公开(公告)号：US20210299635A1

公开(公告)日：2021-09-30

申请号：US16328332

申请日：2017-08-10

Applicant: SHOWA DENKO K.K.

Inventor： Hideyuki KONDO

IPC: B01J20/285 ,  B01J20/28 ,  B01D15/30 ,  B01D15/38 ,  B01D15/32 ,  B01D15/36 ,  B01J20/281

Abstract: A liquid chromatography packing material which includes a polymer packing material into which 1.50 mmol or more of carboxyl groups are introduced per 1 g of the packing material, and an index indicating pH of the surface of the polymer packing material as determined by hydrophilic interaction chromatography (HILIC) is 1.30 or more and the index indicating hydrophilicity of the surface of the polymer packing material as determined by a hydrophilic interaction chromatography (HILIC) is from 1.00 to 1.30.

公开(公告)号：US20170007981A1

公开(公告)日：2017-01-12

申请号：US15121806

申请日：2015-02-23

Applicant: SHOWA DENKO K.K.

Inventor： Naoya NAKAJIMA ,  Yoshiji OKADA ,  Hideyuki KONDO

IPC: B01J20/24 ,  B01J20/281 ,  G01N30/60 ,  B01D15/30 ,  B01J20/291

CPC classification number: B01J20/24 ,  B01D15/305 ,  B01J20/265 ,  B01J20/286 ,  B01J20/289 ,  B01J20/291 ,  B01J20/321 ,  B01J20/3219 ,  B01J20/3248 ,  B01J20/3251 ,  B01J20/34 ,  G01N30/48 ,  G01N30/482 ,  G01N30/60 ,  G01N30/88 ,  G01N33/02 ,  G01N2030/027

Abstract: A packing material for liquid chromatography, which is excellent in durability, and a column for liquid chromatography, which is filled with the packing material, are provided. The packing material for liquid chromatography is characterized by comprising a hydrophilic resin containing a polyvinyl alcohol resin, to said hydrophilic resin an amino group represented by the formula (1) having been bonded through a spacer. In the formula (1), R1 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R2 represents an alkyl group having 1 to 6 carbon atoms and having one or more hydroxyl groups, and  represents a bonding position to the spacer.

Abstract translation: 提供一种填充有填充材料的用于液相色谱的耐久性优异的液相色谱柱和液相色谱柱。 用于液相色谱的包装材料的特征在于包含含有聚乙烯醇树脂的亲水性树脂，所述亲水性树脂由通过间隔物结合的式（1）表示的氨基。 式（1）中，R 1表示氢原子或碳原子数1〜4的烷基，R 2表示碳原子数1〜6的烷基，具有一个以上羟基，并且表示与 间隔

公开(公告)号：US20180238842A1

公开(公告)日：2018-08-23

申请号：US15752322

申请日：2016-08-23

Applicant: SHOWA DENKO K.K.

Inventor： Junya KATO ,  Hideyuki KONDO ,  Naoko MARUOKA ,  Anne RIESS

IPC: G01N30/60 ,  G01N30/56 ,  B01D15/22 ,  G01N30/88 ,  B01J20/285 ,  B01J20/26

CPC classification number: G01N30/6052 ,  B01D15/22 ,  B01J20/265 ,  B01J20/285 ,  G01N30/56 ,  G01N30/603 ,  G01N30/88 ,  G01N2030/524

Abstract: A liquid chromatographic column includes: a cylindrical column body; an inflow-side filter that is disposed at an eluent inflow-side end of the column body; an outflow-side filter that is disposed at an eluent outflow-side end of the column body; and a filler that is filled between the inflow-side filter and the outflow-side filter, in which the inflow-side filter has a two-layer structure consisting of a first resin filter member and a second resin filter member which are disposed in this order from a side of the filler, and the first resin filter member has an indentation elastic modulus lower than that of the second resin filter member.

公开(公告)号：US20190204278A1

公开(公告)日：2019-07-04

申请号：US16302253

申请日：2017-05-25

Applicant: SHOWA DENKO K.K.

Inventor： Hideyuki KONDO ,  Junya KATO ,  Naoko MARUOKA

IPC: B01J20/281 ,  G01N30/56 ,  G01N30/32

CPC classification number: G01N30/482 ,  G01N30/26 ,  G01N30/32 ,  G01N30/56 ,  G01N30/88 ,  G01N2030/027 ,  G01N2030/324 ,  G01N2030/484 ,  G01N2030/562

Abstract: A liquid chromatography packing material employing crosslinked polymer particles, wherein the volume average particle size of the crosslinked polymer particles is at least 2 μm but not more than 10 μm, the amount of fine particles having a particle size of 1 μm or less among the crosslinked polymer particles is less than 1% by volume, and the identity coefficient in the particle size distribution is not more than 1.15.

公开(公告)号：US20170108474A1

公开(公告)日：2017-04-20

申请号：US15128310

申请日：2015-03-19

Applicant: SHOWA DENKO K.K.

Inventor： Hideyuki KONDO ,  Junji SASUGA ,  Takayuki SHUKUYA

IPC: G01N30/52 ,  B01D15/36 ,  G01N30/96 ,  G01N30/72 ,  G01N30/60

CPC classification number: G01N30/52 ,  B01D15/305 ,  B01D15/363 ,  B01D15/3847 ,  G01N27/62 ,  G01N30/02 ,  G01N30/26 ,  G01N30/56 ,  G01N30/6052 ,  G01N30/72 ,  G01N30/7233 ,  G01N30/88 ,  G01N30/96

Abstract: A mass spectrometry method by a liquid chromatograph-mass spectrometer that can detect an organic acid with high sensitivity by retaining, separating and eluting the organic acid without adding any nonvolatile substance to a mobile phase and without receiving any restriction of a ratio of a water-soluble organic solvent, and an analytical column are provided. The mass spectrometry method is a mass spectrometry method for an organic acid by a liquid chromatograph-mass spectrometer, wherein a column packed with a hydrophilic polymer having an anion-exchange group is used, and as a mobile phase, a water-soluble organic solvent-water mixed solution is used. The analytical column is a column for liquid chromatography for an organic acid, in which a polyether ether ketone (PEEK) resin housing for liquid chromatography is packed with a hydrophilic polymer having an anion-exchange group.

公开(公告)号：US20190184372A1

公开(公告)日：2019-06-20

申请号：US16327437

申请日：2017-08-10

Applicant: SHOWA DENKO K.K.

Inventor： Junya KATO ,  Hideyuki KONDO ,  Ryuji TAKAHASHI

IPC: B01J20/26 ,  B01J20/285 ,  B01J20/28 ,  G01N30/88 ,  B01J20/281

CPC classification number: B01J20/267 ,  B01D15/00 ,  B01D15/38 ,  B01D15/42 ,  B01J20/26 ,  B01J20/28 ,  B01J20/28004 ,  B01J20/28083 ,  B01J20/281 ,  B01J20/285 ,  B01J2220/54 ,  B01J2220/58 ,  B01J2220/86 ,  G01N30/482 ,  G01N30/88 ,  G01N2030/8836

Abstract: Provided is a packing material for HILIC columns for more accurately and more easily performing oligosaccharide analysis by liquid chromatography; an HILIC column which is filled with the packing material for HILIC columns; and a method for analyzing an oligosaccharide with use of this packing material for HILIC columns A packing material for HILIC columns according to the present invention is composed of particles, each of which is obtained by reacting glycidol to a hydroxyl group of a porous cross-linked polymer base material having the hydroxyl group, and which have a hydrophilicity index of 2.30 or more and a surface-pH index of from 0.95 to 1.05.

公开(公告)号：US20190015813A1

公开(公告)日：2019-01-17

申请号：US16135305

申请日：2018-09-19

Applicant: SHOWA DENKO K.K.

Inventor： Naoya NAKAJIMA ,  Yoshiji OKADA ,  Hideyuki KONDO

IPC: B01J20/24 ,  B01J20/281 ,  B01J20/26 ,  G01N30/88 ,  G01N30/60 ,  B01D15/30 ,  B01J20/34 ,  B01J20/291 ,  B01J20/289 ,  B01J20/286 ,  G01N33/02 ,  G01N30/02

Abstract: A packing material for liquid chromatography, which is excellent in durability, and a column for liquid chromatography, which is filled with the packing material, are provided. The packing material for liquid chromatography is characterized by comprising a hydrophilic resin containing a polyvinyl alcohol resin, to said hydrophilic resin an amino group represented by the formula (1) having been bonded through a spacer. In the formula (1), R1 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R2 represents an alkyl group having 1 to 6 carbon atoms and having one or more hydroxyl groups, and ※ represents a bonding position to the spacer.