Determining a distribution of spots of varying sizes for ion beam therapy based on user configuration

    公开(公告)号:US11602644B2

    公开(公告)日:2023-03-14

    申请号:US16625895

    申请日:2018-06-26

    Abstract: It is provided a method for determining a distribution of spots for use with ion beam therapy for providing the spots in a target volume, wherein each spot represents a collection of ions of a specific energy level and of a specific size at a specific lateral location. The method is performed in a treatment planning system and comprises the steps of: dividing the target volume in a plurality of target sections based on a user configuration comprising at least one spot size strategy defining a maximum spot size at the location of a Bragg peak; assigning a spot size strategy to each one of the target sections based on the location of the respective target section; and determining, within each target section, spots in accordance with its spot size strategy.

    Determining a distribution of spots of varying sizes for ion beam therapy using optimization

    公开(公告)号:US11020616B2

    公开(公告)日:2021-06-01

    申请号:US16625871

    申请日:2018-06-26

    Abstract: According to a first aspect, it is presented a method for determining a treatment plan comprising a distribution of spots for use with ion beam therapy for providing the spots in a target volume. The method comprises the steps of: selecting energy layers to be used in the treatment plan; determining a number of spot sizes to use; generating, for each energy layer, one copy of the energy layer for each spot size to use and populating each copy with spots of the spot size for that copy; optimizing spots of all copies of all energy layers, by repeatedly varying a weight of at least a subset of the spots and calculating an effect on a performance measurement, wherein the performance measurement is calculated by combining a plurality of evaluation criteria, comprising a first criterion related to total treatment time and a second criterion related to a desired dose distribution.

    Assigning ripple filter settings to a plurality of sub-beams

    公开(公告)号:US11446517B2

    公开(公告)日:2022-09-20

    申请号:US16625988

    申请日:2018-06-28

    Abstract: It is provided a method for determining ripple filter settings for an ion therapy beam being capable of providing ions of different energy levels to a target volume. The method is performed in a treatment planning system and comprises the steps of: determining at least one beam direction to use to cover a target volume; and assigning a ripple filter setting to each one of a plurality of sub-beams of each one of the at least one beam direction such that each sub-beam is assigned a different ripple filter setting, wherein each ripple filter setting results in a different effect on a Bragg-peak width in a direction along the ion therapy beam, and each energy level is assigned to one of the plurality of sub-beams. The step of assigning a ripple filter setting comprises optimising based on different filter settings for different sub-beams for each beam direction.

    Method of ion PBS treatment optimization, computer program product and computer system for performing the method

    公开(公告)号:US12023517B2

    公开(公告)日:2024-07-02

    申请号:US18552670

    申请日:2022-02-17

    CPC classification number: A61N5/1031 A61N5/1043 A61N2005/1087

    Abstract: A computer-based method of providing a set of selected spots for use in ion radiotherapy optimization is proposed, the method comprising the steps of defining a number of positions in the volume, each position corresponding to a possible Bragg peak location, the positions being defined to provide coverage of the volume, for each position, for at least one beam direction, performing a ray trace to determine characteristics of a potential spot in the beam that will place its Bragg peak in the position and for each position, selecting zero, one or more of the potential spots, based on the characteristics, and including the one or more selected spots in the set of selected spots. The set of selected spots may be used in treatment planning. The invention also relates to computer program products and a computer system for performing the methods.

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