公开(公告)号：US20190209606A1

公开(公告)日：2019-07-11

申请号：US16333434

申请日：2017-09-14

Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION

Inventor： Hamidreza GHANDEHARI ,  Siam OOTTAMASATHIEN ,  Mark Martin JENSEN ,  Joseph CAPPELLO ,  Wanjian JIA ,  Glenn D. PRESTWICH

IPC: A61K31/737 ,  A61K9/00 ,  A61K9/06 ,  A61K31/728 ,  A61K47/42 ,  A61K45/06 ,  A61P29/00

CPC classification number: A61K31/737 ,  A61K9/0019 ,  A61K9/06 ,  A61K31/728 ,  A61K45/06 ,  A61K47/36 ,  A61K47/42 ,  A61P29/00 ,  C07K14/78

Abstract: Described herein are in situ gelling compositions. The compositions include an anti-inflammatory polysaccharide and a gelling polymer, wherein the composition is a liquid prior to administration to a subject but converts to a gel upon administration to the subject. The compositions described herein have numerous applications with respect to the local treatment (reduction or prevention) of inflammation and/or tissue damage.