公开(公告)号：US20190021342A1

公开(公告)日：2019-01-24

申请号：US16072137

申请日：2017-01-20

Applicant: King Abdullah University of Science and Technology

Inventor： Heribert Hirt ,  Axel de Zelicourt ,  Maged Saad

IPC: A01N63/02 ,  C12N1/20 ,  A01H5/10 ,  C12R1/05 ,  C12R1/12

Abstract: It has been discovered that the desert endophytic bacterium SA187 SA187 can provide resistance or tolerance to abiotic stress conditions to seeds or plants. Compositions containing SA187 can be used to enhance plant development and yield under environmental stress conditions.

公开(公告)号：US20160262402A1

公开(公告)日：2016-09-15

申请号：US14775858

申请日：2014-03-17

Applicant: SPOGEN BIOTECH INC.

Inventor： Brian Thompson ,  Katie Thompson ,  Brittany Angle

IPC: A01N63/02 ,  C12R1/05 ,  C12R1/125 ,  C12R1/07 ,  C12R1/01 ,  C12R1/085

CPC classification number: A01N63/00 ,  A01H3/00 ,  A01N63/02 ,  C12R1/01 ,  C12R1/05 ,  C12R1/07 ,  C12R1/075 ,  C12R1/085 ,  C12R1/125 ,  A01N25/00

Abstract: The present invention generally relates to bacteriologically pure bacterial cultures of novel strains of plant growth-promoting bacteria, and inoculums comprising the same. The invention is also directed to plant seeds coated with the inoculums, kits comprising the inoculums and methods for stimulating plant growth by applying the biologically pure bacterial culture or the inoculum to a plant, plant seed, or plant growth medium.

公开(公告)号：US20050255570A1

公开(公告)日：2005-11-17

申请号：US10516987

申请日：2003-05-28

Applicant: Lars Zander ,  Stefan Busch ,  Carolin Meyer ,  Sabine Both ,  Ulrich Schoerken

Inventor： Lars Zander ,  Stefan Busch ,  Carolin Meyer ,  Sabine Both ,  Ulrich Schoerken

IPC: C12P7/64 ,  C12R1/05

CPC classification number: C12P7/6427

Abstract: Processes for preparing conjugated linoleic acid are described wherein a conjugated linoleic acid lower alkyl ester is subjected to hydrolysis in the presence of an enzyme to form a hydrolyzate comprising a conjugated linoleic acid and a lower alkanol, wherein at least a portion of the lower alkanol is continuously removed; the hydrolyzate is separated into an organic phase and an aqueous/alcoholic phase; and the conjugated linoleic acid is separated from the organic phase.

Abstract translation: 描述制备共轭亚油酸的方法，其中共轭亚油酸低级烷基酯在酶存在下进行水解以形成包含共轭亚油酸和低级链烷醇的水解产物，其中至少一部分低级烷醇为 连续删除 将水解产物分离成有机相和水相/醇相; 共轭亚油酸与有机相分离。

公开(公告)号：US06137007A

公开(公告)日：2000-10-24

申请号：US373862

申请日：1999-08-13

Applicant: Christine Bernegger ,  Eva Maria Urban ,  Olwen Mary Birch ,  Knut Burgdorf ,  Frank Brux ,  Kay-Sara Etter ,  Pierre Bossard ,  Walter Brieden ,  Laurent Duc ,  John Gordon ,  Colm O'Murchu ,  Yves Guggisberg

Inventor： Christine Bernegger ,  Eva Maria Urban ,  Olwen Mary Birch ,  Knut Burgdorf ,  Frank Brux ,  Kay-Sara Etter ,  Pierre Bossard ,  Walter Brieden ,  Laurent Duc ,  John Gordon ,  Colm O'Murchu ,  Yves Guggisberg

IPC: C12P41/00 ,  C07C231/18 ,  C07C231/20 ,  C07C233/23 ,  C07C271/24 ,  C07D209/94 ,  C07D233/04 ,  C07D233/74 ,  C07D235/02 ,  C07D237/06 ,  C07D239/70 ,  C07D473/40 ,  C12P13/00 ,  C12P13/02 ,  C12P17/18 ,  C12R1/01 ,  C12R1/05 ,  C12R1/06 ,  C12R1/09 ,  C12R1/19 ,  C12R1/38 ,  C07C215/42

CPC classification number: C07C231/18 ,  C07C233/23 ,  C07C271/24 ,  C07D209/94 ,  C12P13/001 ,  C12P13/02 ,  C12P17/182 ,  C07B2200/07 ,  C07C2101/10

Abstract: A novel process for the preparation of (1S,4R)- or (1R,4S)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol of the formulae ##STR1## is described. This entails in the first stage (.+-.)-2-azabicyclo[2.2.1]hept-5-en-3-one of the formula ##STR2## being acylated to give a (.+-.)-2-azabicyclo[2.2.1]hept-5-en-3-one derivative of the general formula ##STR3## in which R.sup.1 denotes C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy, aryl or aryloxy, the latter being reduced in the second stage to give a cyclopentene derivative of the general formula ##STR4## in which R.sup.1 has the stated meaning, the latter then being converted in the third stage biotechnologically into the (1R,4S)- or (1S,4R)-1-amino-4-(hydroxymethyl)-2-cyclopentene of the formula ##STR5## the latter being converted in the fourth stage with N-(2-amino-4,6-dichloro-5-pyrimidinyl)formamide of the formula ##STR6## into the (1S,4R)- or (1R,4S)-4-[(2-amino-6-chloro-5-formamido-4-pyrimidinyl)amino]-2-cyclopentene-1-methanol of the formulae ##STR7## and the latter being cyclized in the fifth stage in a known manner to the final product of the formula I or II.

Abstract translation: 制备式（1S，4R） - 或（1R，4S）-4-（2-氨基-6-氯-9H-嘌呤-9-基）-2-环戊烯-1-甲醇的新方法， 被描述。 这需要在被酰化的式（+/-）-2-氮杂双环[2.2.1]庚-5-烯-3-酮的第一阶段中得到（+/-）-2-氮杂双环[2.2.1 ]庚-5-烯-3-酮衍生物，其中R 1表示C 1-4 - 烷基，C 1-4 - 烷氧基，芳基或芳氧基，后者在第二阶段中还原，得到 其中R 1具有所述含义的通式，后者在第三阶段中生物技术转化为（1R，4S） - 或（1S，4R）-1-氨基-4-（羟甲基）-2-环戊烯 式（1R，4S）-4 - （（1S，4R） - 或（1R，4S）-4 - 2-氨基-6-氯-5-甲酰氨基-4-嘧啶基）氨基] -2-环戊烯-1-甲醇，后者在第五阶段以已知方式环化为式I的最终产物 或II。

公开(公告)号：US5959091A

公开(公告)日：1999-09-28

申请号：US917925

申请日：1986-10-10

Applicant: Lidia S. Watrud ,  Frederick J. Perlak

Inventor： Lidia S. Watrud ,  Frederick J. Perlak

IPC: A01G13/00 ,  A01C1/00 ,  A01N63/00 ,  C07K14/325 ,  C12N1/20 ,  C12N1/21 ,  C12N15/00 ,  C12N15/09 ,  C12N15/78 ,  C12P21/02 ,  C12R1/01 ,  C12R1/05 ,  C12R1/07 ,  C12R1/18 ,  C12R1/20 ,  C12R1/22 ,  C12R1/38 ,  C12R1/39 ,  C07H21/04

CPC classification number: C07K14/325 ,  A01N63/00 ,  C12N15/78

Abstract: The invention relates to genetically engineered plant-colonizing microorganisms which prolife-rate in symbiotic or non-detrimental relationships with the plant in the plant environment. Such microorganisms contain DNA derived from Bacillus thuringiensis which codes for the insecticidal crystal protein toxin. The engineered plant-colonizing microorganisms of the invention and their progeny are active against a variety of lepidopterous pests. The invention further relates to the use of such plant-colonizing microorganisms in a method of killing or inhibiting lepidopterous pests and to insecticidal compositions containing the plant-colonizing microorganism as the active insecticidal agent.

Abstract translation: 本发明涉及与植物环境中的植物共生或非有害关系的遗传工程植物定植微生物。 这样的微生物含有源自苏云金芽孢杆菌的DNA，其编码杀虫晶体蛋白毒素。 本发明的工程植物定植微生物及其后代对各种鳞翅目害虫具有活性。 本发明还涉及这种植物定植微生物在杀死或抑制鳞翅目害虫的方法中的用途以及含有植物定植微生物作为活性杀虫剂的杀虫组合物。

公开(公告)号：US5891703A

公开(公告)日：1999-04-06

申请号：US793229

申请日：1997-04-23

Applicant: Jan M. Van Der Laan ,  Adriana M. Riemens ,  Wilhelmus J. Quax

Inventor： Jan M. Van Der Laan ,  Adriana M. Riemens ,  Wilhelmus J. Quax

IPC: C12N15/09 ,  C12N1/15 ,  C12N9/84 ,  C12N15/00 ,  C12N15/55 ,  C12P35/02 ,  C12P37/06 ,  C12R1/05 ,  C12R1/745 ,  C12R1/80 ,  C12N15/11 ,  C12N15/70

CPC classification number: C12P35/02 ,  C12N9/84 ,  C12P37/06

Abstract: New mutant .beta.-lactam Penicillin G acylases are provided, exhibiting altered substrate specificities. These Penicillin G acylases are obtained by expression of a gene encoding for said Penicillin G acylase and having an amino acid sequence which differs at least in one amino acid from the wild-type Penicillin G acylase.

Abstract translation: PCT No.PCT / EP95 / 03249 Sec。 371日期1997年4月23日 102（e）日期1997年4月23日PCT提交1995年8月14日PCT公布。 出版物WO96 / 05318 日期1996年2月22日提供新的突变体β-内酰霉素青霉素G酰基转移酶，表现出改变的底物特异性。 这些青霉素G酰基转移酶是通过表达编码所述青霉素G酰基转移酶的基因并具有至少在一个氨基酸中与野生型青霉素G酰基转移酶不同的氨基酸序列获得的。

公开(公告)号：US5489432A

公开(公告)日：1996-02-06

申请号：US129609

申请日：1993-09-30

Applicant: Jewel M. Payne ,  M. Keith Kennedy ,  John B. Randall ,  David O. Brower ,  H. Ernest Schnepf

Inventor： Jewel M. Payne ,  M. Keith Kennedy ,  John B. Randall ,  David O. Brower ,  H. Ernest Schnepf

IPC: C12N15/09 ,  A01N63/00 ,  A01N63/02 ,  C07K14/325 ,  C12N1/20 ,  C12N1/21 ,  C12P21/02 ,  C12R1/01 ,  C12R1/02 ,  C12R1/05 ,  C12R1/065 ,  C12R1/07 ,  C12R1/18 ,  C12R1/22 ,  C12R1/38 ,  C12R1/41 ,  C12R1/425 ,  C12R1/465 ,  A01N25/00

CPC classification number: C12R1/075 ,  A01N63/00 ,  C07K14/325

Abstract: The subject invention concerns a novel microbe and genes encoding novel toxin proteins with activity against cockroaches. Cockroaches are common house pests, and they create problems in hospitals, the food industry and in agriculture. The novel Bacillus thuringiensis microbe of the invention is referred to as B.t. PS185L8. The subject invention also concerns the use of B.t. PS201T6 to control cockroaches. A truncated form of a toxin obtained from PS201T6 having particular activity to cockroaches is also claimed for use in controlling the pest. The spores or crystals of the two microbes, or mutants thereof, are useful to control cockroaches in various environments. The genes of the invention can be used to transform various hosts wherein the novel toxic proteins can be expressed.

Abstract translation: 本发明涉及新型微生物和编码具有抗蟑螂活性的新型毒素蛋白质的基因。 蟑螂是常见的家蝇，它们在医院，食品工业和农业中造成问题。 本发明的新型苏云金芽孢杆菌微生物称为B.t. PS185L8。 本发明还涉及使用B.t. PS201T6控制蟑螂。 从PS201T6获得的具有蟑螂特定活性的截短形式的毒素也被要求用于防治害虫。 两种微生物的孢子或晶体或其突变体可用于控制各种环境中的蟑螂。 本发明的基因可用于转化其中可以表达新的有毒蛋白质的各种宿主。

公开(公告)号：US5286486A

公开(公告)日：1994-02-15

申请号：US973320

申请日：1992-11-06

Applicant: Jewel M. Payne ,  Jenny M. Fu

Inventor： Jewel M. Payne ,  Jenny M. Fu

IPC: A01N37/44 ,  A01N63/00 ,  A01N63/02 ,  C07K14/195 ,  C07K14/32 ,  C07K14/325 ,  C07K14/41 ,  C12N1/21 ,  C12N5/10 ,  C12N15/00 ,  C12N15/09 ,  C12N15/32 ,  C12R1/01 ,  C12R1/02 ,  C12R1/05 ,  C12R1/07 ,  C12R1/18 ,  C12R1/38 ,  C12R1/41 ,  C12R1/425 ,  C12R1/465 ,  C12P21/06 ,  C07H15/00

CPC classification number: C12R1/075 ,  A01N63/00 ,  C07K14/325 ,  Y10S435/832

Abstract: Certain known and available strains of Bacillus thuringiensis (B.t.) have been found to have activity against coleopteran pests. Previously, these strains were not known to have any insecticidal properties. The B.t. strains can be used in various environments to control coleopteran pests, e.g., the Colorado Potato Beetle. Also described are novel toxins, and genes coding for these toxins, which have coleopteran activity.

Abstract translation: 已经发现某些已知和可用的苏云金芽孢杆菌（B.t.）菌株具有抗鞘翅目害虫的活性。 以前，这些菌株不知道具有任何杀虫性质。 B.t. 菌株可用于各种环境中以控制鞘翅目害虫，例如科罗拉多马铃薯甲虫。 还描述了新的毒素和编码这些毒素的基因，其具有鞘翅目的活性。

公开(公告)号：US5212089A

公开(公告)日：1993-05-18

申请号：US631091

申请日：1990-12-19

Applicant: Toshio Suzuki ,  Naoya Kasai

Inventor： Toshio Suzuki ,  Naoya Kasai

IPC: C12P7/18 ,  C12P41/00 ,  C12R1/05

CPC classification number: C12R1/05 ,  C12P41/001 ,  C12P7/18 ,  Y10S435/829

Abstract: A process for preparation of S-(+)-3-halogeno-1,2-propanediol which comprises cultivating a bacterium, which has an ability to assimilate R-(-)-3-halogeno-1,2-propanediol and belongs to the genus Alcaligenes, or its culture broth in a medium containing racemate 3-halogeno-1,2-propanediol, and recovering S-(+)-3-halogeno-1,2-propanediol from the resulting culture broth.

公开(公告)号：US5182197A

公开(公告)日：1993-01-26

申请号：US830844

申请日：1992-02-04

Applicant: Andreas Kiener ,  Rainer Glockler ,  Klaus Heinzmann

Inventor： Andreas Kiener ,  Rainer Glockler ,  Klaus Heinzmann

IPC: C12P7/42 ,  C12N1/20 ,  C12P17/10 ,  C12P17/12 ,  C12R1/01 ,  C12R1/05 ,  C12R1/07 ,  C12R1/38

CPC classification number: C12R1/05 ,  C12P17/12 ,  Y10S435/822 ,  Y10S435/829 ,  Y10S435/874

Abstract: A microbiological process for the production of 6-hydroxypicolinic acid starting from picolinic acid and/or its salts. The concentration of picolinic acid and/or its salts is selected so that the 6-hydroxypicolinic acid is not further metabolized. The process is performed either by microorganisms of genus Pseudomonas, Bacillus, Alcaligenes, Aerococcus, or Rhodotorula, or with biomass using picolinic acid, which grow with picolinic acid as the sole carbon, nitrogen and energy source.

Abstract translation: 从吡啶甲酸和/或其盐开始生产6-羟基吡啶甲酸的微生物过程。 选择吡啶甲酸和/或其盐的浓度使得6-羟基吡啶甲酸不被进一步代谢。 该方法由假单胞菌属，芽孢杆菌属，产碱杆菌属，Aerococcus属或红酵母属的微生物或与使用吡啶甲酸作为唯一碳，氮和能源生长的吡啶甲酸的生物质进行。