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1.发明申请公开(公告)号：US20190127886A1
公开(公告)日：2019-05-02
申请号：US16233544
申请日：2018-12-27
Applicant: Cardiac Pacemakers, Inc.
Inventor： Joseph T. Delaney, JR. , Jeannette C. Polkinghorne , Adegbola O. Adenusi , David R. Wulfman , Kasyap Seethamraju
Abstract: A medical electrical lead includes an insulative lead body extending from a distal region to a proximal region and a conductor disposed within the insulative lead body and extending from the proximal region to the distal region. An electrode is disposed on the insulative lead body and is in electrical contact with the conductor. The medical electrical lead also includes a cross-linked hydrophilic polymer coating disposed over at least a portion of the electrode. The cross-linked hydrophilic polymer coating includes a fibrous matrix comprising a plurality of discrete fibers and pores formed between at least a portion of the fibers and a hydrophilic polyethylene glycol-containing hydrogel network disposed within the pores of the fibrous matrix.
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公开(公告)号：US20160008607A1
公开(公告)日：2016-01-14
申请号：US14790238
申请日：2015-07-02
Applicant: Cardiac Pacemakers, Inc.
Inventor： Michael J. Kane , Joseph Thomas Delaney, JR. , Kasyap Seethamraju
IPC: A61N1/375
CPC classification number: A61N1/3754 , A61N1/362 , H01B3/28 , H01B3/441
Abstract: A method of making a feed-thru connector assembly includes inserting a conductor within an opening within a housing of a pulse generator and dispensing a sealant in a gap between the conductor and portions of the housing adjacent to the conductor that define the opening of the housing and curing the sealant to form a seal comprising a polyisobutylene cross-linked network.
Abstract translation: 一种制造馈通连接器组件的方法包括将导体插入在脉冲发生器的壳体内的开口内，并且在导体与壳体的邻近导体的部分之间的间隙中分配密封剂，该间隙限定壳体的开口 并固化密封剂以形成包含聚异丁烯交联网络的密封件。
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Patent Agency Ranking
公开(公告)号：US11491338B2
公开(公告)日：2022-11-08
申请号：US16206826
申请日：2018-11-30
Applicant: Cardiac Pacemakers, Inc.
Inventor： Michael J. Kane , Joseph T. Delaney, Jr. , Kasyap Seethamraju
Abstract: A method of making a feed-thru connector assembly includes inserting a conductor within an opening within a housing of a pulse generator and dispensing a sealant in a gap between the conductor and portions of the housing adjacent to the conductor that define the opening of the housing and curing the sealant to form a seal comprising a polyisobutylene cross-linked network.
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公开(公告)号：US20190126052A1
公开(公告)日：2019-05-02
申请号：US16206826
申请日：2018-11-30
Applicant: Cardiac Pacemakers, Inc.
Inventor： Michael J. Kane , Joseph T. Delaney, JR. , Kasyap Seethamraju
Abstract: A method of making a feed-thru connector assembly includes inserting a conductor within an opening within a housing of a pulse generator and dispensing a sealant in a gap between the conductor and portions of the housing adjacent to the conductor that define the opening of the housing and curing the sealant to form a seal comprising a polyisobutylene cross-linked network.
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5.发明申请LUBRICIOUS, BIOCOMPATIBLE HYDROPHILIC THERMOSET COATING USING INTERPENETRATING HYDROGEL NETWORKS 审中-公开润滑油，生物易燃水热油漆涂料使用互连氢化网络公开(公告)号：US20150025608A1
公开(公告)日：2015-01-22
申请号：US14329123
申请日：2014-07-11
Applicant: Cardiac Pacemakers, Inc.
Inventor： Joseph T. Delaney, JR. , Jeannette C. Polkinghorne , Adegbola O. Adenusi , David R. Wulfman , Kasyap Seethamraju
CPC classification number: D01D5/0023 , A61N1/05 , A61N1/0534 , A61N1/0541 , A61N1/0543 , A61N1/0551 , A61N1/056 , D01D5/0007
Abstract: A medical electrical lead includes an insulative lead body extending from a distal region to a proximal region and a conductor disposed within the insulative lead body and extending from the proximal region to the distal region. An electrode is disposed on the insulative lead body and is in electrical contact with the conductor. The medical electrical lead also includes a cross-linked hydrophilic polymer coating disposed over at least a portion of the electrode. The cross-linked hydrophilic polymer coating includes a fibrous matrix comprising a plurality of discrete fibers and pores formed between at least a portion of the fibers and a hydrophilic polyethylene glycol-containing hydrogel network disposed within the pores of the fibrous matrix.
Abstract translation: 医用电线包括从远端区域延伸到近端区域的绝缘引线体和设置在绝缘引线主体内并从近端区域延伸到远端区域的导体。 电极设置在绝缘引线体上并与导体电接触。 医用电引线还包括设置在电极的至少一部分上的交联的亲水聚合物涂层。 交联的亲水性聚合物涂层包括纤维基质，其包含多个离散的纤维和形成在纤维的至少一部分之间的孔和设置在纤维基质的孔内的亲水性含聚乙二醇的水凝胶网络。
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6.发明授权公开(公告)号：US11155933B2
公开(公告)日：2021-10-26
申请号：US16233544
申请日：2018-12-27
Applicant: Cardiac Pacemakers, Inc.
Inventor： Joseph T. Delaney, Jr. , Jeannette C. Polkinghorne , Adegbola O. Adenusi , David R. Wulfman , Kasyap Seethamraju
Abstract: A medical electrical lead includes an insulative lead body extending from a distal region to a proximal region and a conductor disposed within the insulative lead body and extending from the proximal region to the distal region. An electrode is disposed on the insulative lead body and is in electrical contact with the conductor. The medical electrical lead also includes a cross-linked hydrophilic polymer coating disposed over at least a portion of the electrode. The cross-linked hydrophilic polymer coating includes a fibrous matrix comprising a plurality of discrete fibers and pores formed between at least a portion of the fibers and a hydrophilic polyethylene glycol-containing hydrogel network disposed within the pores of the fibrous matrix.
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公开(公告)号：US20160122464A1
公开(公告)日：2016-05-05
申请号：US14972317
申请日：2015-12-17
Applicant: Cardiac Pacemakers, Inc.
Inventor： Jan Seppala , Kasyap Seethamraju , Ronald A. Dombro , James Lasch , Paul V. Grosso
CPC classification number: C08G18/73 , C08G18/244 , C08G18/3206 , C08G18/4854 , C08G18/6204 , C08G18/6674 , C08G18/7671
Abstract: A biocompatible polyisobutylene urethane, urea, and urethane/urea copolymer including hard segments, soft segments and that is free of urethane, urea or urethane/urea solvents. The hard include diisocyanate residue. The soft segments include at least one polyisobutylene diol or diamine and optionally a polyether diol.
Abstract translation: 生物相容的聚异丁烯氨基甲酸酯，尿素和氨基甲酸酯/尿素共聚物，包括硬链段，软链段，并且不含氨基甲酸酯，脲或氨基甲酸酯/尿素溶剂。 硬包括二异氰酸酯残基。 软链段包括至少一种聚异丁烯二醇或二胺和任选的聚醚二醇。
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