公开(公告)号：US20240297028A1

公开(公告)日：2024-09-05

申请号：US18589559

申请日：2024-02-28

Applicant: DH Technologies Development Pte. Ltd.

Inventor： Scott DANIELS ,  Aaron STELLA ,  Michal WEINSTOCK

IPC: H01J49/00 ,  G06F3/0484

CPC classification number: H01J49/0009 ,  G06F3/0484

Abstract: A method for calibrating a mass spectrometry (MS) system includes: receiving at least one input through a corresponding to a calibrator in a sample, wherein the sample includes an analyte, and wherein the sample is analyzed by the MS system; automatically determining a plurality of transitions in the sample corresponding to the calibrator according to natural abundances of isotopes; automatically determining concentrations of the plurality of transitions according to a concentration of the calibrator in the sample; identifying a plurality of transitions as calibrator transitions and for identifying a different one of the plurality of transitions as an internal standard; detecting a concentration of each of the plurality of transitions and the calibrator in the sample; automatically calibrating the MS system based in part on the detected concentrations of the plurality of calibrator transitions and the internal standard; and detecting the concentration of the analyte in response to execution of the calibration instructions.