Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis

    公开(公告)号:US11141065B2

    公开(公告)日:2021-10-12

    申请号:US16355039

    申请日:2019-03-15

    Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

    EYELID ILLUMINATION SYSTEMS AND METHODS FOR IMAGING MEIBOMIAN GLANDS FOR MEIBOMIAN GLAND ANALYSIS

    公开(公告)号:US20220022741A1

    公开(公告)日:2022-01-27

    申请号:US17498102

    申请日:2021-10-11

    Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured, showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray-like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

    EYELID ILLUMINATION SYSTEMS AND METHODS FOR IMAGING MEIBOMIAN GLANDS FOR MEIBOMIAN GLAND ANALYSIS

    公开(公告)号:US20190209014A1

    公开(公告)日:2019-07-11

    申请号:US16355039

    申请日:2019-03-15

    CPC classification number: A61B5/0082 A61B5/0077 A61B5/6821

    Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

    Eyelid illumination systems and method for imaging meibomian glands for meibomian gland analysis

    公开(公告)号:US10278587B2

    公开(公告)日:2019-05-07

    申请号:US14269646

    申请日:2014-05-05

    Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

    EYELID ILLUMINATION SYSTEMS AND METHODS FOR IMAGING MEIBOMIAN GLANDS FOR MEIBOMIAN GLAND ANALYSIS
    9.
    发明申请
    EYELID ILLUMINATION SYSTEMS AND METHODS FOR IMAGING MEIBOMIAN GLANDS FOR MEIBOMIAN GLAND ANALYSIS 审中-公开
    用于成像墨西哥甘蓝分析的眼睛照射系统和方法

    公开(公告)号:US20140330129A1

    公开(公告)日:2014-11-06

    申请号:US14269646

    申请日:2014-05-05

    CPC classification number: A61B5/0082 A61B5/0077 A61B5/6821

    Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

    Abstract translation: 公开了眼睑照射系统和用于睑板腺分析成像睑板腺的方法。 在一个实施例中,患者的眼睑用红外(IR)光IR反照射。 捕获患者眼睑的透射照明图像,显示黑色轮廓区域中的睑板腺,而非腺体材料显示在浅色区域。 这提供了像X射线的睑板腺的高对比度图像。 可以分析睑板腺的盖反照明图像,以确定诊断患者眼睑中的睑板腺。 眼睑可以由构造成抓住并翻转眼睑的盖翻转装置反照,以对眼睑的内表面进行成像。 此外,还可以捕获睑板腺的IR表面记录图像并与睑板腺的反照明图像组合,以提供睑板腺的较高对比度图像。

    OPTICAL PHANTOMS FOR USE WITH OCULAR SURFACE INTERFEROMETRY (OSI) DEVICES AND SYSTEMS CONFIGURED TO MEASURE TEAR FILM LAYER THICKNESS(ES), AND RELATED USE FOR CALIBRATION
    10.
    发明申请
    OPTICAL PHANTOMS FOR USE WITH OCULAR SURFACE INTERFEROMETRY (OSI) DEVICES AND SYSTEMS CONFIGURED TO MEASURE TEAR FILM LAYER THICKNESS(ES), AND RELATED USE FOR CALIBRATION 审中-公开
    用于表面干涉测量(OSI)的光学仪器配置用于测量薄膜厚度(ES)的仪器和系统,以及用于校准的相关用途

    公开(公告)号:US20130293842A1

    公开(公告)日:2013-11-07

    申请号:US13886383

    申请日:2013-05-03

    Abstract: Embodiments of the detailed description include optical phantoms for use with ocular surface interferometery (OSI) devices and systems configured to measure tear film layer thickness(es), and related use for calibration. The ocular surface interferometry (OSI) devices, systems, and methods can be used for imaging an ocular tear film and/or measuring a tear film layer thickness (TFLT) in a patient's ocular tear film. The OSI devices, systems, and methods can be used to measure the thickness of the lipid layer component (LLT) and/or the aqueous layer component (ALT) of the ocular tear film. “TFLT” as used herein includes LLT, ALT, or both LLT and ALT. “Measuring TFLT” as used herein includes measuring LLT, ALT, or both LLT and ALT. Imaging the ocular tear film and measuring TFLT can be used in the diagnosis of a patient's tear film, including but not limited to lipid layer and aqueous layer deficiencies.

    Abstract translation: 详细描述的实施例包括用于眼表面干涉仪(OSI)装置的光学幻影和被配置为测量泪膜层厚度的系统以及用于校准的相关用途。 可以使用眼表干涉测量(OSI)装置,系统和方法来成像眼泪膜和/或测量患者眼泪膜中的泪膜层厚度(TFLT)。 OSI装置,系统和方法可用于测量眼泪膜的脂质层组分(LLT)和/或水层组分(ALT)的厚度。 本文所用的“TFLT”包括LLT,ALT或LLT和ALT两者。 本文所用的“测量TFLT”包括测量LLT,ALT或LLT和ALT两者。 成像眼泪膜并测量TFLT可用于诊断患者的泪膜,包括但不限于脂质层和水层缺陷。

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