公开(公告)号：US20200375476A1

公开(公告)日：2020-12-03

申请号：US16970670

申请日：2019-02-18

Applicant: THE GENERAL HOSPITAL CORPORATION

Inventor： Maria Angela Franceschini ,  Stefan Carp ,  Davide Tamborini ,  David Boas ,  Bruce Rosen ,  Megan Blackwell ,  Oleg Shatrovoy

IPC: A61B5/026 ,  G01J1/44

Abstract: An apparatus, including: a probe to interface with a surface of a tissue; a light source optically coupled to the probe, the light source directing light of at least 1000 nm into the tissue; a detector optically coupled to the probe, the detector to detect light based on scattering of light from the light source in the tissue, and the detector having a light sensitivity in a range of at least 1000 nm; a processor coupled to the detector, the processor to: receive a signal from the detector corresponding to the detected light from the light source, and determine a blood flow measurement from the region of interest using diffuse correlation spectroscopy based on the signal.

公开(公告)号：US11872022B2

公开(公告)日：2024-01-16

申请号：US16970670

申请日：2019-02-18

Applicant: THE GENERAL HOSPITAL CORPORATION

Inventor： Maria Angela Franceschini ,  Stefan Carp ,  Davide Tamborini ,  David Boas ,  Bruce Rosen ,  Megan Blackwell ,  Oleg Shatrovoy

IPC: A61B5/026 ,  G01J1/44 ,  H01L31/107 ,  H01L31/109

CPC classification number: A61B5/0261 ,  G01J1/44 ,  A61B2562/0233 ,  G01J2001/448 ,  G01J2001/4453 ,  G01J2001/4466 ,  H01L31/107 ,  H01L31/109

Abstract: An apparatus, including: a probe to interface with a surface of a tissue; a light source optically coupled to the probe, the light source directing light of at least 1000 nm into the tissue; a detector optically coupled to the probe, the detector to detect light based on scattering of light from the light source in the tissue, and the detector having a light sensitivity in a range of at least 1000 nm; a processor coupled to the detector, the processor to: receive a signal from the detector corresponding to the detected light from the light source, and determine a blood flow measurement from the region of interest using diffuse correlation spectroscopy based on the signal.

公开(公告)号：US20190261869A1

公开(公告)日：2019-08-29

申请号：US16349405

申请日：2017-11-14

Applicant: THE GENERAL HOSPITAL CORPORATION

Inventor： Maria A. Franceschini ,  Parisa Farzam ,  Davide Tamborini ,  David Boas

IPC: A61B5/026 ,  A61B5/00 ,  A61B5/1455

Abstract: The present disclosure provides systems and methods for multi-distance, multi-wavelength diffuse correlation spectroscopy (MD-MW DCS). The systems and methods can include two, three, or more different wavelengths and two, three, or more different source-detector distances. The dynamics of a target medium can be determined using detected signals at the different wavelengths and different source-detector distances.