公开(公告)号：US20240087870A1

公开(公告)日：2024-03-14

申请号：US18273914

申请日：2022-01-21

Applicant: DH Technologies Development Pte. Ltd.

Inventor： Leigh BEDFORD ,  Hassan JAVAHERI ,  Yang KANG ,  Bradley B. SCHNEIDER

IPC: H01J49/24

CPC classification number: H01J49/24

Abstract: In one aspect, an ion guide for use in a mass spectrometry system is disclosed, which comprises an inlet for receiving a plurality of ions entrained in a gas flow, and a plurality of rods arranged in a multipole configuration so as to provide a passageway through which the received ions can traverse. At least one of the rods is configured for application of a DC and/or an RF voltage thereto for generating an electromagnetic field within the passageway suitable for focusing the ions, and a controller configured to maintain an operational pressure of the ion guide within a predefined range.

公开(公告)号：US20230118135A1

公开(公告)日：2023-04-20

申请号：US17913499

申请日：2021-03-19

Applicant: DH Technologies Development Pte. Ltd.

Inventor： Thomas BIESENTHAL ,  Hassan JAVAHERI ,  Bradley B. Schneider

IPC: H01J49/06 ,  H01J49/02 ,  H01J49/24 ,  H01J49/00

Abstract: A mass spectrometer comprises an orifice plate having an orifice, a first multipole ion guide in a first chamber downstream of said orifice plate, said first multipole ion guide comprising a plurality of rods, and a second multipole ion guide in a second chamber downstream of said first chamber, said second multipole ion guide comprising a plurality of rods. A first ion lens is between the first and the second multipole ion guides. A third multipole ion guide is in a third chamber downstream of the second chamber, the third multipole ion guide comprises a plurality of rods. A second ion lens is between the second and third chambers. A tunable DC voltage source applies a tunable DC offset voltage to at least one of the above ion guide and ion lenses to increase an axial kinetic energy of the ions to cause at least one of declustering and/or fragmentation.