公开(公告)号：US11826493B2

公开(公告)日：2023-11-28

申请号：US17351453

申请日：2021-06-18

Applicant: Allied Bioscience, Inc.

Inventor： Craig Grossman ,  Gavri Grossman ,  Daniel Moros ,  Misagh Alipour ,  Jie Fang

IPC: A61L29/16 ,  A01N55/00 ,  A61L29/02 ,  A61L29/08 ,  A61L29/06 ,  A61L31/08 ,  A61L31/16

CPC classification number: A61L29/16 ,  A01N55/00 ,  A61L29/02 ,  A61L29/06 ,  A61L29/08 ,  A61L31/08 ,  A61L31/16 ,  A61L2300/202 ,  A61L2300/404 ,  A61L2300/606 ,  A61L2300/802 ,  A61L2420/02 ,  A61L2420/06

Abstract: The present disclosure provides antimicrobial coating compositions that are used to form residual antimicrobial coatings on medical implements and medical devices including the components of medical equipment such as CPAP/BiPAP machines. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N, a titanium (IV) species, a 1,2-diol, an α-hydroxy acid, a β-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent, and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

公开(公告)号：US11369114B2

公开(公告)日：2022-06-28

申请号：US17177850

申请日：2021-02-17

Applicant: ALLIED BIOSCIENCE, INC.

Inventor： Gavri Grossman ,  Jie Fang ,  Parham Asgari ,  Maha El-Sayed ,  Craig Grossman ,  Daniel Moros

IPC: C09D183/08 ,  A01N55/00 ,  B05D1/04 ,  C23C26/00 ,  C09D179/02 ,  B05D7/00 ,  B05D7/14 ,  B05D1/02 ,  A01N33/08 ,  A01N25/02 ,  C09D5/14 ,  A61L2/00 ,  A01N59/16 ,  C08G77/26 ,  C09D183/00 ,  C08K3/22 ,  C09D183/06 ,  C07F7/08

Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.

公开(公告)号：US20210169081A1

公开(公告)日：2021-06-10

申请号：US17177850

申请日：2021-02-17

Applicant: ALLIED BIOSCIENCE, INC.

Inventor： Gavri Grossman ,  Jie Fang ,  Parham Asgari ,  Maha El-Sayed ,  Craig Grossman ,  Daniel Moros

IPC: A01N55/00 ,  C09D183/08 ,  A01N59/16 ,  C09D5/14 ,  A01N33/08 ,  B05D7/14 ,  A61L2/00 ,  C09D179/02 ,  C23C26/00 ,  C08G77/26 ,  B05D1/04 ,  A01N25/02 ,  B05D1/02 ,  B05D7/00 ,  C09D183/00 ,  C07F7/08 ,  C09D183/06 ,  C08K3/22

Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.

公开(公告)号：US10238114B2

公开(公告)日：2019-03-26

申请号：US15432428

申请日：2017-02-14

Applicant: Allied Bioscience, Inc.

Inventor： Daniel Moros ,  Craig Grossman

IPC: C09D183/08 ,  A01N55/00 ,  A01N59/16 ,  A61L2/00 ,  C09D5/14 ,  A01N25/02 ,  A01N33/08 ,  B05D1/02 ,  B05D7/14 ,  B05D7/00 ,  C09D179/02 ,  C23C26/00 ,  B05D1/04 ,  C08G77/26 ,  C09D183/00 ,  C08K3/22

Abstract: An anti-microbial coating formulation consisting essentially of triethanolamine and a silane.

公开(公告)号：US20180280201A1

公开(公告)日：2018-10-04

申请号：US15938314

申请日：2018-03-28

Applicant: Allied Bioscience, Inc.

Inventor： Craig Grossman ,  Gavri Grossman ,  Daniel Moros ,  Misagh Alipour ,  Jie Fang

IPC: A61F13/00 ,  A61F13/84 ,  A61K31/695

Abstract: Antimicrobial coating compositions are used to form dried residual antimicrobial coatings on medical dressings including gauze, bandages, gowns and dry wipers. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N a titanium (IV) species, a 1,2-diol, an α-hydroxy acid, a β-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

公开(公告)号：US20210251810A1

公开(公告)日：2021-08-19

申请号：US17246181

申请日：2021-04-30

Applicant: Allied Bioscience, Inc.

Inventor： Craig Grossman ,  Gavri Grossman ,  Daniel Moros ,  Misagh Alipour ,  Jie Fang

IPC: A61F13/00 ,  A61K31/695 ,  A61F13/84

Abstract: Antimicrobial coating compositions are used to form dried residual antimicrobial coatings on medical dressings including gauze, bandages, gowns, and dry wipers. Antimicrobial coating compositions comprise at least one of an organosilane (R1O)3Si—R2—Z, an organic amine R9R10R11N, a titanium (IV) species, a 1,2-diol, an α-hydroxy acid, a β-hydroxy acid, and an organosilane grafted parylene polymer, wherein R1 is H, alkyl, substituted alkyl, aryl or substituted aryl, R2 is a bivalent linker, Z is a nucleophile, leaving group, or quaternary nitrogen substituent and R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

公开(公告)号：US10993441B2

公开(公告)日：2021-05-04

申请号：US16591785

申请日：2019-10-03

Applicant: ALLIED BIOSCIENCE, INC.

Inventor： Gavri Grossman ,  Jie Fang ,  Parham Asgari ,  Maha El-Sayed ,  Craig Grossman ,  Daniel Moros

IPC: C08G77/26 ,  A01N55/00 ,  B05D1/04 ,  C23C26/00 ,  C09D179/02 ,  B05D7/00 ,  B05D7/14 ,  B05D1/02 ,  A01N33/08 ,  A01N25/02 ,  C09D5/14 ,  A61L2/00 ,  A01N59/16 ,  C09D183/08 ,  C09D183/00 ,  C08K3/22 ,  C09D183/06 ,  C07F7/08

Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.

公开(公告)号：US20180368648A1

公开(公告)日：2018-12-27

申请号：US16013750

申请日：2018-06-20

Applicant: Allied Bioscience, Inc.

Inventor： Craig Grossman ,  Gavri Grossman ,  Daniel Moros

IPC: A47L13/16 ,  A01N55/00 ,  A01N33/08 ,  A01N25/34

Abstract: The disclosure provides an antimicrobial sponge comprising: a porous sponge substrate; and an antimicrobial coating composition dried therein, the composition comprising: at least one organosilane of formula (R1O)3Si—R2—Z; and an organic amine of formula R9R10R11N, wherein each R1 is independently H, alkyl, substituted alkyl, aryl, or substituted aryl, R2 is a bivalent linker, and Z is a nucleophile, a leaving group or a quaternary nitrogen substituent, and wherein R9, R10, and R11 are independently H, alkyl, substituted alkyl, aryl, substituted aryl or cyclic.

公开(公告)号：US09963596B2

公开(公告)日：2018-05-08

申请号：US15432567

申请日：2017-02-14

Applicant: Allied Bioscience, Inc.

Inventor： Daniel Moros ,  Craig Grossman ,  Gavri Grossman

IPC: C09D183/08 ,  C09D5/14 ,  C08G77/26 ,  B05D1/02

CPC classification number: C09D5/14 ,  B05D1/02 ,  C08G73/0246 ,  C08G77/26 ,  C08G77/62 ,  C08K3/22 ,  C08K2003/2241 ,  C09D183/08 ,  C09D183/16 ,  C08L83/14

Abstract: The invention relates to an antimicrobial coating composition formed by admixing choline bitartrate or choline chloride, an aminopropyltrialkoxysilane and water. This coating composition is preferably sprayed onto a surface and allowed to dry. Preferably the surface is a stainless steel surface. The coating reduces the amount of E. Coli on the surface of the substrate.

公开(公告)号：US20170166754A1

公开(公告)日：2017-06-15

申请号：US15432443

申请日：2017-02-14

Applicant: Allied Bioscience, Inc.

Inventor： Daniel Moros ,  Craig Grossman

IPC: C09D5/14 ,  C23C26/00 ,  B05D1/02 ,  B05D7/14 ,  A01N55/00 ,  A01N25/02

CPC classification number: A01N55/00 ,  A01N25/02 ,  A01N33/08 ,  A01N59/16 ,  A61L2/00 ,  B05D1/02 ,  B05D1/04 ,  B05D7/14 ,  B05D7/544 ,  C08G77/26 ,  C08K3/22 ,  C08K2003/2241 ,  C09D5/14 ,  C09D179/02 ,  C09D183/00 ,  C09D183/08 ,  C23C26/00 ,  A01N2300/00

Abstract: An anti-microbial coating formulation consisting essentially of triethanolamine and a silane.