公开(公告)号：US20190209606A1

公开(公告)日：2019-07-11

申请号：US16333434

申请日：2017-09-14

Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION

Inventor： Hamidreza GHANDEHARI ,  Siam OOTTAMASATHIEN ,  Mark Martin JENSEN ,  Joseph CAPPELLO ,  Wanjian JIA ,  Glenn D. PRESTWICH

IPC: A61K31/737 ,  A61K9/00 ,  A61K9/06 ,  A61K31/728 ,  A61K47/42 ,  A61K45/06 ,  A61P29/00

CPC classification number: A61K31/737 ,  A61K9/0019 ,  A61K9/06 ,  A61K31/728 ,  A61K45/06 ,  A61K47/36 ,  A61K47/42 ,  A61P29/00 ,  C07K14/78

Abstract: Described herein are in situ gelling compositions. The compositions include an anti-inflammatory polysaccharide and a gelling polymer, wherein the composition is a liquid prior to administration to a subject but converts to a gel upon administration to the subject. The compositions described herein have numerous applications with respect to the local treatment (reduction or prevention) of inflammation and/or tissue damage.

公开(公告)号：US20160361349A1

公开(公告)日：2016-12-15

申请号：US15205093

申请日：2016-07-08

Applicant: University of Utah Research Foundation

Inventor： Glenn D. PRESTWICH ,  Siam OOTTAMASATHEIN ,  Thomas P. KENNEDY

IPC: A61K31/737 ,  A61Q11/00 ,  A61K8/73 ,  A61K45/06

CPC classification number: A61K8/735 ,  A61K31/737 ,  A61K45/06 ,  A61Q11/00 ,  A61Q19/08 ,  A61K2300/00

Abstract: Described herein is the use of partially and fully sulfated hyaluronan or the pharmaceutically acceptable salt or ester thereof for therapeutic and cosmetic applications as well as the treatment of a number of systemic, dermatological, periodontal, ophthalmic, and urological inflammatory diseases.