公开(公告)号：US20160025659A1

公开(公告)日：2016-01-28

申请号：US14774367

申请日：2014-01-22

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Yusuke OMINAMI ,  Mitsugu SATO ,  Kenko UCHIDA ,  Sadamitsu ASO ,  Taku SAKAZUME ,  Hideo MORISHITA ,  Sukehiro ITO ,  Takashi OHSHIMA

IPC: G01N23/225 ,  G01N23/22

CPC classification number: G01N23/2251 ,  G01N23/2204 ,  H01J37/20 ,  H01J37/244 ,  H01J37/28 ,  H01J2237/2003 ,  H01J2237/2443 ,  H01J2237/2445 ,  H01J2237/24455 ,  H01J2237/2605

Abstract: The purpose of the present invention is to eliminate the effort in placement and extraction of samples in observations using transmitted charged particles. A charged particle beam device (601) is characterized by having: a charged particle optical lens tube that irradiates a sample (6) with a primary charged particle beam; a sample stage on which a light emitting member (500) that emits light because of charged particles that have come by transmission internally in the sample (6) or scattering therefrom or a sample platform (600) having the light emitting member (500) is attachably and detachably disposed; and a detector (503) that detects the light emitted by the light emitting member.

Abstract translation: 本发明的目的是消除在使用透射带电粒子的观察中放置和提取样品的努力。 带电粒子束装置（601）的特征在于，具有：带有原色带电粒子束照射样品（6）的带电粒子光学透镜管; 具有发光元件（500）的样品台，其上由于在样品（6）内部传播或散射的带电粒子或具有发光元件（500）的样品台（600）而发光的发光元件 可拆卸地设置; 以及检测由发光部件发出的光的检测器（503）。

公开(公告)号：US20200151877A1

公开(公告)日：2020-05-14

申请号：US16603445

申请日：2018-02-26

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hideharu HATTORI ,  Yasuki KAKISHITA ,  Kenko UCHIDA ,  Sadamitsu ASO ,  Toshinari SAKURAI

IPC: G06T7/00 ,  G06K9/46

Abstract: An image diagnosis assisting apparatus according to the present invention executes: processing of inputting an image of a tissue or cell; processing of extracting a feature amount of a tissue or cell from a processing target image; processing of extracting a feature amount of a tissue or cell from an image having a component different from that of the target image; and processing of determining presence or absence of a lesion and lesion probability for each of the target images by using a plurality of the feature amounts.

公开(公告)号：US20190041359A1

公开(公告)日：2019-02-07

申请号：US16083780

申请日：2016-03-18

Applicant: Hitachi High-Technologies Corporation

Inventor： Taro NAKAZAWA ,  Motohiro YAMAZAKI ,  Kenko UCHIDA ,  Akira FUJII

IPC: G01N27/447

Abstract: A capillary electrophoresis apparatus is disclosed that does not discharge and achieves both compactness and performance even with a part configuration having insufficient spatial distance or creeping distance. This capillary electrophoresis apparatus is provided with a resistance heater for heating capillaries, an electrode holder that holds capillary electrodes and is connected to a high-voltage unit, and a conductive member that at least partially comprises metal and has been grounded to a low potential. The electrode holder and conductive member are in contact with heat-dissipating rubber disposed there between that composes a structure comprising an insulation member. As a result of this configuration, discharge risk is reduced through the reduction of the potential of parts near the high-voltage unit and the slow reduction of the high potential of the high-voltage unit.

公开(公告)号：US20180265918A1

公开(公告)日：2018-09-20

申请号：US15775408

申请日：2015-12-01

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Masataka SHIRAI ,  Tomoyuki SAKAI ,  Kenko UCHIDA

IPC: C12Q1/6837 ,  C12Q1/6809 ,  C12N15/10 ,  C40B40/08 ,  C40B50/06 ,  G01N33/543

CPC classification number: C12Q1/6837 ,  C12N15/1003 ,  C12N15/1093 ,  C12N15/1096 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/6809 ,  C40B40/08 ,  C40B50/06 ,  G01N33/54306

Abstract: The purpose of the present invention is to provide a single cell analysis device in which the improvement of the nucleic acid capturing efficiency and the improvement of the cell capturing efficiency are both achieved and a highly accurate single cell analysis data is thereby obtained. The present invention relates to an improvement of a cell analysis device including a two-dimensional array chip having a plurality of cell capture parts capable of capturing a single cell in each of the capture parts, and nucleic acid capture parts corresponding to the respective cell capture parts, the nucleic acid capture parts being capable of capturing a nucleic acid extracted from the cell captured by the cell capture part.

公开(公告)号：US20180053296A1

公开(公告)日：2018-02-22

申请号：US15556546

申请日：2016-01-28

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hideharu HATTORI ,  Yasuki KAKISHITA ,  Kenko UCHIDA ,  Sadamitsu ASO ,  Fumiaki HAMAZATO

IPC: G06T7/00 ,  G01N33/483 ,  G06K9/46 ,  G06K9/62

Abstract: The present invention realizes determination of tissues and cells from an image by calculating feature values of a deformed degree of the cells even in a case where the tissues or the cells have various shapes. An image diagnosis support apparatus according to the present invention executes processing of inputting an image of cells, processing of extracting the feature values of a plurality of direction components from a target image of the processing, processing of determining whether or not the image corresponds to one-classification by using the plurality of feature values, and processing of determining whether or not the determination processing is finished with respect to all of the classifications set in advance (FIG. 1).

公开(公告)号：US20190236779A1

公开(公告)日：2019-08-01

申请号：US16340401

申请日：2017-10-26

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Hideharu HATTORI ,  Kenko UCHIDA ,  Sadamitsu ASO ,  Toshinari SAKURAI ,  Yasuki KAKISHITA

IPC: G06T7/00 ,  G06K9/00 ,  G06T1/00 ,  G16H30/40 ,  G16H50/20

CPC classification number: G06T7/0012 ,  G01N15/00 ,  G01N33/48 ,  G06K9/00147 ,  G06T1/0007 ,  G06T2207/10056 ,  G06T2207/20081 ,  G06T2207/30024 ,  G06T2207/30096 ,  G16H30/40 ,  G16H50/20

Abstract: A diagnostic imaging assistance apparatus according to the present invention performs a process of inputting images of a tissue and a cell, a process of extracting feature amounts of a wide view and a narrow view from a target image to be processed, a process of classifying whether the target images having different views are normal or abnormal from the feature amounts, and a process of classifying a lesion likelihood using a classification result.

公开(公告)号：US20190172206A1

公开(公告)日：2019-06-06

申请号：US16323808

申请日：2017-08-28

Applicant: Hitachi High-Technologies Corporation

Inventor： Yasuki KAKISHITA ,  Hideharu HATTORI ,  Kenko UCHIDA ,  Sadamitsu ASO ,  Toshinari SAKURAI

IPC: G06T7/00 ,  G06K9/00 ,  G06T7/11

Abstract: Reaction values indicating based on which areas in an input image a plurality of identification results representing the states of cells or tissues are judged are calculated, and differences between a plurality of reaction values are obtained to thereby calculate the degree to which cells or tissues in an area of interest likely are in each state. Thereby, each state of cells or tissues can be visualized at an accurate position in an area of interest; therefore, diagnostic assistance to pathologist becomes possible.

公开(公告)号：US20180220944A1

公开(公告)日：2018-08-09

申请号：US15579957

申请日：2016-04-27

Applicant: Hitachi High-Technologies Corporation

Inventor： Ayano OTSUBO ,  Yoshihiro NAGAOKA ,  Taku SAKAZUME ,  Kenko UCHIDA ,  Shigenori TOGASHI

IPC: A61B5/15

Abstract: A blood collecting device collects blood in a short time after puncture without scattering the blood into the open air other than a container for collecting the blood. One of representative blood collecting devices has a container unit that includes a screw portion, a holder that holds the container unit serving as a system whose one end is closed, a puncture unit that can be attached to the container or the holder, a through-hole of the puncture unit, and a puncture unit protection member that protects the puncture unit and the container unit.