公开(公告)号：US20180105638A1

公开(公告)日：2018-04-19

申请号：US15707880

申请日：2017-09-18

Applicant: GenapSys, Inc.

Inventor： Aldrich N.K. Lau ,  Paul M. Kenney ,  Henrik Persson

IPC: C08G61/12 ,  C12Q1/6874 ,  C40B50/18 ,  C12Q1/6806 ,  B01J19/00 ,  C12Q1/6834

CPC classification number: C08G61/12 ,  B01J19/0046 ,  B01J2219/005 ,  B01J2219/00563 ,  B01J2219/00648 ,  C12Q1/6806 ,  C12Q1/6834 ,  C12Q1/6874 ,  C40B50/18 ,  C12Q2535/122 ,  C12Q2563/155

Abstract: Provided herein are methods that comprise providing polymer chains comprising a plurality of reactive groups onto the surface of beads and covalent attachment of functionalized biomolecules, such as primers.

公开(公告)号：US10683389B2

公开(公告)日：2020-06-16

申请号：US15707880

申请日：2017-09-18

Applicant: GenapSys, Inc.

Inventor： Aldrich N. K. Lau ,  Paul M. Kenney ,  Henrik Persson

IPC: C08G61/12 ,  C12Q1/6806 ,  C40B50/18 ,  B01J19/00 ,  C12Q1/6834 ,  C12Q1/6874

Abstract: Provided herein are methods that comprise providing polymer chains comprising a plurality of reactive groups onto the surface of beads and covalent attachment of functionalized biomolecules, such as primers.

公开(公告)号：US20180100190A1

公开(公告)日：2018-04-12

申请号：US15655616

申请日：2017-07-20

Applicant: GenapSys, Inc.

Inventor： Hesaam Esfandyarpour ,  Aldrich N.K. Lau ,  Kosar Parizi ,  Saurabh Paliwal ,  Henrik Persson ,  Seth Stern ,  Paul Kenney ,  Meysam R. Barmi ,  Ali Nabi ,  Hamid Rategh ,  Florian Oberstrass

IPC: C12Q1/6869

Abstract: Provided herein are systems and methods for processing and analyzing nucleic acids and other biomolecules. Methods may include processing nucleic acid molecules in an emulsion of droplets. Methods of analyzing nucleic acid molecules may include coupling nucleic acids to a bead or other support. Methods may include analysis of nucleic acid molecules using a redox mediator. In some cases, analysis of the nucleic acid molecule includes determining a nucleotide sequence of the nucleic acid molecule.