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公开(公告)号:US20240018607A1
公开(公告)日:2024-01-18
申请号:US18252869
申请日:2021-11-12
Applicant: LogicInk Corporation
Inventor: Carlos Edel OLGUIN ALVAREZ , Hendrik DIETZ , Steven WROBEL
IPC: C12Q1/6897 , C12Q1/44
CPC classification number: C12Q1/6897 , C12Q1/44
Abstract: Systems comprising a translation module, an amplification module comprising one or more sensing modalities, and a detection module configured to accept the amplifier output and methods of using the same are provided. The systems or methods can be capable of detecting trace amounts of nucleic acid molecules with high sensitivity and specificity in a device-free system with naked-eye readable output. The systems can comprise three layers incorporated into a lateral flow assay and/or a paper strip assay, in such systems, the first layer can comprise the translation module, the second layer can comprise the amplification module, and the third layer can comprise the detection module.
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2.
公开(公告)号:US20210333214A1
公开(公告)日:2021-10-28
申请号:US17219527
申请日:2021-03-31
Applicant: LogicInk Corporation
Inventor: Carlos Edel OLGUIN ALVAREZ , Steven WROBEL , Hendrik DIETZ
IPC: G01N21/78 , G01N27/414 , G01N21/27
Abstract: Systems and indicators for determining the presence or absence of specific environmental, exposure, or biological conditions are provided. Indicators include a plurality of sensors, each sensor independently having a biological or chemical sensing modality to detect one or more analytes of interest. Analytes of interest include nucleic acids (e.g., DNA, RNA, etc.), proteins, peptides, and other amino acid chains and may come from a subject or the microbiome of a subject. The signals from the plurality of sensors may be processed to provide a readily understandable readout concerning a health condition or predisposition of a subject, such as cancer and exposure to coronavirus. The signals from the plurality of sensors may be colorimetric (e.g. a color change in response to the presence or absence of an analyte), and a plurality of colorimetric signals may be combined to provide a readily understandable colorimetric output. Indicators may be wearable.
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3.
公开(公告)号:US20250146947A1
公开(公告)日:2025-05-08
申请号:US18740134
申请日:2024-06-11
Applicant: LogicInk Corporation
Inventor: Carlos Edel OLGUIN ALVAREZ , Steven WROBEL , Hendrik DIETZ
IPC: G01N21/78 , G01N21/27 , G01N21/77 , G01N27/414
Abstract: Systems and indicators for determining the presence or absence of specific environmental, exposure, or biological conditions are provided. Indicators include a plurality of sensors, each sensor independently having a biological or chemical sensing modality to detect one or more analytes of interest. Analytes of interest include nucleic acids (e.g., DNA, RNA, etc.), proteins, peptides, and other amino acid chains and may come from a subject or the microbiome of a subject. The signals from the plurality of sensors may be processed to provide a readily understandable readout concerning a health condition or predisposition of a subject, such as cancer and exposure to coronavirus. The signals from the plurality of sensors may be colorimetric (e.g. a color change in response to the presence or absence of an analyte), and a plurality of colorimetric signals may be combined to provide a readily understandable colorimetric output. Indicators may be wearable.
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公开(公告)号:US20200149960A1
公开(公告)日:2020-05-14
申请号:US16622793
申请日:2018-06-18
Applicant: LogicInk Corporation
Inventor: Peter FOLLER , Ian FRITZ , Carlos OLGUIN , Steven WROBEL , Claire Le MAITRE , E. Roon KANG , Skylar Jackson Eagle TIBBITS
Abstract: A wearable UV indicator, methods of making and using same. The indicator includes a polymeric film substrate having a first side and a second side, an adhesive disposed on the first side of the substrate, and a readily understood user interface disposed on the second side of the substrate, wherein the user interface comprises a qualitative indicator of instantaneous intensity of solar ultraviolet irradiation and a qualitative indicator of accumulated exposure to solar ultraviolet radiation.
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