Quality Control of High Performance Superconductor Tapes

    公开(公告)号:US20220406986A1

    公开(公告)日:2022-12-22

    申请号:US17865860

    申请日:2022-07-15

    Abstract: A superconductor tape and method for manufacturing, measuring, monitoring, and controlling same are disclosed. Embodiments are directed to a superconductor tape which includes a superconductor film overlying a buffer layer which overlies a substrate. In one embodiment, the superconductor film is defined as having a c-axis lattice constant higher than 11.74 Angstroms. In another embodiment, the superconductor film comprises BaMO3, where M=Zr, Sn, Ta, Nb, Hf, or Ce, and which has a (101) peak of BaMO3 elongated along an axis that is between 60° to 90° from an axis of the (001) peaks of the superconductor film. These and other embodiments achieve well-aligned nanocolumnar defects and thus a high lift factor, which can result in superior critical current performance of the tape in, for example, high magnetic fields.

    Compositions, methods and kits for treating a contact lens

    公开(公告)号:US11529309B2

    公开(公告)日:2022-12-20

    申请号:US16096603

    申请日:2017-04-28

    Abstract: Provided herein are fluorinated compounds having chemical structures: (I) where n is 0 or greater, or (II) where m and n are 0 or greater, or an amino acid, a soluble polymer, an oligo(ethylene glycol), a poly(ethylene glycol), or a carbohydrate each fluorinated with perfluorocarbons having the chemical structure (III) where n is 0 or greater. These fluorinated compounds are utilized in contact lenses to impart lipid-resistant, protein-resistant and biofouling-resistant properties, thus reducing discomfort and infection caused by contact lens wear without changing its transmission characteristics. Also provided is an ophthalmic drug delivery system comprising at least one of the compounds described above embedded in the contact lens and a kit to incorporate the ophthalmic into a contact lens. Methods for incorporating these compounds onto a contact lens without affecting transparency and for use in treating an ophthalmologic-associated condition are provided.

    Systems and methods for continuous objective assessment of near work

    公开(公告)号:US11375890B2

    公开(公告)日:2022-07-05

    申请号:US16229458

    申请日:2018-12-21

    Inventor: Lisa Ostrin

    Abstract: Systems and methods for continuous objective assessment are discussed herein. The systems and methods may comprise sensor(s), a processor, a clock, data storage, and a power source. The sensor(s) may continuously monitor viewing distances, light exposure, or the like, and the system may log corresponding time and/or duration information. Also provided herein are methods of treating, preventing, and/or diagnosing vision impairment risk. These systems and methods may provide warns, such as when detecting the viewing of materials too closely (e.g. ≤30 cm), near to near intermediate viewing (e.g. ≤70 cm) exceeding a predetermined time (e.g. ≥20 min.) without a break, and/or not getting enough outdoor light exposure (e.g. at least 75 minutes of exposure at >1000 lux) for the day.

    METHODS OF IMPROVING THE LONGEVITY OF IMMUNE CELLS

    公开(公告)号:US20220195389A1

    公开(公告)日:2022-06-23

    申请号:US17604714

    申请日:2020-04-17

    Abstract: Embodiments of the present disclosure pertain to methods of modifying immune cells by increasing the AMP-activated protein kinase (AMPK) activity of the immune cells in order to produce modified immune cells with enhanced longevity. In some embodiments, the methods of the present disclosure include one or more of the following steps: (1) obtaining immune cells from a subject; (2) increasing the AMPK activity of the immune cells; (3) expanding the modified immune cells; (4) introducing the modified immune cells to a subject; and (5) treating a disease in the subject. In further embodiments, the methods of the present disclosure include an in vivo method of increasing the AMPK activity of immune cells in a subject in order to treat a disease in the subject. Additional embodiments of the present disclosure pertain to the modified immune cells.

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