公开(公告)号：US11957460B2

公开(公告)日：2024-04-16

申请号：US16777855

申请日：2020-01-30

Applicant: LifePlus Inc

Inventor： Kevin Hazen ,  Alan Abul-Haj ,  Roxanne Abul-Haj ,  Christopher Slawinski ,  Alodeep Sanyal ,  Benjamin Mbouombouo

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/145 ,  G01J3/10 ,  G01N33/49

CPC classification number: A61B5/1455 ,  A61B5/0022 ,  A61B5/0051 ,  A61B5/0053 ,  A61B5/14532 ,  A61B5/6824 ,  A61B5/6832 ,  G01J3/10 ,  G01N33/49 ,  A61B5/0004 ,  A61B5/7264 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/046 ,  G01J2003/102 ,  G01J2003/106

Abstract: The invention comprises a method and apparatus for sampling a common tissue volume and/or a common skin layer skin of a person as a part of noninvasively determining an analyte property with an analyzer including: a set of detectors at least partially embedded in a probe housing, the probe housing comprising a sample side surface, the detectors including a first and second range of detection zones of differing radial distances from a first illumination zone and second illumination zone, respectively coupled to separate sources, with surface paths between the sources and detectors overlapping a common skin area during use.

公开(公告)号：US12042279B2

公开(公告)日：2024-07-23

申请号：US16777829

申请日：2020-01-30

Applicant: LIFEPLUS Inc.

Inventor： Christopher Slawinski ,  Kevin Hazen ,  Roxanne Abul-Haj ,  Benjamin Mbouombouo ,  Alodeep Sanyal ,  Alan Abul-Haj

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/145 ,  G01J3/10 ,  G01N33/49

CPC classification number: A61B5/1455 ,  A61B5/0022 ,  A61B5/0051 ,  A61B5/0053 ,  A61B5/14532 ,  A61B5/6824 ,  A61B5/6832 ,  G01J3/10 ,  G01N33/49 ,  A61B5/0004 ,  A61B5/7264 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/046 ,  G01J2003/102 ,  G01J2003/106

Abstract: The invention comprises a method and apparatus for selecting optical pathways sampling a common tissue position, such as a lateral mean range in the dermis, of a person for analysis in a noninvasive analyte property determination system, comprising the steps of: probing skin with a range of illumination zone-to-detection zone distances with at least two wavelength ranges, which optionally overlap, and selecting, using a metric, illumination zone-to-detection zone distances having mean optical pathways probing the common tissue layer, such as without the mean optical pathways entering the subcutaneous fat layer of the person. Optionally, the skin tissue layers are modulated and/or treated via tissue displacement before and/or during data collection.

公开(公告)号：US11766200B2

公开(公告)日：2023-09-26

申请号：US16777842

申请日：2020-01-30

Applicant: LIFEPLUS Inc.

Inventor： Kevin Hazen ,  Benjamin Mbouombouo ,  Alodeep Sanyal ,  Alan Abul-Haj ,  Roxanne Abul-Haj ,  Christopher Slawinski

IPC: A61B5/1455 ,  A61B5/1477 ,  A61B5/00 ,  A61B5/145 ,  G01J3/10

CPC classification number: A61B5/1477 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/1455 ,  A61B5/14532 ,  A61B5/6824 ,  A61B5/6831 ,  A61B5/6832 ,  G01J2003/102

Abstract: The invention comprises a method and apparatus for sampling optical pathways having a common tissue depth, such as a maximum mean depth of penetration in the dermis, with a common sample position of a person for analysis in a noninvasive analyte property determination system, comprising the steps of: probing skin with a range of illumination zone-to-detection zone distances with at least two wavelength ranges and detecting, using a set of detectors, illumination zone-to-detection zone distances having mean optical pathways probing the common tissue layer, such as without the mean optical pathways entering the subcutaneous fat layer of the person. Optionally, the skin tissue layers are modulated and/or treated via tissue displacement before and/or during data collection. Optionally, given illumination zone-to-detection zone distances are dynamically selected based upon a measure of state of the skin of the person.