Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis

    公开(公告)号:US11141065B2

    公开(公告)日:2021-10-12

    申请号:US16355039

    申请日:2019-03-15

    Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

    Eyelid illumination systems and method for imaging meibomian glands for meibomian gland analysis

    公开(公告)号:US10278587B2

    公开(公告)日:2019-05-07

    申请号:US14269646

    申请日:2014-05-05

    Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

    EYELID ILLUMINATION SYSTEMS AND METHODS FOR IMAGING MEIBOMIAN GLANDS FOR MEIBOMIAN GLAND ANALYSIS
    6.
    发明申请
    EYELID ILLUMINATION SYSTEMS AND METHODS FOR IMAGING MEIBOMIAN GLANDS FOR MEIBOMIAN GLAND ANALYSIS 审中-公开
    用于成像墨西哥甘蓝分析的眼睛照射系统和方法

    公开(公告)号:US20140330129A1

    公开(公告)日:2014-11-06

    申请号:US14269646

    申请日:2014-05-05

    CPC classification number: A61B5/0082 A61B5/0077 A61B5/6821

    Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

    Abstract translation: 公开了眼睑照射系统和用于睑板腺分析成像睑板腺的方法。 在一个实施例中,患者的眼睑用红外(IR)光IR反照射。 捕获患者眼睑的透射照明图像,显示黑色轮廓区域中的睑板腺,而非腺体材料显示在浅色区域。 这提供了像X射线的睑板腺的高对比度图像。 可以分析睑板腺的盖反照明图像,以确定诊断患者眼睑中的睑板腺。 眼睑可以由构造成抓住并翻转眼睑的盖翻转装置反照,以对眼睑的内表面进行成像。 此外,还可以捕获睑板腺的IR表面记录图像并与睑板腺的反照明图像组合,以提供睑板腺的较高对比度图像。

    Methods and apparatuses for determining contact lens intolerance in contact lens wearer patients based on dry eye tear film characteristic analysis and dry eye symptoms

    公开(公告)号:US10716465B2

    公开(公告)日:2020-07-21

    申请号:US15892549

    申请日:2018-02-09

    Abstract: Methods and apparatuses for determining contact lens intolerance in contact lens wearer patients based on tear film characteristics analysis and dry eye symptoms are disclosed. In embodiments herein, imaging of the ocular tear film is performed during contact lens wear. An analysis of the image of the ocular tear film is performed to determine one or more tear film characteristics of the ocular tear film. The tear film characteristics can be used to determine the effect or possible effect of contact lens wear on the ocular tear film, and thus be used to determine contact lens intolerance of the patient. The tear film characteristics used to analyze contact lens intolerance based on images of the ocular tear film involving contact lens wear may include dry eye symptoms, including but not limited to tear film (e.g., lipid and/or aqueous) thickness, tear film viscosity, and tear film movement rate in the eye.

    METHODS AND APPARATUSES FOR DETERMINING CONTACT LENS INTOLERANCE IN CONTACT LENS WEARER PATIENTS BASED ON DRY EYE TEAR FILM CHARACTERISTIC ANALYSIS AND DRY EYE SYMPTOMS
    9.
    发明申请
    METHODS AND APPARATUSES FOR DETERMINING CONTACT LENS INTOLERANCE IN CONTACT LENS WEARER PATIENTS BASED ON DRY EYE TEAR FILM CHARACTERISTIC ANALYSIS AND DRY EYE SYMPTOMS 有权
    用于确定接触镜片的联系人眼镜不透明度的方法和装置基于干眼眼膜的特征分析和干眼症状

    公开(公告)号:US20140240671A1

    公开(公告)日:2014-08-28

    申请号:US14268647

    申请日:2014-05-02

    CPC classification number: A61B3/0025 A61B3/101 G06T7/0012 G06T2207/30041

    Abstract: Methods and apparatuses for determining contact lens intolerance in contact lens wearer patients based on tear film characteristics analysis and dry eye symptoms are disclosed. In embodiments herein, imaging of the ocular tear film is performed during contact lens wear. An analysis of the image of the ocular tear film is performed to determine one or more tear film characteristics of the ocular tear film. The tear film characteristics can be used to determine the effect or possible effect of contact lens wear on the ocular tear film, and thus be used to determine contact lens intolerance of the patient. The tear film characteristics used to analyze contact lens intolerance based on images of the ocular tear film involving contact lens wear may include dry eye symptoms, including but not limited to tear film (e.g., lipid and/or aqueous) thickness, tear film viscosity, and tear film movement rate in the eye.

    Abstract translation: 公开了基于泪膜特性分析和干眼症状来确定隐形眼镜佩戴者患者中隐形眼镜不耐受性的方法和装置。 在本文的实施例中,在隐形眼镜佩戴期间进行眼泪膜的成像。 执行眼泪膜的图像分析,以确定眼泪膜的一个或多个泪膜特性。 可以使用泪膜特性来确定隐形眼镜磨损对眼泪膜的影响或可能的影响,因此用于确定患者的隐形眼镜不耐受性。 基于涉及隐形眼镜磨损的眼泪膜的图像,用于分析隐形眼镜不耐受的泪膜特征可包括干眼症状,包括但不限于泪膜(例如,脂质和/或水性)厚度,泪膜粘度, 和眼膜中的泪膜移动速率。

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