公开(公告)号：US11141065B2

公开(公告)日：2021-10-12

申请号：US16355039

申请日：2019-03-15

Applicant: TearScience, Inc.

Inventor： Stephen M. Grenon ,  Donald R. Korb ,  Joshua Grenon ,  Scott Liddle ,  Steve Bacich ,  John M. Jans

IPC: A61B5/00

Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

公开(公告)号：US11844586B2

公开(公告)日：2023-12-19

申请号：US17498102

申请日：2021-10-11

Applicant: TearScience, Inc.

Inventor： Stephen M. Grenon ,  Donald R. Korb ,  Joshua Grenon ,  Scott Liddle ,  Steve Bacich ,  John M. Jans

IPC: A61B5/00 ,  A61B3/00 ,  A61B3/10

CPC classification number: A61B5/0082 ,  A61B3/0008 ,  A61B3/101 ,  A61B5/0077 ,  A61B5/6821

Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured, showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray-like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

公开(公告)号：US10278587B2

公开(公告)日：2019-05-07

申请号：US14269646

申请日：2014-05-05

Applicant: TEARSCIENCE, INC.

Inventor： Stephen M. Grenon ,  Donald R. Korb ,  Joshua Grenon ,  Scott Liddle ,  Steve Bacich ,  John M. Jans

IPC: A61B5/00

Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

公开(公告)号：US20220022741A1

公开(公告)日：2022-01-27

申请号：US17498102

申请日：2021-10-11

Applicant: TearScience, Inc.

Inventor： Stephen M. Grenon ,  Donald R. Korb ,  Joshua Grenon ,  Scott Liddle ,  Steve Bacich ,  John M. Jans

IPC: A61B3/00 ,  A61B3/10

Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured, showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray-like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.

公开(公告)号：US20190209014A1

公开(公告)日：2019-07-11

申请号：US16355039

申请日：2019-03-15

Applicant: TearScience, Inc.

Inventor： Stephen M. Grenon ,  Donald R. Korb ,  Joshua Grenon ,  Scott Liddle ,  Steve Bacich ,  John M. Jans

IPC: A61B5/00

CPC classification number: A61B5/0082 ,  A61B5/0077 ,  A61B5/6821

Abstract: Eyelid illumination systems and methods for imaging meibomian glands for meibomian gland analysis are disclosed. In one embodiment, a patient's eyelid is IR trans-illuminated with an infrared (IR) light. A trans-illumination image of the patient's eyelid is captured showing meibomian glands in dark outlined areas, whereas non-gland material is shown in light areas. This provides a high contrast image of the meibomian glands that is X-ray like. The lid trans-illumination image of the meibomian glands can be analyzed to determine to diagnose the meibomian glands in the patient's eyelid. The eyelid may be trans-illuminated by a lid-flipping device configured to grasp and flip the eyelid for imaging the interior surface of the eyelid. Also, an IR surface meibography image of the meibomian glands may also be captured and combined with the trans-illumination image of the meibomian glands to provide a higher contrast image of the meibomian glands.