公开(公告)号：US20200255893A1

公开(公告)日：2020-08-13

申请号：US16598591

申请日：2019-10-10

Applicant: GenapSys, Inc.

Inventor： Hesaam Esfandyarpour ,  Kosar Baghbani Parizi ,  Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  Susanne Baumhueter ,  Cheryl Heiner ,  Frank Lee

IPC: C12Q1/6874 ,  B01L3/00

Abstract: The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices.

公开(公告)号：US20180245150A1

公开(公告)日：2018-08-30

申请号：US15896572

申请日：2018-02-14

Applicant: GenapSys, Inc.

Inventor： Hesaam Esfandyarpour ,  Kosar Baghbani Parizi ,  Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  Susanne Baumhueter ,  Cheryl Heiner ,  Frank Lee

IPC: C12Q1/6874

Abstract: The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices.

公开(公告)号：US10260095B2

公开(公告)日：2019-04-16

申请号：US16007829

申请日：2018-06-13

Applicant: GenapSys, Inc.

Inventor： Hesaam Esfandyarpour ,  Kosar Baghbani Parizi ,  Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  Susanne Baumhueter ,  Cheryl Heiner ,  Frank Lee

IPC: C12Q1/68 ,  C12Q1/6874 ,  G01N27/327 ,  G01N33/543

Abstract: The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices.

公开(公告)号：US11155865B2

公开(公告)日：2021-10-26

申请号：US16039016

申请日：2018-07-18

Applicant: GenapSys, Inc.

Inventor： Hesaam Esfandyarpour ,  Kosar Baghbani Parizi ,  Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  Susanne Baumhueter ,  Cheryl Heiner ,  Frank Lee

IPC: C12Q1/68 ,  C12Q1/6874 ,  G01N27/327 ,  G01N33/543 ,  B01L3/00

Abstract: The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices.

公开(公告)号：US11021748B2

公开(公告)日：2021-06-01

申请号：US16598591

申请日：2019-10-10

Applicant: GenapSys, Inc.

Inventor： Hesaam Esfandyarpour ,  Kosar Baghbani Parizi ,  Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  Susanne Baumhueter ,  Cheryl Heiner ,  Frank Lee

IPC: C12Q1/68 ,  B01L3/00 ,  C12Q1/6874 ,  G01N27/327 ,  G01N33/543

Abstract: The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices.

公开(公告)号：US20180282806A1

公开(公告)日：2018-10-04

申请号：US16007969

申请日：2018-06-13

Applicant: GenapSys, Inc.

Inventor： Hesaam Esfandyarpour ,  Kosar Baghbani Parizi ,  Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  Susanne Baumhueter ,  Cheryl Heiner ,  Frank Lee

IPC: C12Q1/6874

CPC classification number: C12Q1/6874 ,  G01N27/327 ,  G01N33/54313 ,  G01N33/5438 ,  C12Q2527/119 ,  C12Q2563/116 ,  C12Q2565/607 ,  C12Q2549/126

Abstract: The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices.

公开(公告)号：US10787705B2

公开(公告)日：2020-09-29

申请号：US15896572

申请日：2018-02-14

Applicant: GenapSys, Inc.

Inventor： Hesaam Esfandyarpour ,  Kosar Baghbani Parizi ,  Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  Susanne Baumhueter ,  Cheryl Heiner ,  Frank Lee

IPC: C12Q1/68 ,  C12Q1/6874 ,  G01N27/327 ,  G01N33/543

Abstract: The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices.

公开(公告)号：US10266892B2

公开(公告)日：2019-04-23

申请号：US16007969

申请日：2018-06-13

Applicant: GenapSys, Inc.

Inventor： Hesaam Esfandyarpour ,  Kosar Baghbani Parizi ,  Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  Susanne Baumhueter ,  Cheryl Heiner ,  Frank Lee

IPC: C12Q1/68 ,  C12Q1/6874 ,  G01N27/327 ,  G01N33/543

Abstract: The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices.

公开(公告)号：US09274077B2

公开(公告)日：2016-03-01

申请号：US13838816

申请日：2013-03-15

Applicant: GenapSys, Inc.

Inventor： Hesaam Esfandyarpour ,  Kosar Baghbani Parizi ,  Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  Susanne Baumhueter ,  Cheryl Heiner ,  Frank Lee

IPC: G01N27/327 ,  G01N33/543

CPC classification number: C12Q1/6874 ,  G01N27/327 ,  G01N33/54313 ,  G01N33/5438 ,  C12Q2527/119 ,  C12Q2563/116 ,  C12Q2565/607 ,  C12Q2549/126

Abstract: The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices.

Abstract translation: 本发明涉及用于测序多核苷酸的系统和方法，以及检测涉及其它生物分子的反应和结合事件。 该系统和方法可以采用无室装置和纳米传感器来检测或表征高通量的这种反应。 因为在许多实施例中的系统是可重复使用的，与单次使用设备相比，该系统可以经受更复杂和改进的工程。

公开(公告)号：US20190177791A1

公开(公告)日：2019-06-13

申请号：US16283544

申请日：2019-02-22

Applicant: GenapSys, Inc.

Inventor： Hesaam Esfandyarpour ,  Kosar Baghbani Parizi ,  Mark F. Oldham ,  Eric S. Nordman ,  Richard T. Reel ,  Susanne Baumhueter ,  Cheryl Heiner ,  Frank Lee

IPC: C12Q1/6874 ,  G01N33/543 ,  G01N27/327

Abstract: The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices.