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公开(公告)号：US20160258857A1
公开(公告)日：2016-09-08
申请号：US15044636
申请日：2016-02-16
Applicant: Abbott Laboratories
Inventor： Martin Krockenberger , Jiong Wu , Bodo Roemer , Giacomo Vacca
CPC classification number: G01N15/1404 , G01N15/00 , G01N15/1429 , G01N15/1459 , G01N21/53 , G01N33/49 , G01N33/4915 , G01N33/492 , G01N2015/0073 , G01N2015/0076 , G01N2015/008 , G01N2015/0084 , G01N2015/1006 , G01N2015/1486 , G01N2800/22 , Y10T436/101666
Abstract: A method for identifying, analyzing, and quantifying the cellular components of whole blood by means of an automated hematology analyzer and the detection of the light scattered, absorbed, and fluorescently emitted by each cell. More particularly, the aforementioned method involves identifying, analyzing, and quantifying the cellular components of whole blood by means of a light source having a wavelength ranging from about 400 nm to about 450 nm and multiple in-flow optical measurements and staining without the need for lysing red blood cells.
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公开(公告)号：US09261495B2
公开(公告)日：2016-02-16
申请号：US14562046
申请日：2014-12-05
Applicant: Abbott Laboratories
Inventor： Martin Krockenberger , Richard Bordenkircher , Diana Garrett , John Glazier , James Bearden , Bodo Roemer , Giacomo Vacca
CPC classification number: G01N33/4915 , G01N15/1429 , G01N15/1459 , G01N33/492 , G01N2015/0069 , G01N2015/008 , G01N2015/1006 , G01N2015/1486 , G01N2015/1488 , Y10T436/101666 , Y10T436/2575
Abstract: A hematology analyzer is provided. In certain embodiments, the hematology analyzer comprises: a) a flow cell; b) a light source for directing light to the flow cell; c) a plurality of detectors for detecting a plurality of optical characteristics of a blood cell passing through the flow cell; and d) a data analysis workstation programmed to: i. enumerate test blood cells passing through the flow cell; and ii. flag a blood sample as containing lysis-resistant red blood cells or fragile white blood cells.
Abstract translation: 提供血液分析仪。 在某些实施方案中，血液分析仪包括：a）流动池; b）用于将光引导到流动池的光源; c）多个检测器，用于检测通过流通池的血细胞的多个光学特性; 和d）数据分析工作站被编程为：i。 列举通过流动池的测试血液细胞; 和ii。 标记含有裂解抗性红细胞或脆弱白细胞的血液样品。
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公开(公告)号：US20180340881A1
公开(公告)日：2018-11-29
申请号：US15987620
申请日：2018-05-23
Applicant: Abbott Laboratories
Inventor： Martin Krockenberger
IPC: G01N15/14
Abstract: The present disclosure includes provides methods for analyzing biological samples to identify, classify, and/or quantify platelets in the sample. The present disclosure also provides systems and methods for analyzing a blood sample to determine presence of platelet clumps in the sample. Also provided are systems configured for performing the disclosed methods and computer readable medium storing instructions for performing steps of the disclosed methods.
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公开(公告)号：US11193875B2
公开(公告)日：2021-12-07
申请号：US15581395
申请日：2017-04-28
Applicant: Abbott Laboratories
Inventor： Martin Krockenberger , Jiong Wu , Bodo Roemer , Giacomo Vacca
Abstract: A method for identifying, analyzing, and quantifying the cellular components of whole blood by means of an automated hematology analyzer and the detection of the light scattered, absorbed, and fluorescently emitted by each cell. More particularly, the aforementioned method involves identifying, analyzing, and quantifying the cellular components of whole blood by means of a light source having a wavelength ranging from about 400 nm to about 450 nm and multiple in-flow optical measurements and staining without the need for lysing red blood cells.
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公开(公告)号：US20210131938A1
公开(公告)日：2021-05-06
申请号：US17094643
申请日：2020-11-10
Applicant: Abbott Laboratories
Inventor： Giacomo Vacca , Martin Krockenberger , Diana Garrett
Abstract: Provided herein is a method for determining the volume or hemoglobin content of an individual red blood cell in a sample containing a population of red blood cells. The method may be performed on a hematology analyzer. Also provided are a hematology analyzer for performing the method and a computer-readable medium containing programming for performing the method.
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Patent Agency Ranking
公开(公告)号：US20210123852A1
公开(公告)日：2021-04-29
申请号：US16994254
申请日：2020-08-14
Applicant: Abbott Laboratories
Inventor： Martin Krockenberger
IPC: G01N15/14
Abstract: The present disclosure includes provides methods for analyzing biological samples to identify, classify, and/or quantify platelets in the sample. The present disclosure also provides systems and methods for analyzing a blood sample to determine presence of platelet clumps in the sample. Also provided are systems configured for performing the disclosed methods and computer readable medium storing instructions for performing steps of the disclosed methods.
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公开(公告)号：US09933349B2
公开(公告)日：2018-04-03
申请号：US15044635
申请日：2016-02-16
Applicant: Abbott Laboratories
Inventor： Giacomo Vacca , Martin Krockenberger , Diana Garrett
CPC classification number: G01N15/06 , G01N15/0656 , G01N15/1459 , G01N15/147 , G01N33/4915 , G01N33/492 , G01N33/721 , G01N2015/0065 , G01N2015/0073 , G01N2015/0687 , G01N2015/0693 , G01N2333/805 , Y10T436/101666
Abstract: Provided herein is a method for determining the volume or hemoglobin content of an individual red blood cell in a sample containing a population of red blood cells. The method may be performed on a hematology analyzer. Also provided are a hematology analyzer for performing the method and a computer-readable medium containing programming for performing the method.
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公开(公告)号：US09618498B2
公开(公告)日：2017-04-11
申请号：US15044631
申请日：2016-02-16
Applicant: Abbott Laboratories
Inventor： Martin Krockenberger , Richard Bordenkircher , Diana Garrett , John Glazier , James Bearden , Bodo Roemer , Giacomo Vacca
CPC classification number: G01N33/4915 , G01N15/1429 , G01N15/1459 , G01N33/492 , G01N2015/0069 , G01N2015/008 , G01N2015/1006 , G01N2015/1486 , G01N2015/1488 , Y10T436/101666 , Y10T436/2575
Abstract: A hematology analyzer is provided. In certain embodiments, the hematology analyzer comprises: a) a flow cell; b) a light source for directing light to the flow cell; c) a plurality of detectors for detecting a plurality of optical characteristics of a blood cell passing through the flow cell; and d) a data analysis workstation programmed to: i. enumerate test blood cells passing through the flow cell; and ii. flag a blood sample as containing lysis-resistant red blood cells or fragile white blood cells.
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9.发明申请Method for Determining Volume and Hemoglobin Content of Individual Red Blood Cells 有权测定个体红细胞体积和血红蛋白含量的方法公开(公告)号：US20150160243A1
公开(公告)日：2015-06-11
申请号：US14562058
申请日：2014-12-05
Applicant: Abbott Laboratories
Inventor： Giacomo Vacca , Martin Krockenberger , Diana Garrett
CPC classification number: G01N15/06 , G01N15/0656 , G01N15/1459 , G01N15/147 , G01N33/4915 , G01N33/492 , G01N33/721 , G01N2015/0065 , G01N2015/0073 , G01N2015/0687 , G01N2015/0693 , G01N2333/805 , Y10T436/101666
Abstract: Provided herein is a method for determining the volume or hemoglobin content of an individual red blood cell in a sample containing a population of red blood cells. The method may be performed on a hematology analyzer. Also provided are a hematology analyzer for performing the method and a computer-readable medium containing programming for performing the method.
Abstract translation: 本文提供了用于测定含有红细胞群体的样品中各个红细胞的体积或血红蛋白含量的方法。 该方法可以在血液分析仪上进行。 还提供了用于执行该方法的血液分析仪和包含用于执行该方法的程序的计算机可读介质。
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公开(公告)号：US11085914B2
公开(公告)日：2021-08-10
申请号：US15477994
申请日：2017-04-03
Applicant: Abbott Laboratories
Inventor： Martin Krockenberger , Richard Bordenkircher , Diana Garrett , John Glazier , James Bearden , Bodo Roemer , Giacomo Vacca
Abstract: A hematology analyzer is provided. In certain embodiments, the hematology analyzer comprises: a) a flow cell; b) a light source for directing light to the flow cell; c) a plurality of detectors for detecting a plurality of optical characteristics of a blood cell passing through the flow cell; and d) a data analysis workstation programmed to: i. enumerate test blood cells passing through the flow cell; and ii. flag a blood sample as containing lysis-resistant red blood cells or fragile white blood cells.
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