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公开(公告)号：US20220098150A1
公开(公告)日：2022-03-31
申请号：US17322382
申请日：2021-05-17
Applicant: Biogen MA Inc.
Inventor： Nishanth Gopinathan , Erwin Irdam , William Kiesman , Daw-long A. Kwok , Yiqing Lin , Frederick Osei-Yeboah , Matthew Peterson , Kenny Tran , Kalyan Vasudevan
IPC: C07D207/16
Abstract: The present invention is directed to novel crystalline forms of 5-(4-{[2-fluorophenyl)methyl]oxy}phenyl-prolinamide hydrochloride, to the use of said crystalline forms in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said crystalline forms and processes for their preparation.
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公开(公告)号：US20180297992A1
公开(公告)日：2018-10-18
申请号：US15952505
申请日：2018-04-13
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D405/14 , C07D413/14 , A61P43/00
CPC classification number: C07D417/14 , A61K31/44 , A61K31/443 , A61K31/506 , A61P43/00 , C07B2200/13 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号：US11858926B2
公开(公告)日：2024-01-02
申请号：US17871157
申请日：2022-07-22
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D413/14 , C07D405/14 , C07D471/04 , A61P43/00 , A61P1/16
CPC classification number: C07D417/14 , A61P1/16 , A61P43/00 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07B2200/13
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号：US10961237B2
公开(公告)日：2021-03-30
申请号：US16534540
申请日：2019-08-07
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D413/14 , C07D405/14 , C07D471/04 , A61P43/00 , A61P1/16
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号：US11427577B2
公开(公告)日：2022-08-30
申请号：US17183702
申请日：2021-02-24
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D413/14 , C07D405/14 , C07D471/04 , A61P43/00 , A61P1/16
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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Patent Agency Ranking
公开(公告)号：US20200239459A1
公开(公告)日：2020-07-30
申请号：US16534540
申请日：2019-08-07
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D413/14 , A61P43/00 , C07D405/14 , C07D471/04 , A61P1/16
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号：US10189829B2
公开(公告)日：2019-01-29
申请号：US16113455
申请日：2018-08-27
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D405/14 , C07D413/14 , A61P43/00
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号：US20210340135A1
公开(公告)日：2021-11-04
申请号：US17183702
申请日：2021-02-24
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D413/14 , A61P43/00 , C07D405/14 , C07D471/04 , A61P1/16
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号：US20200062705A1
公开(公告)日：2020-02-27
申请号：US16610817
申请日：2018-05-18
Applicant: Biogen MA Inc.
Inventor： Nishanth Gopinathan , Erwin Irdam , William Kiesman , Daw-long A. Kwok , Yiqing Lin , Frederick Osei-Yeboah , Matthew Peterson , Kenny Tran , Kalyan Vasudevan
IPC: C07D207/16
Abstract: The present invention is directed to novel crystalline forms of 5-(4-{[(2-fluorophenyl)methyl]oxy}phenyl)-prolinamide hydrochloride, to the use of said crystalline forms in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said crystalline forms and processes for their preparation.
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公开(公告)号：US20180362522A1
公开(公告)日：2018-12-20
申请号：US16113455
申请日：2018-08-27
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , A61P43/00 , C07D403/14 , C07D405/14 , C07D413/14
CPC classification number: C07D417/14 , A61K31/44 , A61K31/443 , A61K31/506 , A61P43/00 , C07B2200/13 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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