公开(公告)号：US09068949B2

公开(公告)日：2015-06-30

申请号：US14171052

申请日：2014-02-03

Applicant: Purdue Research Foundation

Inventor： Ji-Xin Cheng ,  Mikhail N. Slipchenko ,  Robert A. Oglesbee

IPC: G01J3/28 ,  G01N21/65 ,  G01J3/02

CPC classification number: G01N21/65 ,  G01J3/02 ,  G01J3/2803

Abstract: A system for measuring an sample includes an illumination source providing electromagnetic radiation pulses at a selected temporal frequency. A microscope focuses the radiation to interact with the sample and produce resultant electromagnetic radiation. A disperser disperses wavelengths of the resultant radiation onto optical sensors, and respective resonant amplifiers amplify signals having the selected temporal frequency. Optical detection apparatus includes the optical sensors, resonant amplifiers, and disperser. The resonant amplifiers amplify portion(s) of their inputs having a selected temporal frequency and attenuate other portion(s). A method of analyzing constituents of a sample includes contemporaneously irradiating the sample with narrowband light and broadband light, the optical power of either modulated at a selected temporal frequency; dispersing wavelengths of resultant light across the optical detectors; and filtering respective signals from the optical detectors to provide spectrum data including signals corresponding to the selected temporal frequency.

Abstract translation: 用于测量样本的系统包括以选定的时间频率提供电磁辐射脉冲的照明源。 显微镜将放射线与样品相互作用并产生电磁辐射。 分散器将所得辐射的波长分散到光学传感器上，并且相应的谐振放大器放大具有所选择的时间频率的信号。 光学检测装置包括光学传感器，谐振放大器和分散器。 谐振放大器放大其输入的具有选定时间频率的部分，并衰减其它部分。 分析样品成分的方法包括同时以窄带光和宽带光照射样品，以选定的时间频率调制的光功率; 将所得光的波长分散在光学检测器上; 并且对来自光学检测器的各个信号进行滤波以提供包括对应于所选择的时间频率的信号的频谱数据。

公开(公告)号：US20140361150A1

公开(公告)日：2014-12-11

申请号：US14373197

申请日：2013-01-20

Applicant: Purdue Research Foundation

Inventor： Ji-Xin Cheng ,  Mikhail N. Slipchenko ,  Robert A. Oglesbee

IPC: G01N21/17 ,  G01B9/04

CPC classification number: G01N21/17 ,  G01B9/04 ,  G01J1/46 ,  G01J3/2803 ,  G01J3/44 ,  G01N21/65 ,  G01N2021/655 ,  G01N2201/12 ,  G02B21/002 ,  G02B21/16

Abstract: An optical imaging apparatus includes an optical signal source, an optical signal detector apparatus, and a resonant amplifier assembly. The optical signal source is configured (i) to generate an optical signal including a carrier signal and an imaging signal, and (ii) to guide the optical signal to a sample. The optical signal detector apparatus is configured (i) to detect a modified optical signal from the sample, and (ii) to generate an electrical image signal based on the modified optical signal. The electrical image signal includes a background component and a modulated image signal corresponding to an image of the sample. The resonant amplifier assembly is electrically coupled to the optical signal detector apparatus and is configured (i) to isolate the modulated image signal from the background component, (ii) to amplify the modulated image signal, and (iii) to rectify the modulated image signal.

Abstract translation: 光学成像装置包括光信号源，光信号检测装置和谐振放大器组件。 光信号源被配置为（i）产生包括载波信号和成像信号的光信号，以及（ii）将光信号引导到样本。 光信号检测器装置被配置为（i）检测来自样本的修改的光信号，以及（ii）基于修改的光信号产生电图像信号。 电图像信号包括对应于样本图像的背景分量和调制图像信号。 谐振放大器组件电耦合到光信号检测器装置，并且被配置为（i）将调制的图像信号与背景分量隔离，（ii）放大调制的图像信号，以及（iii）校正调制的图像信号 。

公开(公告)号：US09222878B2

公开(公告)日：2015-12-29

申请号：US14373197

申请日：2013-01-20

Applicant: Purdue Research Foundation

Inventor： Ji-Xin Cheng ,  Mikhail N. Slipchenko ,  Robert A. Oglesbee

IPC: G01N21/00 ,  G01N21/17 ,  G01N21/65 ,  G02B21/00 ,  G02B21/16 ,  G01J3/28 ,  G01J3/44 ,  G01B9/04 ,  G01J1/46

CPC classification number: G01N21/17 ,  G01B9/04 ,  G01J1/46 ,  G01J3/2803 ,  G01J3/44 ,  G01N21/65 ,  G01N2021/655 ,  G01N2201/12 ,  G02B21/002 ,  G02B21/16

Abstract: An optical imaging apparatus includes an optical signal source, an optical signal detector apparatus, and a resonant amplifier assembly. The optical signal source is configured (i) to generate an optical signal including a carrier signal and an imaging signal, and (ii) to guide the optical signal to a sample. The optical signal detector apparatus is configured (i) to detect a modified optical signal from the sample, and (ii) to generate an electrical image signal based on the modified optical signal. The electrical image signal includes a background component and a modulated image signal corresponding to an image of the sample. The resonant amplifier assembly is electrically coupled to the optical signal detector apparatus and is configured (i) to isolate the modulated image signal from the background component, (ii) to amplify the modulated image signal, and (iii) to rectify the modulated image signal.

Abstract translation: 光学成像装置包括光信号源，光信号检测装置和谐振放大器组件。 光信号源被配置为（i）产生包括载波信号和成像信号的光信号，以及（ii）将光信号引导到样本。 光信号检测器装置被配置为（i）检测来自样本的修改的光信号，以及（ii）基于修改的光信号产生电图像信号。 电图像信号包括对应于样本图像的背景分量和调制图像信号。 谐振放大器组件电耦合到光信号检测器装置，并且被配置为（i）将调制的图像信号与背景分量隔离，（ii）放大调制的图像信号，以及（iii）校正调制的图像信号 。