公开(公告)号：US20170098532A1

公开(公告)日：2017-04-06

申请号：US15231592

申请日：2016-08-08

Applicant: Fluidigm Canada Inc.

Inventor： RAYMOND JONG

IPC: H01J49/04 ,  G01N15/10 ,  H01J49/10

CPC classification number: H01J49/0445 ,  G01N15/06 ,  G01N15/10 ,  G01N35/10 ,  G01N2015/0065 ,  G01N2015/1006 ,  H01J49/045 ,  H01J49/105

Abstract: In a mass cytometer or mass spectrometer, a sample of elemental tagged particles is transferred from a dispersion to a gas flow through a carrier aerosol spray for atomization and ionization by inductively coupled plasma (ICP) source. The configuration of the sample transfer apparatus allow for total consumption of the sample by passing the sample spray through a deceleration stage to decelerate the spray of particles from its high velocity expansion. Following the deceleration stage, the decelerated sample of particles can be accelerated and focused through an acceleration stage for transferring into the ICP. This effectively improves the particle transfer between the sample spray and the ICP.

公开(公告)号：US20150122991A1

公开(公告)日：2015-05-07

申请号：US14594319

申请日：2015-01-12

Applicant: FLUIDIGM CANADA INC.

Inventor： RAYMOND JONG

IPC: H01J49/04 ,  G01N35/10 ,  H01J49/10

CPC classification number: H01J49/0445 ,  G01N15/06 ,  G01N15/10 ,  G01N35/10 ,  G01N2015/0065 ,  G01N2015/1006 ,  H01J49/045 ,  H01J49/105

Abstract: In a mass cytometer or mass spectrometer, a sample of elemental tagged particles is transferred from a dispersion to a gas flow through a carrier aerosol spray for atomization and ionization by inductively coupled plasma (ICP) source. The configuration of the sample transfer apparatus allow for total consumption of the sample by passing the sample spray through a deceleration stage to decelerate the spray of particles from its high velocity expansion. Following the deceleration stage, the decelerated sample of particles can be accelerated and focused through an acceleration stage for transferring into the ICP. This effectively improves the particle transfer between the sample spray and the ICP.

Abstract translation: 在质谱仪或质谱仪中，将元素标记的颗粒的样品从分散体转移到通过载体气溶胶喷雾的气流中，以通过电感耦合等离子体（ICP）源进行雾化和电离。 样品转印装置的结构允许通过使样品喷雾通过减速阶段来使样品总消耗，以使颗粒从其高速膨胀中的喷雾减速。 在减速阶段后，减速的颗粒样品可以通过加速阶段加速和聚焦，以转移到ICP中。 这有效地改善了样品喷雾和ICP之间的颗粒转移。