公开(公告)号：US20240030017A1

公开(公告)日：2024-01-25

申请号：US18224460

申请日：2023-07-20

Applicant: Trace Matters Scientific LLC

Inventor： Mazdak Taghioskoui

IPC: H01J49/06 ,  G01N27/622

CPC classification number: H01J49/062 ,  H01J49/068 ,  G01N27/622

Abstract: A system that includes two analytical system utilizing charged particles, an ion transfer device that connects the two analytical systems and transports the charged particles from one of the analytical systems to the other of the analytical systems. The ion transfer device includes a plurality of differential pumping stages, a plurality of vacuum pumps, and a plurality of ion guides located inside the plurality of differential pumping stages such that the plurality of ion guides transport the charged particles from one to the other of the analytical systems, and such that the plurality of differential pumping stages connect the first analytical system on one end to the second analytical system on the other end to receive the charged particles from the one end connected to the first analytical system and transport and deliver the charged particles to the other end connected to the second analytical system.

公开(公告)号：US11222776B1

公开(公告)日：2022-01-11

申请号：US17071458

申请日：2020-10-15

Applicant: Trace Matters Scientific LLC

Inventor： Mazdak Taghioskoui

IPC: H01J49/06 ,  G01N27/62 ,  G01N27/622

Abstract: An ion analysis system includes one or more ionization sources that produce ions, one or more analyzers that analyze the ions based on ion mobility or mass to charge ratio of the ions, and one or more ion transfer devices connected between the one or more ionization sources and the one or more analyzers, the one or more ion transfer devices include a plurality of electrodes that are configured to be flexible or flexibly connected to each other, and the one or more ion transfer devices are configured to be flexible or re-configurable while transferring the ions.

公开(公告)号：US20200015717A1

公开(公告)日：2020-01-16

申请号：US16509016

申请日：2019-07-11

Applicant: Trace Matters Scientific LLC

Inventor： Mazdak Taghioskoui

IPC: A61B5/1473 ,  H01J49/00 ,  H01J49/36 ,  H01J49/16 ,  G01N27/62 ,  G01N33/483 ,  H01J49/06 ,  A61B5/00 ,  A61B10/04

Abstract: A method of analysis using mass spectrometry or ion mobility spectrometry that includes producing ions from a sample in a proximity of the sample, transferring the produced ions from the sample to a distance with a flexible or re-configurable ion guide, the flexible or re-configurable ion guide being connected to RF voltages, and separating the produced ions with a mass to charge or mobility analyzer located at the distance to provide spectrometric results; and detecting the separated ions with at least one detector.

公开(公告)号：US11756779B2

公开(公告)日：2023-09-12

申请号：US17570279

申请日：2022-01-06

Applicant: Trace Matters Scientific LLC

Inventor： Mazdak Taghioskoui

IPC: H01J49/06 ,  G01N27/62 ,  G01N27/622

CPC classification number: H01J49/062 ,  G01N27/622 ,  H01J49/068

Abstract: An apparatus includes a tubular connector having a longitudinal axis. The connector includes a first end that connects to a first analytical system, a second end that connects to a second analytical system, and a flexible portion between the first end and the second end that curves in a direction transverse to the axis of the connector such that the connector contains ion guides to transfer ions between the first analytical system and the second analytical system.

公开(公告)号：US11219393B2

公开(公告)日：2022-01-11

申请号：US16509016

申请日：2019-07-11

Applicant: Trace Matters Scientific LLC

Inventor： Mazdak Taghioskoui

IPC: A61B5/1473 ,  H01J49/36 ,  H01J49/16 ,  G01N27/622 ,  G01N33/483 ,  H01J49/06 ,  H01J49/00 ,  A61B5/00 ,  A61B10/04 ,  H01J49/04 ,  H01J49/42 ,  A61B18/00 ,  A61B18/24

Abstract: A method for analyzing biological samples using mass spectrometry or ion mobility spectrometry that includes producing gas-phase ions and neutrals from the sample in a proximity of the sample; transferring the produced ions from the sample to a distance via a flexible or re-configurable ion transfer device such that the flexible or re-configurable ion transfer device includes a plurality of electrodes configured to be flexible or flexibly connected to each other, and the ion transfer device is configured to be flexible while transferring the ions to allow the ion transfer device to form one or more curvatures; and separating the produced ions with a mass spectrometer or a mobility analyzer located at the distance to provide spectrometric results.

公开(公告)号：US10720315B2

公开(公告)日：2020-07-21

申请号：US16151162

申请日：2018-10-03

Applicant: Trace Matters Scientific LLC

Inventor： Mazdak Taghioskoui

IPC: H01J49/06 ,  H01J49/04 ,  H01J49/00

Abstract: An ion transfer device that transfers ions from at least one ion inlet to at least one ion outlet. The ion transfer device includes an enclosure configured to maintain reduced pressure, and a plurality of electrodes disposed at least in part inside the enclosure such that the ion transfer device is configured to be flexible or re-configurable.

公开(公告)号：US20240389905A1

公开(公告)日：2024-11-28

申请号：US18789390

申请日：2024-07-30

Applicant: Trace Matters Scientific LLC

Inventor： Mazdak Taghioskoui

IPC: A61B5/1473 ,  A61B5/00 ,  A61B10/04 ,  A61B18/00 ,  A61B18/24 ,  G01N27/622 ,  G01N33/483 ,  H01J49/00 ,  H01J49/06 ,  H01J49/16 ,  H01J49/36 ,  H01J49/42

Abstract: A method of analysis using mass spectrometry or ion mobility spectrometry that includes producing ions from a sample in a proximity of the sample, transferring the produced ions from the sample to a distance with a flexible or re-configurable ion guide, the flexible or re-configurable ion guide being connected to RF voltages, and separating the produced ions with a mass to charge or mobility analyzer located at the distance to provide spectrometric results; and detecting the separated ions with at least one detector.

公开(公告)号：US12080539B2

公开(公告)日：2024-09-03

申请号：US18224460

申请日：2023-07-20

Applicant: Trace Matters Scientific LLC

Inventor： Mazdak Taghioskoui

IPC: H01J49/06 ,  G01N27/62 ,  G01N27/622

CPC classification number: H01J49/062 ,  G01N27/622 ,  H01J49/068

Abstract: A system that includes two analytical system utilizing charged particles, an ion transfer device that connects the two analytical systems and transports the charged particles from one of the analytical systems to the other of the analytical systems. The ion transfer device includes a plurality of differential pumping stages, a plurality of vacuum pumps, and a plurality of ion guides located inside the plurality of differential pumping stages such that the plurality of ion guides transport the charged particles from one to the other of the analytical systems, and such that the plurality of differential pumping stages connect the first analytical system on one end to the second analytical system on the other end to receive the charged particles from the one end connected to the first analytical system and transport and deliver the charged particles to the other end connected to the second analytical system.

公开(公告)号：US20220208536A1

公开(公告)日：2022-06-30

申请号：US17570279

申请日：2022-01-06

Applicant: Trace Matters Scientific LLC

Inventor： Mazdak Taghioskoui

IPC: H01J49/06 ,  G01N27/622

Abstract: A high throughput mass spectrometry system that includes one or more sample preparation devices located at one or more of first locations configured to prepare samples for mass spectrometry analysis; one or more ionization sources configured to produce ions from the prepared samples at the one or more of the first locations; one or more mass spectrometers located at one or more of second locations configured to analyze the produced ions from the prepared samples based on mass to charge ratio of the produced ions; and one or more ion transfer devices configured to transfer the produced ions from the one or more of the first locations to the one or more of the second locations.

公开(公告)号：US20220202317A1

公开(公告)日：2022-06-30

申请号：US17570235

申请日：2022-01-06

Applicant: Trace Matters Scientific LLC

Inventor： Mazdak Taghioskoui

IPC: A61B5/1473 ,  A61B5/00 ,  A61B10/04 ,  G01N27/622 ,  G01N33/483 ,  H01J49/00 ,  H01J49/04 ,  H01J49/06 ,  H01J49/16 ,  H01J49/36 ,  H01J49/42

Abstract: A mass spectrometry imaging system includes an ionization source located at a first location configured to produce ions from a surface of a sample at the first location; a mass spectrometer located at a second location configured to perform mass spectrometry analysis by analyzing the produced ions based on mass to charge ratio of the ions; and an ion transfer device configured to transfer the ions from the first location to the second location such that the ion transfer device includes a plurality of electrodes, the plurality of electrodes configured to be flexible or flexibly connected to each other, and the ion transfer device is configured to be flexible or re-configurable while transferring the ions.