MOLECULAR BEACONS
    1.
    发明公开
    MOLECULAR BEACONS 审中-公开

    公开(公告)号:US20240018607A1

    公开(公告)日:2024-01-18

    申请号:US18252869

    申请日:2021-11-12

    CPC classification number: C12Q1/6897 C12Q1/44

    Abstract: Systems comprising a translation module, an amplification module comprising one or more sensing modalities, and a detection module configured to accept the amplifier output and methods of using the same are provided. The systems or methods can be capable of detecting trace amounts of nucleic acid molecules with high sensitivity and specificity in a device-free system with naked-eye readable output. The systems can comprise three layers incorporated into a lateral flow assay and/or a paper strip assay, in such systems, the first layer can comprise the translation module, the second layer can comprise the amplification module, and the third layer can comprise the detection module.

    SYSTEM FOR DETECTION OF A TARGET ANALYTE VIA SELF-TESTING, OBJECT SURFACES, AND THE ENVIRONMENT

    公开(公告)号:US20210333214A1

    公开(公告)日:2021-10-28

    申请号:US17219527

    申请日:2021-03-31

    Abstract: Systems and indicators for determining the presence or absence of specific environmental, exposure, or biological conditions are provided. Indicators include a plurality of sensors, each sensor independently having a biological or chemical sensing modality to detect one or more analytes of interest. Analytes of interest include nucleic acids (e.g., DNA, RNA, etc.), proteins, peptides, and other amino acid chains and may come from a subject or the microbiome of a subject. The signals from the plurality of sensors may be processed to provide a readily understandable readout concerning a health condition or predisposition of a subject, such as cancer and exposure to coronavirus. The signals from the plurality of sensors may be colorimetric (e.g. a color change in response to the presence or absence of an analyte), and a plurality of colorimetric signals may be combined to provide a readily understandable colorimetric output. Indicators may be wearable.

    SYSTEM FOR DETECTION OF A TARGET ANALYTE VIA SELF-TESTING, OBJECT SURFACES, AND THE ENVIRONMENT

    公开(公告)号:US20250146947A1

    公开(公告)日:2025-05-08

    申请号:US18740134

    申请日:2024-06-11

    Abstract: Systems and indicators for determining the presence or absence of specific environmental, exposure, or biological conditions are provided. Indicators include a plurality of sensors, each sensor independently having a biological or chemical sensing modality to detect one or more analytes of interest. Analytes of interest include nucleic acids (e.g., DNA, RNA, etc.), proteins, peptides, and other amino acid chains and may come from a subject or the microbiome of a subject. The signals from the plurality of sensors may be processed to provide a readily understandable readout concerning a health condition or predisposition of a subject, such as cancer and exposure to coronavirus. The signals from the plurality of sensors may be colorimetric (e.g. a color change in response to the presence or absence of an analyte), and a plurality of colorimetric signals may be combined to provide a readily understandable colorimetric output. Indicators may be wearable.

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