公开(公告)号：US11034963B2

公开(公告)日：2021-06-15

申请号：US16347935

申请日：2017-11-08

Applicant: DOTS Technology Corp.

Inventor： Adi Gilboa-Geffen ,  Valerie Villareal ,  Sarah Stidham ,  Morris Nehama

IPC: C12N15/115 ,  C12N15/10 ,  G01N33/02 ,  G01N33/533 ,  C12Q1/6816

Abstract: The present application discloses nucleic acid aptamer based signaling polynucleotides (SPNs) that specifically bind an allergen protein. Provided in the present invention include aptamers, SPNs, SPN-complement complexes, magnetic particle conjugates, DNA printed glass slides and detection agents, and detection methods using the same for detecting the presence, or absence of an allergen protein in a food sample.

公开(公告)号：US20190292544A1

公开(公告)日：2019-09-26

申请号：US16347935

申请日：2017-11-08

Applicant: DOTS Technology Corp.

Inventor： Adi Gilboa-Geffen ,  Valerie Villareal ,  Sarah Stidham ,  Morris Nehama

IPC: C12N15/115 ,  G01N33/02 ,  C12N15/10 ,  G01N33/533

Abstract: The present application discloses nucleic acid aptamer based signaling polynucleotides (SPNs) that specifically bind an allergen protein. Provided in the present invention include aptamers, SPNs, SPN-complement complexes, magnetic particle conjugates, DNA printed glass slides and detection agents, and detection methods using the same for detecting the presence, or absence of an allergen protein in a food sample.