公开(公告)号：US20240141326A1

公开(公告)日：2024-05-02

申请号：US18278586

申请日：2022-02-24

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Daniel DAR ,  Dianne K. NEWMAN ,  Kirsten FRIEDA ,  Long CAI

IPC: C12N15/10

CPC classification number: C12N15/1065 ,  C12N15/1055 ,  C12N15/1058

Abstract: Method for detecting and barcoding the molecular changes occurring in two or more samples upon exposure to different stimuli. This disclosure herein sets for methods that allow a targeted transcriptome-imaging approach that records both gene-expression and spatial context within microscale assemblies at a single-cell and molecule resolution on biological samples. This disclosure herein sets for methods that allows the application to a variety of biological samples for the study of cellular processes, growth, and interactions between biological samples.