PLATE
    2.
    发明申请
    PLATE 审中-公开

    公开(公告)号:US20180119078A1

    公开(公告)日:2018-05-03

    申请号:US15854355

    申请日:2017-12-26

    Abstract: An analytical device includes a plate including a first substrate having a front surface and a back surface and a second substrate facing the back surface of the first substrate such that at least one detection space observable from outside is formed between the second substrate and the back surface of the first substrate, and an adapter. The first substrate has a first port having a through hole formed through the front surface and communicated with the detection space for delivering a liquid-containing substance into the detection space, the first substrate has a second port having a through hole formed through the front surface and communicated with the detection space for discharging a liquid-containing substance or a gas from the detection space, and the adapter is attachable to and detachable from the first port and the second port, and the front surface of the first substrate without the adapter is flat.

    BIOMOLECULE ANALYSIS KIT AND BIOMOLECULE ANALYSIS METHOD
    3.
    发明申请
    BIOMOLECULE ANALYSIS KIT AND BIOMOLECULE ANALYSIS METHOD 审中-公开
    生物分子试剂盒和生物分子分析方法

    公开(公告)号:US20160333400A1

    公开(公告)日:2016-11-17

    申请号:US15221143

    申请日:2016-07-27

    Abstract: A biomolecule analysis kit includes a reaction container configured to perform an enzymatic reaction, the reaction container including a base portion which has a container-shaped portion and a low-adsorption structural portion which is provided on at least the inner surface of the container-shaped portion, the low-adsorption structural portion having an adsorption rate lower than the base portion at which at least one of a sample which becomes a target of analysis in the enzymatic reaction and a reagent for the enzymatic reaction is adsorbed thereonto, wherein a signal resulting from the enzymatic reaction is configured to be detected when the enzymatic reaction is performed in the reaction container.

    Abstract translation: 生物分子分析试剂盒包括配置成进行酶反应的反应容器,反应容器包括具有容器形状部分和至少设置在容器形状部分的内表面上的低吸附结构部分的基部 低吸附结构部分的吸附率低于在酶反应中成为分析对象的样品中的至少一种和酶反应试剂中的至少一种的吸附速率,其中产生的信号 在反应容器中进行酶反应时,酶反应被配置为检测。

    PLATE
    5.
    发明申请
    PLATE 有权

    公开(公告)号:US20220002645A1

    公开(公告)日:2022-01-06

    申请号:US17481354

    申请日:2021-09-22

    Abstract: A method for filling an analytical device includes providing a plate having a detection space or spaces and ports communicating with the space(s), fitting, into one of the ports, an adapter having a reagent fixed on an inner wall of the adapter such that a first end of the adapter is fitted into the port, and delivering a sample solution into the detection space(s) through the adapter such that the sample solution and reagent fill the detection space(s). The plate includes a first substrate, a second substrate, and a side wall such that the plate has the detection space(s) between the substrates and that the first substrate has the ports, the first and/or second substrates is formed of transparent material such that the detection space is observable from outside the plate, and the ports include a first port for delivering liquid-containing substance, and a second port for discharging the substance.

    MICROFLUIDIC DEVICE AND SAMPLE ANALYSIS METHOD

    公开(公告)号:US20210394185A1

    公开(公告)日:2021-12-23

    申请号:US17464114

    申请日:2021-09-01

    Abstract: A microfluidic device including a microwell array having microwells, and a cover member facing the microwell array with a gap between the cover member and the microwell array, and having a flow path formed in the gap. The cover member has a surface facing the microwell array, and the surface has an arithmetic average roughness Ra of 70 nm or less.

    ANALYSIS DEVICES, ANALYSIS KITS, AND ANALYSIS SYSTEMS

    公开(公告)号:US20190060897A1

    公开(公告)日:2019-02-28

    申请号:US16173102

    申请日:2018-10-29

    Abstract: An analysis apparatus including a stage, an analysis device placed on the stage and including receiving sections which accommodate a sample and a reagent for biochemical reaction, and are communicated with one another through a flow path having an inlet and an outlet, a liquid introduction section which is connected to the inlet and supplies into the flow path the sample, the reagent, and an sealing liquid for sealing each of the receiving sections, and a waste liquid storage section which is connected to the outlet and stores as waste liquid an excess of the sample and the reagent and a part of the sealing liquid supplied to the flow path, an optical system which includes an objective lens, emits excitation light to the receiving sections and allows observation of fluorescence generated in the receiving sections by the excitation light, and a control unit that controls such that the sealing liquid and the excess of the sample and the reagent form an interface in the waste liquid storage section, and that the interface is formed at a distance not less than a fluorescence-obtainable distance from a bottom of the receiving sections.

    MICROFLUIDIC DEVICE AND SAMPLE ANALYSIS METHOD

    公开(公告)号:US20210387194A1

    公开(公告)日:2021-12-16

    申请号:US17458642

    申请日:2021-08-27

    Abstract: A microfluidic device including a substrate having at least one droplet holder formed thereon, and a cover member facing the substrate with a space between the cover member and the substrate, and having a flow path formed in the space and connected to the droplet holder. The flow path has a height of more than 0 μm and 30 μm or less.

    BIOMOLECULE ANALYSIS METHOD
    10.
    发明申请

    公开(公告)号:US20220290222A1

    公开(公告)日:2022-09-15

    申请号:US17751031

    申请日:2022-05-23

    Abstract: A biomolecule analysis method may include preparing a reaction container comprising an array of a plurality of micropores in which a wash buffer is filled or preparing the reaction container and feeding the wash buffer into the reaction container including the array of the plurality of micropores. The method may include feeding a reaction reagent to detect a sample, into the plurality of micropores, the sample including a biomolecule. The method may include feeding a sealing solution to seal the plurality of micropores so that the plurality of micropores become a plurality of independent reaction chambers sealed from each other. The method may include causing an isothermal detection reaction in each of the plurality of the independent reaction containers. The method may include detecting a signal amplified by the isothermal detection reaction.

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