公开(公告)号：US11869176B2

公开(公告)日：2024-01-09

申请号：US17427890

申请日：2020-01-31

Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA

Inventor： Wen Shi ,  Eun Sang Koo ,  Scott E. Fraser ,  Francesco Cutrale

IPC: G06T5/10 ,  G01J3/28 ,  G06T5/00 ,  A61B5/00

CPC classification number: G06T5/10 ,  G01J3/2823 ,  G06T5/002 ,  A61B5/0075 ,  A61B5/441 ,  G06T2207/10024 ,  G06T2207/20056

Abstract: This invention relates to a hyperspectral imaging system for denoising and/or color unmixing multiple overlapping spectra in a low signal-to-noise regime with a fast analysis time. This system may carry out Hyper-Spectral Phasors (HySP) calculations to effectively analyze hyper-spectral time-lapse data. For example, this system may carry out Hyper-Spectral Phasors (HySP) calculations to effectively analyze five-dimensional (5D) hyper-spectral time-lapse data. Advantages of this imaging system may include: (a) fast computational speed, (b) the ease of phasor analysis, and (c) a denoising algorithm to obtain the minimally-acceptable signal-to-noise ratio (SNR). An unmixed color image of a target may be generated. These images may be used in diagnosis of a health condition, which may enhance a patient's clinical outcome and evolution of the patient's health.