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1.
公开(公告)号:US20240355686A1
公开(公告)日:2024-10-24
申请号:US18759691
申请日:2024-06-28
Applicant: Daniel Pierce RADIN
Inventor: Daniel Pierce RADIN
CPC classification number: H01L22/12 , G01N21/94 , G01N21/9501 , H01J49/0036 , H01J49/0422 , H01J49/105
Abstract: Disclosed herein are compositions and methods employing AMPA Receptor (AMPR) antagonist compounds to treat AMPAR positive cancers in mammalian subjects. In certain detailed embodiments the AMPAR antagonist is a Perampanel compound, effective to mediate potent oncolytic effects to prevent or reduce the severity or recurrence of a variety of cancer forms, including central nervous system (CNS) cancers.
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公开(公告)号:US12107016B2
公开(公告)日:2024-10-01
申请号:US17196116
申请日:2021-03-09
Applicant: Zing Semiconductor Corporation
Inventor: Lanlin Wen , Tian Feng , Zhen Zhou
IPC: H01L21/225 , H01J49/00 , H01J49/10 , H01L21/66
CPC classification number: H01L22/10 , H01J49/0031 , H01J49/105 , H01L21/2252 , H01L22/12
Abstract: The present application provides a detection method of metal impurity in wafer. The method comprises conducting a medium temperature thermal treatment for a first predicted time period to the wafer, cooling the wafer and conducting a low temperature thermal treatment for a second predicted time period, cooling the wafer to ambient temperature; providing a liquid of vapor phase decomposition on the wafer to collect metal impurities; atomizing the liquid containing the collected metal impurities, conducting an inductively coupled plasma mass spectrometry analysis and obtaining concentrations of the metal impurities. The present application applies the combination of various thermal treatment without an interrupt of cooling to ambient temperature to contemplate diffusions of various metal impurities to the wafer surface. Accordingly, the detection of metal impurities can be conducted with reduced time cost and enhanced efficiency.
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公开(公告)号:US12087567B2
公开(公告)日:2024-09-10
申请号:US18339510
申请日:2023-06-22
Applicant: Thermo Fisher Scientific (Bremen) GmbH
Inventor: Henning Wehrs , Johannes Schwieters , Gerhard Jung
CPC classification number: H01J49/063 , F16K1/2007 , H01J49/005 , H01J49/0077 , H01J49/022 , H01J49/065 , H01J49/067 , H01J49/068 , H01J49/105 , H01J49/421 , H01J49/4215
Abstract: An ion optical arrangement (1) for use in a mass spectrometer comprises electrodes (11, 12, 14) comprising a multipole arrangement defining an ion optical axis, and a voltage source for providing voltages to the electrodes to produce electric fields. The ion optical arrangement is configured for producing a radio frequency electric focusing field for focusing ions on the ion optical axis. The radio frequency electric focusing field has a varying frequency so as to reduce any mass dependence of ion trajectories through the ion optical arrangement. The ion optical arrangement may further be configured for producing a static electric field in response to a DC bias voltage applied to the multipole arrangement. A superimposed varying electric field may be produced by superimposing an AC voltage upon the DC bias voltage.
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公开(公告)号:US12055530B2
公开(公告)日:2024-08-06
申请号:US17125222
申请日:2020-12-17
Applicant: Elemental Scientific, Inc.
Inventor: Alexander Lang , Brianna Dufek , Daniel R. Wiederin
CPC classification number: G01N30/724 , H01J49/0036 , H01J49/0422 , H01J49/045 , H01J49/105 , H01J49/40
Abstract: An embodiment of an analysis system can include an initial multi-port valve, at least one intermediate multi-port valve, a further multi-port valve, and a time-of-flight mass spectrometer (TOF-MS). The initial multi-port valve can be configured to receive a sample. The at least one intermediate multi-port valve can be fluidly connected to the initial multi-port valve and configured to receive the sample from the initial multi-port valve. A given intermediate multi-port valve can have an ion-exchange column associated therewith. The given intermediate multi-port valve can be configured selectably to one of direct the sample through the ion-exchange column associated therewith (in a speciation mode) or bypass the ion-exchange column (in an infusion mode). The further multi-port valve can be fluidly connected with the at least one intermediate multi-port valve and configured to receive the sample from therefrom. The time-of-flight mass spectrometer (TOF-MS) can be fluidly connected to the further multi-port valve.
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公开(公告)号:US12013391B2
公开(公告)日:2024-06-18
申请号:US16383241
申请日:2019-04-12
Applicant: Fluidigm Canada Inc.
Inventor: Vladimir Baranov , Alexander Loboda , Michael Sullivan
CPC classification number: G01N33/5306 , G01N33/58 , H01J49/105 , G01N2458/15 , G01N2560/00
Abstract: Analyzing samples injected into an inductively coupled plasma source can be improved by one or more of a stabilizing solution mixable with a sample prior to injection and a heated injector. The stabilizing solution can minimize the difference in osmotic pressure between the solution and the cells with a relatively low amount of dissolved solids (e.g., at or below about 0.2%). The stabilizing solution can contain a salt (e.g., ammonium nitrate) present in concentrations of at least 5 mM. The injector can be heated before and/or during injection. In some cases, heat from adjacent parts can be channeled into the injector to improve heating of the injector. An injector heated to sufficient temperatures can minimize solute buildup and can extend the usable time between cleanings. These improvements can be especially useful in elemental analysis, such as inductively coupled plasma mass spectrometry or inductively coupled plasma optical emission spectrometry.
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公开(公告)号:US11961730B2
公开(公告)日:2024-04-16
申请号:US17912226
申请日:2021-03-29
Applicant: ATONARP INC.
Inventor: Naoki Takahashi
CPC classification number: H01J49/105 , H05H1/30 , H01J49/4215
Abstract: A plasma generating device includes: a chamber which is equipped with a dielectric wall structure and into which sample gas to be measured flows; an RF supplying mechanism that generates plasma inside the chamber using an electric field and/or a magnetic field through the dielectric wall structure; and a floating potential supplying mechanism that includes a first electrode disposed along an inner surface of the chamber. The RF supplying mechanism may include an RF field forming unit disposed in a first direction with respect to the chamber and the first electrode may include an electrode disposed in a second direction with respect to the chamber.
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公开(公告)号:US11923184B2
公开(公告)日:2024-03-05
申请号:US17644073
申请日:2021-12-13
Applicant: Plasmion GmbH
Inventor: Jan-Christoph Wolf
CPC classification number: H01J49/105 , H01J27/02 , H01J37/08 , H01J37/32348 , H01J49/0031
Abstract: The present invention discloses an ionization apparatus 10 for ionizing an analyte S, comprising an inlet E, an outlet A, a first electrode 1, a second electrode 2 and a dielectric element 3. The first electrode 1, the second electrode 2 and the dielectric element 3 are arranged relative to one another such that, by applying an electric voltage between the first electrode 1 and the second electrode 2, a dielectric barrier discharge is establishable in a discharge area 5 in the ionization apparatus 10. The first and second electrodes 1, 2 are arranged such that they are displaceable or movable relative to each other.
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8.
公开(公告)号:US11921098B2
公开(公告)日:2024-03-05
申请号:US18128583
申请日:2023-03-30
Applicant: Eion Corp.
Inventor: Adam Wolf , Elliot Suk-Hyun Chang , Alan Robert Tank
CPC classification number: G01N33/24 , C09K11/77 , C09K17/12 , H01J49/105
Abstract: The present disclosure relates to methods of verifying enhanced rock weathering using immobile trace elements found within a mineral amendment. Further disclosed are mineral amendments that enable enhanced rock weathering.
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公开(公告)号:US20240053319A1
公开(公告)日:2024-02-15
申请号:US17819562
申请日:2022-08-12
Applicant: SAUDI ARABIAN OIL COMPANY
Inventor: Fatai A. Anifowose , Maimona Washie
CPC classification number: G01N33/24 , G01N25/20 , H01J49/105 , G01N23/223 , G01V11/00 , E21B44/00 , E21B49/02 , G01N2223/076 , G01N2223/616
Abstract: A system and method for determining a net source rock thickness is disclosed. The method includes obtaining at least one well log, a first and second plurality of core samples from a wellbore, and for each of the first plurality determining a relative abundance of inorganic materials, and for each of the second plurality a set of organic material data. The method further includes determining a validated total organic content and a measured source rock thickness based on the organic material data and relative abundance of inorganic materials and determining a data and a prediction portion of the wellbore, based on the second plurality sample locations. The method still further includes determining a cut-off value for each well log, predicting a source rock thickness from the cut-off values and the net source rock thickness from a sum of the predicted and the measured source rock thicknesses.
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公开(公告)号:US11887832B2
公开(公告)日:2024-01-30
申请号:US17703899
申请日:2022-03-24
Applicant: Thermo Fisher Scientific (Bremen) GmbH
Inventor: Johannes Schwieters , Gerhard Jung
CPC classification number: H01J49/288 , H01J49/067 , H01J49/105
Abstract: An isotope ratio mass spectrometer has an ion source, a static field mass filter, a reaction cell to induce a mass shift reaction, and a sector field mass analyser for spatially separating ions from the reaction cell according to their m/z. A detector platform detects a plurality of different ion species separated by the sector field mass analyser. The static field mass filter has a first Wien filter that deflects ions away from a longitudinal symmetry axis of the spectrometer in accordance with the ions' m/z, and a second Wien filter that deflects ions back towards the longitudinal symmetry axis in accordance with the ions' m/z. An inverting lens is positioned along the longitudinal axis between the Wien filters to invert the direction of deflection of the ions from the first Wien filter. The static field mass filter provides high transmission and improved spectrometer sensitivity. The first and second Wien filters permit simple tuning.
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