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Patent Agency Ranking
公开(公告)号：US09655774B2
公开(公告)日：2017-05-23
申请号：US14744439
申请日：2015-06-19
Inventor： Yu-Chong Tai , Nicholas Scianmarello , Dongyang Kang , Jungwook Park , Mark S. Humayun , Karthik Murali , Amir H. Kashani , Hossein Nazari Khanamiri
CPC classification number: A61F9/0017 , A61F2240/001 , A61F2250/0068 , B29C39/10 , B29C41/36 , B29C65/02 , B29C66/1142 , B29C66/3242 , B29C66/54 , B29C66/71 , B29C66/73754 , B29C66/919 , B29C66/949 , B29K2083/005 , B29L2031/7548
Abstract: A medical device having a permeable bag connected by a non-permeable cannula to a discharge sac is described along with a manufacturing process and surgical implantation method. The permeable portions of the device have pores that are sized to be permeable to a predetermined class of small molecules, such as oxygen, nitrous oxide, or other therapeutic agents. Once absorbed inside the device, the small molecules are then passively transported, by a concentration gradient of the small molecules, to the discharge sac to be disbursed. A metal tube or other strip can be included in the cannula to assist a surgeon in orienting the device within the body.
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公开(公告)号：US20150273197A1
公开(公告)日：2015-10-01
申请号：US14433583
申请日：2013-10-07
Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA , DOHENY EYE INSTITUTE , CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Mark S. Humayun , Karthik Murali , Ramiro Magalhaes Ribeiro , Yu-chong Tai , Nicholas Scianmarello
CPC classification number: A61M37/00 , A61F9/0017 , A61M5/14276 , A61M2005/14204 , A61M2205/3334 , A61M2210/0612 , C25B1/02 , C25B9/08
Abstract: An implantable oxygenator may have a configuration that is suitable for implantation within a human body be implanted within a human body, such as within a human eye. The implantable oxygenator may include an electrolyte reservoir having a configuration suitable for storing electrolyte and an electrolysis system having a configuration that performs electrolysis on a portion of the electrolyte, thereby producing oxygen in the region of the electrolysis system.
Abstract translation: 植入式氧合器可以具有适合于植入在人体内的人体内的构造，例如在人眼内。 可植入氧合器可以包括具有适于储存电解质的结构的电解质储存器和具有对电解质的一部分进行电解的结构的电解系统，从而在电解系统的区域中产生氧。
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公开(公告)号：US20150366707A1
公开(公告)日：2015-12-24
申请号：US14744439
申请日：2015-06-19
Inventor： Yu-Chong Tai , Nicholas Scianmarello , Dongyang Kang , Jungwook Park , Mark S. Humayun , Karthik Murali , Amir H. Kashani , Hossein Nazari Khanamiri
CPC classification number: A61F9/0017 , A61F2240/001 , A61F2250/0068 , B29C39/10 , B29C41/36 , B29C65/02 , B29C66/1142 , B29C66/3242 , B29C66/54 , B29C66/71 , B29C66/73754 , B29C66/919 , B29C66/949 , B29K2083/005 , B29L2031/7548
Abstract: A medical device having a permeable bag connected by a non-permeable cannula to a discharge sac is described along with a manufacturing process and surgical implantation method. The permeable portions of the device have pores that are sized to be permeable to a predetermined class of small molecules, such as oxygen, nitrous oxide, or other therapeutic agents. Once absorbed inside the device, the small molecules are then passively transported, by a concentration gradient of the small molecules, to the discharge sac to be disbursed. A metal tube or other strip can be included in the cannula to assist a surgeon in orienting the device within the body.
Abstract translation: 具有通过非渗透性套管连接到排出囊的可渗透袋的医疗装置与制造过程和手术植入方法一起被描述。 装置的可渗透部分具有尺寸适于对预定类型的小分子例如氧气，一氧化二氮或其它治疗剂可渗透的孔。 一旦被吸收在设备内部，小分子就被小分子的浓度梯度被动地运送到排出囊。 套管中可以包括金属管或其它条，以帮助外科医生将装置定向在体内。
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4.发明申请公开(公告)号：US20180333298A1
公开(公告)日：2018-11-22
申请号：US15985468
申请日：2018-05-21
Applicant: California Institute of Technology
Inventor： Yu-Chong Tai , Nicholas Scianmarello , Colin A. Cook
CPC classification number: A61F9/0017 , A61F2240/001 , A61F2250/0068 , B29C39/10 , B29C41/36 , B29K2083/005 , B29L2031/7548
Abstract: An implantable medical device is described. The implantable medical device includes an anti-condensation filler that is highly permeable to a predetermined class of small molecules, such as oxygen. The implantable medical device includes a small molecule discharge bag that is permeable to the small molecule, and a cannula that connects an interior of the small discharge bag to the anti-condensation filler. In operation, small molecules are collected and transported through the anti-condensation filler to the cannula for diffusion through the small molecule discharge bag. Even when this device is implanted in a high humidity and temperature gradient environment, the anti-condensation filler prevents condensation, such as water condensation.
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公开(公告)号：US09919140B2
公开(公告)日：2018-03-20
申请号：US14433583
申请日：2013-10-07
Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA , DOHENY EYE INSTITUTE , CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Mark S. Humayun , Karthik Murali , Ramiro Magalhaes Ribeiro , Yu-chong Tai , Nicholas Scianmarello
CPC classification number: A61M37/00 , A61F9/0017 , A61M5/14276 , A61M2005/14204 , A61M2205/3334 , A61M2210/0612 , C25B1/02 , C25B9/08
Abstract: An implantable oxygenator may have a configuration that is suitable for implantation within a human body be implanted within a human body, such as within a human eye. The implantable oxygenator may include an electrolyte reservoir having a configuration suitable for storing electrolyte and an electrolysis system having a configuration that performs electrolysis on a portion of the electrolyte, thereby producing oxygen in the region of the electrolysis system.
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