公开(公告)号：US20120225457A1

公开(公告)日：2012-09-06

申请号：US13294596

申请日：2011-11-11

Applicant: June-young LEE ,  Jwa-min NAM ,  Su-hyeon KIM ,  Woo-chang LEE ,  Jae-young KIM ,  Joo-won RHEE ,  Young-kwang LEE ,  Dong-kwon LIM ,  Jae-ho HWANG

Inventor： June-young LEE ,  Jwa-min NAM ,  Su-hyeon KIM ,  Woo-chang LEE ,  Jae-young KIM ,  Joo-won RHEE ,  Young-kwang LEE ,  Dong-kwon LIM ,  Jae-ho HWANG

IPC: C12P19/34 ,  B32B5/16 ,  C07H21/00 ,  B82Y99/00

CPC classification number: C07H21/00 ,  B82Y15/00 ,  C12P19/34 ,  Y10T428/2991

Abstract: A nanoparticle-nucleic acid complex and a method of linearizing a target nucleic acid by using the nanoparticle-nucleic acid complex are disclosed. By using the nanoparticle-nucleic acid complex and the method, nucleotide sequence analysis and mapping of a target nucleic acid may be efficiently performed.

Abstract translation: 公开了纳米颗粒 - 核酸复合物和通过使用纳米颗粒 - 核酸复合物线性化靶核酸的方法。 通过使用纳米粒子 - 核酸复合物和该方法，可以有效地进行目标核酸的核苷酸序列分析和作图。

公开(公告)号：US20120064510A1

公开(公告)日：2012-03-15

申请号：US13224540

申请日：2011-09-02

Applicant: Joo-won RHEE ,  Su-hyeon KIM

Inventor： Joo-won RHEE ,  Su-hyeon KIM

IPC: G01N33/53 ,  G01N21/64 ,  G01N21/75 ,  C12Q1/70 ,  C12Q1/68

CPC classification number: C12Q1/6827 ,  G01N21/6428 ,  G01N33/5308 ,  G01N33/542 ,  G01N2021/6441 ,  C12Q2522/101 ,  C12Q2563/107 ,  C12Q2563/119

Abstract: A kit including a target sequence-binding protein and a method of detecting a target nucleic acid by using the kit that may ensure efficient detection of the target nucleic acid in a biological sample are disclosed.

Abstract translation: 公开了一种试剂盒，其包括靶序列结合蛋白和通过使用试剂盒检测靶核酸的方法，所述试剂盒可以确保生物样品中靶核酸的有效检测。

公开(公告)号：US20080182310A1

公开(公告)日：2008-07-31

申请号：US12059250

申请日：2008-03-31

Applicant: Su-hyeon KIM ,  Jeong-gun LEE

Inventor： Su-hyeon KIM ,  Jeong-gun LEE

IPC: C12N13/00

CPC classification number: C12M47/06 ,  B01L3/5027 ,  C12N1/066 ,  C12N13/00 ,  G01N1/44 ,  Y10T137/2496 ,  Y10T436/25

Abstract: A cell lysis device for lysing cells or viruses, comprising a cell lysis tube having a sample inlet; a pump connected to the cell lysis tube for transferring a sample into the tube; a sealing unit for reversibly sealing a specific region of the tube; and a laser source for generating a laser is provide. Further, a method of lysing cells or viruses using the cell lysis device is provide. The method comprises introducing a sample containing cells or viruses and optionally magnetic beads to the cell lysis tube through the sample inlet; transferring the sample to a specific region in the cell lysis tube by means of the pump; temporarily sealing the region of the cell lysis tube where the sample is placed with the sealing unit; irradiating the sample with the laser; removing the sealing unit from the cell lysis tube; and discharging the sample from the cell lysis tube by means of the pump.

公开(公告)号：US20100204065A1

公开(公告)日：2010-08-12

申请号：US12762596

申请日：2010-04-19

Applicant: Su-hyeon KIM ,  In-ho LEE ,  Jun-hong MIN

Inventor： Su-hyeon KIM ,  In-ho LEE ,  Jun-hong MIN

IPC: C40B50/14

CPC classification number: B82Y30/00 ,  B01J19/0046 ,  B01J2219/00369 ,  B01J2219/00432 ,  B01J2219/005 ,  B01J2219/0052 ,  B01J2219/00641 ,  B01J2219/00644 ,  B01J2219/00657 ,  B01J2219/00673 ,  B01J2219/00677 ,  B01J2219/00711 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00729 ,  B01J2219/00743

Abstract: A microarray including hydrogel and a plurality of probes which are immobilized in discrete regions of the hydrogel, and a method of preparing the same are provided. When using the microarray and method, a solid substrate is not required and many biomolecules can be immobilized in a small volume, thereby obtaining high sensitivity. Since gel can be cut to obtain many pieces, many microarrays can be prepared at once.

Abstract translation: 提供了包含水凝胶和固定在水凝胶的离散区域中的多个探针的微阵列及其制备方法。 当使用微阵列和方法时，不需要固体底物，并且许多生物分子可以以小体积固定，从而获得高灵敏度。 由于可以切割凝胶以获得许多片，因此可以一次制备许多微阵列。

公开(公告)号：US20090099782A1

公开(公告)日：2009-04-16

申请号：US12128680

申请日：2008-05-29

Applicant: Su-hyeon KIM ,  Yoon-kyoung CHO ,  Jeong-gun LEE

Inventor： Su-hyeon KIM ,  Yoon-kyoung CHO ,  Jeong-gun LEE

IPC: G01N33/50

CPC classification number: G01N35/00732 ,  G01N35/00069 ,  G01N35/08 ,  G01N2035/00752 ,  Y10T436/11

Abstract: Provided are an automatic analyzing method and apparatus for a microfludic system. The apparatus includes means for recognizing a disc or chip in the microfludic system, performs an operation and detection by automatically loading a DB according to a recognized type, and perform quantitation of a test.

Abstract translation: 本发明提供一种微流体系统的自动分析方法和装置。 该装置包括用于识别微流体系统中的盘或芯片的装置，通过根据识别的类型自动加载数据库进行操作和检测，并执行测试的定量。

公开(公告)号：US20120220473A1

公开(公告)日：2012-08-30

申请号：US13303813

申请日：2011-11-23

Applicant: Tae-jin AHN ,  Su-hyeon KIM ,  Kyoung-gu WOO

Inventor： Tae-jin AHN ,  Su-hyeon KIM ,  Kyoung-gu WOO

IPC: C40B30/04 ,  G06F19/00

CPC classification number: G06F19/16

Abstract: An efficient and accurate method of identifying a target biomolecule in a sample by using target molecule-probe binding frequencies is disclosed.

Abstract translation: 公开了通过使用靶分子 - 探针结合频率来鉴定样品中的靶生物分子的有效和准确的方法。

公开(公告)号：US20110046019A1

公开(公告)日：2011-02-24

申请号：US12702381

申请日：2010-02-09

Applicant: Su-hyeon KIM

Inventor： Su-hyeon KIM

IPC: C40B50/18 ,  C40B60/14

CPC classification number: G01N33/54353

Abstract: A method for immobilizing a target material on a substrate includes applying a voltage across a first solution including the target material in contact with a surface of a film including a pore disposed therein, a second solution in contact with an opposite surface of the film, and a substrate disposed facing the opposite surface of the film, moving the target material from the first solution, through the pore of the film into the second solution, and immobilizing the target material on the substrate.

Abstract translation: 将目标材料固定在基板上的方法包括在包括目标材料的第一溶液上施加电压，所述第一溶液与包括设置在其中的孔的膜的表面接触，与膜的相对表面接触的第二溶液，以及 面向所述膜的相对表面的基板，将所述目标材料从所述第一溶液移动通过所述膜的孔进入所述第二溶液，并将所述靶材固定在所述基板上。

公开(公告)号：US20110033919A1

公开(公告)日：2011-02-10

申请号：US12904557

申请日：2010-10-14

Applicant: Kak NAMKOONG ,  Su-hyeon KIM ,  Jin-tae KIM ,  Chin-sung PARK ,  Young-sun LEE

Inventor： Kak NAMKOONG ,  Su-hyeon KIM ,  Jin-tae KIM ,  Chin-sung PARK ,  Young-sun LEE

IPC: C12M1/40

CPC classification number: B81B3/0081 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00822 ,  B01J2219/00873 ,  B01L3/5027 ,  B01L7/5255 ,  B01L2200/14 ,  B01L2200/147 ,  B01L2300/1805 ,  B01L2300/1827 ,  B81B2201/051 ,  F28F21/02 ,  F28F2013/006

Abstract: A method of reducing a temperature difference between a high-temperature and a low-temperature substrate includes interposing a heat transfer facilitating layer which has a higher thermal conductivity than air and can hold particles between the substrates, and maintaining close contact between the high-temperature substrate, the heat transfer facilitating layer, and the low-temperature substrate, wherein formation of an air layer can be at least substantially prevented between the high-temperature substrate and the heat transfer facilitating layer, and between the low-temperature substrate and the heat transfer facilitating layer. A fluid reaction device includes a microfluidic reaction chip which accommodates a fluid, a heater, and a heat transfer facilitating layer which is interposed between the microfluidic reaction chip and the heater, the heat transfer facilitating layer has a higher thermal conductivity than air and can hold particles, wherein formation of an air layer can be prevented.

Abstract translation: 降低高温和低温基板之间的温度差的方法包括：介于热传导率高于空气的传热促进层，并且可以在基板之间保持颗粒，并且保持高温 基板，传热促进层和低温基板，其中至少可以在高温基板和传热促进层之间以及在低温基板和热量之间基本上防止空气层的形成 转移促进层。 流体反应装置包括容纳流体的微流体反应芯片，加热器和介于微流体反应芯片和加热器之间的传热促进层，传热促进层具有比空气更高的导热性并且可以保持 颗粒，其中可以防止空气层的形成。

公开(公告)号：US20120194811A1

公开(公告)日：2012-08-02

申请号：US13160854

申请日：2011-06-15

Applicant: June-young LEE ,  Hee-jeong JEONG ,  Seong-ho CHO ,  Su-hyeon KIM

Inventor： June-young LEE ,  Hee-jeong JEONG ,  Seong-ho CHO ,  Su-hyeon KIM

IPC: G01N21/01 ,  B32B38/10 ,  C23F1/00 ,  B82Y40/00 ,  B82Y15/00

CPC classification number: G01N1/10 ,  B01L3/502707 ,  B32B37/065 ,  B32B37/12 ,  B32B38/06 ,  B32B2535/00 ,  B82Y15/00 ,  G01N21/554 ,  G01N21/645 ,  Y10S977/953 ,  Y10S977/957 ,  Y10S977/958

Abstract: A nano particle tracking device includes a channel structure. The channel structure of the nano particle tracking device includes a pair of microchannels in which a specimen including nano particles is accommodated and which face each other, at least one nano channel which is between the pair of microchannels, which connects the pair of microchannels to each other and through which the nano particles in the specimen are moved, and a nano grating below the nano channel and crossing the nano channel perpendicularly.

Abstract translation: 纳米粒子跟踪装置包括通道结构。 纳米颗粒跟踪装置的通道结构包括一对微通道，其中包含纳米颗粒的样品被容纳并且彼此面对，在一对微通道之间的至少一个纳米通道，将一对微通道连接到每个微通道 样品中的纳米颗粒通过其移动，并且纳米通道下方的纳米光栅并且垂直穿过纳米通道。

公开(公告)号：US20120173157A1

公开(公告)日：2012-07-05

申请号：US13303861

申请日：2011-11-23

Applicant: Tae-jin AHN ,  Soyeon AHN ,  Sung-ho WON ,  Su-hyeon KIM ,  Taesung PARK ,  Sung-young LEE ,  Seung-yeoun LEE ,  Bora YEON ,  Young-ho PARK

Inventor： Tae-jin AHN ,  Soyeon AHN ,  Sung-ho WON ,  Su-hyeon KIM ,  Taesung PARK ,  Sung-young LEE ,  Seung-yeoun LEE ,  Bora YEON ,  Young-ho PARK

IPC: G06F19/20

CPC classification number: G06F19/22

Abstract: A method of recovering a nucleic acid sequence using a probe map includes: aligning a probe onto a target sequence based on a result in which the probe is hybridized to the target sequence; determining a representative value representing each aligned position of the probe; and recovering a base sequence of the target sequence by using a probe map to which the determined representative values and base sequence information of the probe are mapped.

Abstract translation: 使用探针图回收核酸序列的方法包括：基于探针与靶序列杂交的结果将探针对准靶序列; 确定表示探针的每个对准位置的代表值; 以及通过使用映射了所述探测器的确定的代表值和碱基序列信息的探针图来恢复所述目标序列的碱基序列。