公开(公告)号：US20220098150A1

公开(公告)日：2022-03-31

申请号：US17322382

申请日：2021-05-17

Applicant: Biogen MA Inc.

Inventor： Nishanth Gopinathan ,  Erwin Irdam ,  William Kiesman ,  Daw-long A. Kwok ,  Yiqing Lin ,  Frederick Osei-Yeboah ,  Matthew Peterson ,  Kenny Tran ,  Kalyan Vasudevan

IPC: C07D207/16

Abstract: The present invention is directed to novel crystalline forms of 5-(4-{[2-fluorophenyl)methyl]oxy}phenyl-prolinamide hydrochloride, to the use of said crystalline forms in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said crystalline forms and processes for their preparation.

公开(公告)号：US20200062705A1

公开(公告)日：2020-02-27

申请号：US16610817

申请日：2018-05-18

Applicant: Biogen MA Inc.

Inventor： Nishanth Gopinathan ,  Erwin Irdam ,  William Kiesman ,  Daw-long A. Kwok ,  Yiqing Lin ,  Frederick Osei-Yeboah ,  Matthew Peterson ,  Kenny Tran ,  Kalyan Vasudevan

IPC: C07D207/16

Abstract: The present invention is directed to novel crystalline forms of 5-(4-{[(2-fluorophenyl)methyl]oxy}phenyl)-prolinamide hydrochloride, to the use of said crystalline forms in treating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said crystalline forms and processes for their preparation.