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公开(公告)号：US20220268745A1
公开(公告)日：2022-08-25
申请号：US17737163
申请日：2022-05-05
Applicant: Puridify Ltd.
Inventor： Michael Williams , Iwan Roberts , Oliver Hardick , Matthew Townsend , Christopher Morris , Shameer Subratty
Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.
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公开(公告)号：US20240210365A1
公开(公告)日：2024-06-27
申请号：US18408693
申请日：2024-01-10
Applicant: Puridify Ltd.
Inventor： Michael Williams , Iwan Roberts , Oliver Hardick , Matthew Townsend , Christopher Morris , Shameer Subratty
CPC classification number: G01N30/38 , G01N30/6017 , G01N2030/386
Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.
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Patent Agency Ranking
公开(公告)号：US11913918B2
公开(公告)日：2024-02-27
申请号：US17737163
申请日：2022-05-05
Applicant: Puridify Ltd.
Inventor： Michael Williams , Iwan Roberts , Oliver Hardick , Matthew Townsend , Christopher Morris , Shameer Subratty
CPC classification number: G01N30/38 , G01N30/6017 , G01N2030/386 , G01N30/6017 , G01N2030/386
Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.
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公开(公告)号：US20220297031A1
公开(公告)日：2022-09-22
申请号：US17608940
申请日：2020-05-12
Applicant: Puridify Ltd
Inventor： Shameer Subratty , Klaus Gebauer , Anindya Sengupta , Anji Venna , Hannes Hjorter , Adam Pinnock , Ralph Stankowski
Abstract: A chromatography device (1; 101) comprising: —at least one chromatography material unit (3), wherein said chromatography material unit comprises a convection-based chromatography material; —at least one fluid distribution system (7) which is configured to distribute fluid into and out from the at least one chromatography material unit (3); —an inlet (15); —at least one inlet fluid channel (17a, 17b) connecting the inlet (15) with each chromatography material unit (3) via the fluid distribution system (7); —an outlet (19); and —at least one outlet fluid channel (21) connecting the outlet (19) with each chromatography material unit (3) via the fluid distribution system (7), wherein at least some parts of said chromatography device (1; 101) are overmolded and sealed together by plastic or elastomer leaving at least the inlet (15) and the outlet (19) open.
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公开(公告)号：US11353433B2
公开(公告)日：2022-06-07
申请号：US16327985
申请日：2017-08-25
Applicant: Puridify Ltd.
Inventor： Michael Williams , Iwan Roberts , Oliver Hardick , Matthew Townsend , Christopher Morris , Shameer Subratty
Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.
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公开(公告)号：US20190234914A1
公开(公告)日：2019-08-01
申请号：US16327985
申请日：2017-08-25
Applicant: Puridify Ltd.
Inventor： Michael Williams , Iwan Roberts , Oliver Hardick , Matthew Townsend , Christopher Morris , Shameer Subratty
CPC classification number: G01N30/38 , G01N30/6017 , G01N30/84 , G01N2030/386
Abstract: A chromatography system for at least one of tangential flow chromatography and lateral flow chromatography comprising: an inlet; a functionalised adsorbent chromatography medium downstream of the inlet; an outlet downstream of the adsorbent chromatography medium; and a flow guide downstream of the inlet and upstream of the adsorbent chromatography medium and configured to distribute a flow of a liquid from the inlet across a width of the adsorbent chromatography medium; wherein the flow guide comprises a pattern of channels providing flow paths from the inlet to different parts of the adsorbent chromatography medium along the width of the adsorbent chromatography medium, wherein the pattern of channels is provided so as to reduce a difference in arrival time and/or flow velocity of liquid reaching the adsorbent chromatography medium across the width of the adsorbent chromatography medium.
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