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公开(公告)号:US20160258857A1
公开(公告)日:2016-09-08
申请号:US15044636
申请日:2016-02-16
Applicant: Abbott Laboratories
Inventor: Martin Krockenberger , Jiong Wu , Bodo Roemer , Giacomo Vacca
CPC classification number: G01N15/1404 , G01N15/00 , G01N15/1429 , G01N15/1459 , G01N21/53 , G01N33/49 , G01N33/4915 , G01N33/492 , G01N2015/0073 , G01N2015/0076 , G01N2015/008 , G01N2015/0084 , G01N2015/1006 , G01N2015/1486 , G01N2800/22 , Y10T436/101666
Abstract: A method for identifying, analyzing, and quantifying the cellular components of whole blood by means of an automated hematology analyzer and the detection of the light scattered, absorbed, and fluorescently emitted by each cell. More particularly, the aforementioned method involves identifying, analyzing, and quantifying the cellular components of whole blood by means of a light source having a wavelength ranging from about 400 nm to about 450 nm and multiple in-flow optical measurements and staining without the need for lysing red blood cells.
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公开(公告)号:US09261495B2
公开(公告)日:2016-02-16
申请号:US14562046
申请日:2014-12-05
Applicant: Abbott Laboratories
Inventor: Martin Krockenberger , Richard Bordenkircher , Diana Garrett , John Glazier , James Bearden , Bodo Roemer , Giacomo Vacca
CPC classification number: G01N33/4915 , G01N15/1429 , G01N15/1459 , G01N33/492 , G01N2015/0069 , G01N2015/008 , G01N2015/1006 , G01N2015/1486 , G01N2015/1488 , Y10T436/101666 , Y10T436/2575
Abstract: A hematology analyzer is provided. In certain embodiments, the hematology analyzer comprises: a) a flow cell; b) a light source for directing light to the flow cell; c) a plurality of detectors for detecting a plurality of optical characteristics of a blood cell passing through the flow cell; and d) a data analysis workstation programmed to: i. enumerate test blood cells passing through the flow cell; and ii. flag a blood sample as containing lysis-resistant red blood cells or fragile white blood cells.
Abstract translation: 提供血液分析仪。 在某些实施方案中,血液分析仪包括:a)流动池; b)用于将光引导到流动池的光源; c)多个检测器,用于检测通过流通池的血细胞的多个光学特性; 和d)数据分析工作站被编程为:i。 列举通过流动池的测试血液细胞; 和ii。 标记含有裂解抗性红细胞或脆弱白细胞的血液样品。
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公开(公告)号:US11193875B2
公开(公告)日:2021-12-07
申请号:US15581395
申请日:2017-04-28
Applicant: Abbott Laboratories
Inventor: Martin Krockenberger , Jiong Wu , Bodo Roemer , Giacomo Vacca
Abstract: A method for identifying, analyzing, and quantifying the cellular components of whole blood by means of an automated hematology analyzer and the detection of the light scattered, absorbed, and fluorescently emitted by each cell. More particularly, the aforementioned method involves identifying, analyzing, and quantifying the cellular components of whole blood by means of a light source having a wavelength ranging from about 400 nm to about 450 nm and multiple in-flow optical measurements and staining without the need for lysing red blood cells.
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公开(公告)号:US09618498B2
公开(公告)日:2017-04-11
申请号:US15044631
申请日:2016-02-16
Applicant: Abbott Laboratories
Inventor: Martin Krockenberger , Richard Bordenkircher , Diana Garrett , John Glazier , James Bearden , Bodo Roemer , Giacomo Vacca
CPC classification number: G01N33/4915 , G01N15/1429 , G01N15/1459 , G01N33/492 , G01N2015/0069 , G01N2015/008 , G01N2015/1006 , G01N2015/1486 , G01N2015/1488 , Y10T436/101666 , Y10T436/2575
Abstract: A hematology analyzer is provided. In certain embodiments, the hematology analyzer comprises: a) a flow cell; b) a light source for directing light to the flow cell; c) a plurality of detectors for detecting a plurality of optical characteristics of a blood cell passing through the flow cell; and d) a data analysis workstation programmed to: i. enumerate test blood cells passing through the flow cell; and ii. flag a blood sample as containing lysis-resistant red blood cells or fragile white blood cells.
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公开(公告)号:US11085914B2
公开(公告)日:2021-08-10
申请号:US15477994
申请日:2017-04-03
Applicant: Abbott Laboratories
Inventor: Martin Krockenberger , Richard Bordenkircher , Diana Garrett , John Glazier , James Bearden , Bodo Roemer , Giacomo Vacca
Abstract: A hematology analyzer is provided. In certain embodiments, the hematology analyzer comprises: a) a flow cell; b) a light source for directing light to the flow cell; c) a plurality of detectors for detecting a plurality of optical characteristics of a blood cell passing through the flow cell; and d) a data analysis workstation programmed to: i. enumerate test blood cells passing through the flow cell; and ii. flag a blood sample as containing lysis-resistant red blood cells or fragile white blood cells.
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公开(公告)号:US20170276591A1
公开(公告)日:2017-09-28
申请号:US15581395
申请日:2017-04-28
Applicant: Abbott Laboratories
Inventor: Martin Krockenberger , Jiong Wu , Bodo Roemer , Giacomo Vacca
CPC classification number: G01N15/1404 , G01N15/00 , G01N15/1429 , G01N15/1459 , G01N21/53 , G01N33/49 , G01N33/4915 , G01N33/492 , G01N2015/0073 , G01N2015/0076 , G01N2015/008 , G01N2015/0084 , G01N2015/1006 , G01N2015/1486 , G01N2800/22 , Y10T436/101666
Abstract: A method for identifying, analyzing, and quantifying the cellular components of whole blood by means of an automated hematology analyzer and the detection of the light scattered, absorbed, and fluorescently emitted by each cell. More particularly, the aforementioned method involves identifying, analyzing, and quantifying the cellular components of whole blood by means of a light source having a wavelength ranging from about 400 nm to about 450 nm and multiple in-flow optical measurements and staining without the need for lysing red blood cells.
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公开(公告)号:US20160266092A1
公开(公告)日:2016-09-15
申请号:US15044631
申请日:2016-02-16
Applicant: Abbott Laboratories
Inventor: Martin Krockenberger , Richard Bordenkircher , Diana Garrett , John Glazier , James Bearden , Bodo Roemer , Giacomo Vacca
CPC classification number: G01N33/4915 , G01N15/1429 , G01N15/1459 , G01N33/492 , G01N2015/0069 , G01N2015/008 , G01N2015/1006 , G01N2015/1486 , G01N2015/1488 , Y10T436/101666 , Y10T436/2575
Abstract: A hematology analyzer is provided. In certain embodiments, the hematology analyzer comprises: a) a flow cell; b) a light source for directing light to the flow cell; c) a plurality of detectors for detecting a plurality of optical characteristics of a blood cell passing through the flow cell; and d) a data analysis workstation programmed to: i. enumerate test blood cells passing through the flow cell; and ii. flag a blood sample as containing lysis-resistant red blood cells or fragile white blood cells.
Abstract translation: 提供血液分析仪。 在某些实施方案中,血液分析仪包括:a)流动池; b)用于将光引导到流动池的光源; c)多个检测器,用于检测通过流通池的血细胞的多个光学特性; 和d)数据分析工作站被编程为:i。 列举通过流动池的测试血液细胞; 和ii。 标记含有裂解抗性红细胞或脆弱白细胞的血液样品。
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公开(公告)号:US20150160188A1
公开(公告)日:2015-06-11
申请号:US14562046
申请日:2014-12-05
Applicant: Abbott Laboratories
Inventor: Martin Krockenberger , Richard Bordenkircher , Diana Garrett , John Glazier , James Bearden , Bodo Roemer , Giacomo Vacca
IPC: G01N33/49
CPC classification number: G01N33/4915 , G01N15/1429 , G01N15/1459 , G01N33/492 , G01N2015/0069 , G01N2015/008 , G01N2015/1006 , G01N2015/1486 , G01N2015/1488 , Y10T436/101666 , Y10T436/2575
Abstract: A hematology analyzer is provided. In certain embodiments, the hematology analyzer comprises: a) a flow cell; b) a light source for directing light to the flow cell; c) a plurality of detectors for detecting a plurality of optical characteristics of a blood cell passing through the flow cell; and d) a data analysis workstation programmed to: i. enumerate test blood cells passing through the flow cell; and ii. flag a blood sample as containing lysis-resistant red blood cells or fragile white blood cells.
Abstract translation: 提供血液分析仪。 在某些实施方案中,血液分析仪包括:a)流动池; b)用于将光引导到流动池的光源; c)多个检测器,用于检测通过流通池的血细胞的多个光学特性; 和d)数据分析工作站被编程为:i。 列举通过流动池的测试血液细胞; 和ii。 标记含有裂解抗性红细胞或脆弱白细胞的血液样品。
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公开(公告)号:US20170269059A1
公开(公告)日:2017-09-21
申请号:US15477994
申请日:2017-04-03
Applicant: Abbott Laboratories
Inventor: Martin Krockenberger , Richard Bordenkircher , Diana Garrett , John Glazier , James Bearden , Bodo Roemer , Giacomo Vacca
CPC classification number: G01N33/4915 , G01N15/1429 , G01N15/1459 , G01N33/492 , G01N2015/0069 , G01N2015/008 , G01N2015/1006 , G01N2015/1486 , G01N2015/1488 , Y10T436/101666 , Y10T436/2575
Abstract: A hematology analyzer is provided. In certain embodiments, the hematology analyzer comprises: a) a flow cell; b) a light source for directing light to the flow cell; c) a plurality of detectors for detecting a plurality of optical characteristics of a blood cell passing through the flow cell; and d) a data analysis workstation programmed to: i. enumerate test blood cells passing through the flow cell; and ii. flag a blood sample as containing lysis-resistant red blood cells or fragile white blood cells.
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公开(公告)号:US09638621B2
公开(公告)日:2017-05-02
申请号:US15044636
申请日:2016-02-16
Applicant: Abbott Laboratories
Inventor: Martin Krockenberger , Jiong Wu , Bodo Roemer , Giacomo Vacca
CPC classification number: G01N15/1404 , G01N15/00 , G01N15/1429 , G01N15/1459 , G01N21/53 , G01N33/49 , G01N33/4915 , G01N33/492 , G01N2015/0073 , G01N2015/0076 , G01N2015/008 , G01N2015/0084 , G01N2015/1006 , G01N2015/1486 , G01N2800/22 , Y10T436/101666
Abstract: A method for identifying, analyzing, and quantifying the cellular components of whole blood by means of an automated hematology analyzer and the detection of the light scattered, absorbed, and fluorescently emitted by each cell. More particularly, the aforementioned method involves identifying, analyzing, and quantifying the cellular components of whole blood by means of a light source having a wavelength ranging from about 400 nm to about 450 nm and multiple in-flow optical measurements and staining without the need for lysing red blood cells.
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