公开(公告)号：US20240003741A1

公开(公告)日：2024-01-04

申请号：US18033247

申请日：2021-10-22

Applicant: RSP SYSTEMS A/S

Inventor： Martin SCHJOLDAGER NIELSEN ,  Joshua John GIBSON ,  Thomas James WATSON

IPC: G01J3/10 ,  G01J3/44 ,  G01N21/65 ,  A61B5/1455

CPC classification number: G01J3/10 ,  G01J3/44 ,  G01N21/65 ,  A61B5/1455 ,  G01N2201/06113 ,  A61B2562/0238 ,  G01J2003/102 ,  G01J2003/4424

Abstract: The present invention relates to an apparatus and method for non-invasive in vivo measurement, by Raman spectroscopy, of glucose present in interstitial fluid in the skin of a subject. The apparatus comprises at least one detector; a plurality of vertical-cavity surface-emitting lasers spatially distributed around the at least one detector, for irradiating the skin of a subject; wherein the at least one detector is configured to receive Raman scattered radiation transmitted from the sample in response to the received radiation from the vertical-cavity surface-emitting lasers.