公开(公告)号：US20220268745A1

公开(公告)日：2022-08-25

申请号：US17737163

申请日：2022-05-05

Applicant: Puridify Ltd.

Inventor： Michael Williams ,  Iwan Roberts ,  Oliver Hardick ,  Matthew Townsend ,  Christopher Morris ,  Shameer Subratty

IPC: G01N30/38 ,  G01N30/60 ,  G01N30/84

Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.

公开(公告)号：US20240210365A1

公开(公告)日：2024-06-27

申请号：US18408693

申请日：2024-01-10

Applicant: Puridify Ltd.

Inventor： Michael Williams ,  Iwan Roberts ,  Oliver Hardick ,  Matthew Townsend ,  Christopher Morris ,  Shameer Subratty

IPC: G01N30/38 ,  G01N30/60

CPC classification number: G01N30/38 ,  G01N30/6017 ,  G01N2030/386

Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.

公开(公告)号：US11913918B2

公开(公告)日：2024-02-27

申请号：US17737163

申请日：2022-05-05

Applicant: Puridify Ltd.

Inventor： Michael Williams ,  Iwan Roberts ,  Oliver Hardick ,  Matthew Townsend ,  Christopher Morris ,  Shameer Subratty

IPC: G01N30/38 ,  G01N30/60

CPC classification number: G01N30/38 ,  G01N30/6017 ,  G01N2030/386 ,  G01N30/6017 ,  G01N2030/386

Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.

公开(公告)号：US11353433B2

公开(公告)日：2022-06-07

申请号：US16327985

申请日：2017-08-25

Applicant: Puridify Ltd.

Inventor： Michael Williams ,  Iwan Roberts ,  Oliver Hardick ,  Matthew Townsend ,  Christopher Morris ,  Shameer Subratty

IPC: G01N30/38 ,  G01N30/60 ,  G01N30/84

Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.

公开(公告)号：US20190234914A1

公开(公告)日：2019-08-01

申请号：US16327985

申请日：2017-08-25

Applicant: Puridify Ltd.

Inventor： Michael Williams ,  Iwan Roberts ,  Oliver Hardick ,  Matthew Townsend ,  Christopher Morris ,  Shameer Subratty

IPC: G01N30/38 ,  G01N30/60 ,  G01N30/84

CPC classification number: G01N30/38 ,  G01N30/6017 ,  G01N30/84 ,  G01N2030/386

Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.