant: ALLIED BIOSCIENCE, INC.

Inventor： Craig Grossman ,  Gavri Grossman ,  Jie Fang ,  Misagh Alipour

IPC: A01N25/34 ,  B05D7/00 ,  B05D1/04 ,  D06M23/00 ,  D06M11/46 ,  D06M15/423 ,  D06M13/513 ,  A61Q19/10 ,  A61K8/41 ,  A61K8/898 ,  A61K8/58 ,  A61K8/02 ,  A61Q17/00 ,  A01N33/12 ,  A01N55/00

Abstract: A wet wipe is disclosed that provides both contact sanitization of a surface and application of a residual antimicrobial coating on the surface through the same wiping. The wet wipe comprises a substrate such as an absorbent nonwoven fabric and a liquid composition impregnated therein, the liquid composition comprising an organosilane such as the antimicrobial dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride, a non-silane quaternary disinfectant, an organic amine, and a solvent. The non-silane quaternary actives comprise a mixture of actives, and the solvent comprises 60 wt. % isopropanol or more.

公开(公告)号：US20210251810A1

公开(公告)日：2021-08-19

申请号：US17246181

申请日：2021-04-30

Applicant: Allied Bioscience, Inc.

Inventor： Craig Grossman ,  Gavri Grossman ,  Daniel Moros ,  Misagh Alipour ,  Jie Fang

IPC: A61F13/00 ,  A61K31/695 ,  A61F13/84

Abstract: Antimicrobial coating compositions are used to form dried residual antimicrobial coatings on medical dressings including gauze, bandages, gowns, and dry wipers. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N, a titanium (IV) species, a 1,2-diol, an α-hydroxy acid, a β-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

公开(公告)号：US20210308339A1

公开(公告)日：2021-10-07

申请号：US17351453

申请日：2021-06-18

Applicant: Allied Bioscience, Inc.

Inventor： Craig Grossman ,  Gavri Grossman ,  Daniel Moros ,  Misagh Alipour ,  Jie Fang

IPC: A61L29/16 ,  A01N55/00 ,  A61L29/02 ,  A61L29/08 ,  A61L29/06 ,  A61L31/08 ,  A61L31/16

Abstract: The present disclosure provides antimicrobial coating compositions that are used to form residual antimicrobial coatings on medical implements and medical devices including the components of medical equipment such as CPAP/BiPAP machines. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N, a titanium (IV) species, a 1,2-diol, an α-hydroxy acid, a β-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent, and R9, R10 and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

公开(公告)号：US11020278B2

公开(公告)日：2021-06-01

申请号：US15938314

申请日：2018-03-28

Applicant: Allied Bioscience, Inc.

Inventor： Craig Grossman ,  Gavri Grossman ,  Daniel Moros ,  Misagh Alipour ,  Jie Fang

IPC: A61F13/00 ,  A61K31/695 ,  A61F13/84

Abstract: Antimicrobial coating compositions are used to form dried residual antimicrobial coatings on medical dressings including gauze, bandages, gowns and dry wipers. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N a titanium (IV) species, a 1,2-diol, an α-hydroxy acid, a β-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

公开(公告)号：US11826493B2

公开(公告)日：2023-11-28

申请号：US17351453

申请日：2021-06-18

Applicant: Allied Bioscience, Inc.

Inventor： Craig Grossman ,  Gavri Grossman ,  Daniel Moros ,  Misagh Alipour ,  Jie Fang

IPC: A61L29/16 ,  A01N55/00 ,  A61L29/02 ,  A61L29/08 ,  A61L29/06 ,  A61L31/08 ,  A61L31/16

CPC classification number: A61L29/16 ,  A01N55/00 ,  A61L29/02 ,  A61L29/06 ,  A61L29/08 ,  A61L31/08 ,  A61L31/16 ,  A61L2300/202 ,  A61L2300/404 ,  A61L2300/606 ,  A61L2300/802 ,  A61L2420/02 ,  A61L2420/06

Abstract: The present disclosure provides antimicrobial coating compositions that are used to form residual antimicrobial coatings on medical implements and medical devices including the components of medical equipment such as CPAP/BiPAP machines. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N, a titanium (IV) species, a 1,2-diol, an α-hydroxy acid, a β-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent, and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

公开(公告)号：US20180280201A1

公开(公告)日：2018-10-04

申请号：US15938314

申请日：2018-03-28

Applicant: Allied Bioscience, Inc.

Inventor： Craig Grossman ,  Gavri Grossman ,  Daniel Moros ,  Misagh Alipour ,  Jie Fang

IPC: A61F13/00 ,  A61F13/84 ,  A61K31/695

Abstract: Antimicrobial coating compositions are used to form dried residual antimicrobial coatings on medical dressings including gauze, bandages, gowns and dry wipers. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N a titanium (IV) species, a 1,2-diol, an α-hydroxy acid, a β-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

公开(公告)号：US20180243790A1

公开(公告)日：2018-08-30

申请号：US15968586

申请日：2018-05-01

Applicant: ALLIED BIOSCIENCE, INC.

Inventor： Craig Grossman ,  Gavri Grossman ,  Jie Fang ,  Misagh Alipour

IPC: B05D7/00 ,  B05D1/04 ,  D06M23/00 ,  D06M11/46 ,  D06M13/513 ,  D06M15/423

CPC classification number: B05D7/52 ,  A01N25/34 ,  A01N33/12 ,  A01N55/00 ,  A61K8/0208 ,  A61K8/41 ,  A61K8/585 ,  A61K8/898 ,  A61Q17/005 ,  A61Q19/10 ,  B05D1/04 ,  B05D2601/24 ,  D06M11/46 ,  D06M13/513 ,  D06M15/423 ,  D06M23/005 ,  A01N31/02

Abstract: A wet wipe is disclosed that provides both contact sanitization of a surface and application of a residual antimicrobial coating on the surface through the same wiping. The wet wipe comprises a substrate such as an absorbent nonwoven fabric and a liquid composition impregnated therein, the liquid composition comprising an organosilane such as the antimicrobial dimethyloctadecyl[3-(trimethoxysilyl)propyl] ammonium chloride, a non-silane quaternary disinfectant, an organic amine, and a solvent. The non-silane quaternary actives comprise a mixture of actives, and the solvent comprises 60 wt. % isopropanol or more.