흑염소의 프리온 단백질을 코딩하는 유전자를 포함하는 발현 벡터 및 이에 의하여 형질도입된 세포
    91.
    发明公开
    흑염소의 프리온 단백질을 코딩하는 유전자를 포함하는 발현 벡터 및 이에 의하여 형질도입된 세포 有权
    表达载体包含来自CAPRA AEGAGRUS HIRCUS和转移细胞的基因编码蛋白质

    公开(公告)号:KR1020140081447A

    公开(公告)日:2014-07-01

    申请号:KR1020120151209

    申请日:2012-12-21

    Abstract: The present invention relates to an expression vector comprising a gene encoding a prion protein of Capra hircus and a cell transduced by the vector. The present invention can be used for manufacturing a cell having polymorphism, which represents Capra hircus bred in Korea, and a transduced mouse; and can be effectively used for developing an animal experimental model for studies including diagnosis of prion diseases which include scrapie occurred in goat family animals, and for confirming if domestic TSE diseases interspecifically spread or not.

    Abstract translation: 本发明涉及一种表达载体,其包含编码Capra hircus的朊病毒蛋白的基因和由载体转导的细胞。 本发明可用于制造具有多形性的细胞,其代表在韩国繁殖的Capra hircus和转导的小鼠; 可以有效地用于研究包括诊断朊病毒疾病的动物实验模型,包括山羊家族动物发生的瘙痒病,以及确认国内TSE疾病是否特异性传播。

    웨스트나일바이러스 유지 및 검출용 배지와 이를 이용한 웨스트나일바이러스 검출 또는 역가검정법
    92.
    发明公开
    웨스트나일바이러스 유지 및 검출용 배지와 이를 이용한 웨스트나일바이러스 검출 또는 역가검정법 无效
    用于检测和维护西尼病毒的介质和使用其的西兰病毒的检测和测序方法

    公开(公告)号:KR1020120086024A

    公开(公告)日:2012-08-02

    申请号:KR1020110007213

    申请日:2011-01-25

    CPC classification number: C12Q1/045 C12N7/00 G01N31/221 G01N33/52

    Abstract: PURPOSE: A medium for maintainig and determining west nile is provided to reduce the exposure by high risk virus and to shorten the use of harmful reagents. CONSTITUTION: A medium for maintaining and detecting west nile contains alpha-MEM or DMEM containing 1-10 g/L of glucose and pH indicator. The pH indicator is phenol red. A potency assay method for detecting west nile comprises: a step of culturing west nile host cells and a sample in the medium; and a step of measuring the pH concentration of the medium to detecting west nile virus and tittering west nile in a sample. The host cells are monkey kidney cells.

    Abstract translation: 目的:提供维护和确定西尼罗河的介质,以减少高风险病毒的暴露并缩短有害试剂的使用。 构成:用于维持和检测西尼罗河的培养基含有含有1-10克/升葡萄糖和pH指示剂的α-MEM或DMEM。 pH指示剂为酚红。 用于检测西尼罗河的效力测定方法包括:培养西尼罗河宿主细胞和培养基中的样品的步骤; 以及测定介质中检测西尼罗病毒并滴定样品中西尼罗河的pH浓度的步骤。 宿主细胞是猴肾细胞。

    복분자 추출물을 포함하는 소해면상뇌증의 예방 또는 치료용 조성물
    93.
    发明公开
    복분자 추출물을 포함하는 소해면상뇌증의 예방 또는 치료용 조성물 无效
    包含RUBI FRUCTUS提取物的组合物,用于预防或治疗BOVINE SPONIFORM ENCEPHALOPATHY

    公开(公告)号:KR1020120075678A

    公开(公告)日:2012-07-09

    申请号:KR1020100137439

    申请日:2010-12-29

    CPC classification number: A61K36/73 A23V2200/322 A61K2236/331 A61K2236/333

    Abstract: PURPOSE: A composition containing Rubi Fructus extract is provided to inhibit modified prion production and to prevent or treat BSE. CONSTITUTION: A veterinary composition for preventing or treating BSE contains Rubi Fructus extract. The extract is prepared using water, low alcohol of C1-C4, and a mixture solvent thereof. The concentration of the extract is 6.25ug/ml. The daily dose of the composition is 0.0001-100 mg/kg. A feed additive composition for preventing or treating BSE contains the extract. A feed contains the extract.

    Abstract translation: 目的:提供含有Rubi Fructus提取物的组合物,以抑制修饰的朊病毒生成并预防或治疗BSE。 组成:用于预防或治疗疯牛病的兽用组合物含有Rubi Fructus提取物。 提取物是使用水,C1-C4的低级醇及其混合溶剂制备的。 提取物的浓度为6.25ug / ml。 组合物的日剂量为0.0001-100mg / kg。 用于预防或治疗BSE的饲料添加剂组合物含有提取物。 Feed包含提取物。

    유전자재조합 돼지열병 백신바이러스 Flc―LOM―BErns virus 및 이의 제조방법
    96.
    发明公开
    유전자재조합 돼지열병 백신바이러스 Flc―LOM―BErns virus 및 이의 제조방법 无效
    遗传重组人兽毒病毒感染者FLC-LOM-BERNS病毒及其制备方法

    公开(公告)号:KR1020100121288A

    公开(公告)日:2010-11-17

    申请号:KR1020090040368

    申请日:2009-05-08

    Abstract: PURPOSE: A vaccine virus for swine fever of gene recombination is provided to easily detect mutation of vaccine virus and to early remove infected pig. CONSTITUTION: A vaccine virus for swine fever, Flc-LOM-BErns virus(KFCC11442P) contains a nucleotide of sequence number 1. An Erns gene of CSFV(classical swine fever virus) is substituted with Erns gene of BVDV(bovine viral disease virus) in the vaccine virus. The vaccine virus is Erns gene marker, Erns serologic marker or END(Exaltaton of Newcastle Disease virus) bio marker. A method for manufacturing swine vaccine virus, Flc-LOM-BErns virus(KFCC11442P) comprises: a step of extracting genomic RNA from swine fever virus strain; a step of synthesizing full-length cDNA to total RNA; a step of removing Erns gene from the synthesized cDNA; and a step of inserting Erns gene of BVDV.

    Abstract translation: 目的:提供用于猪瘟基因重组的疫苗病毒,以便于检测疫苗病毒的突变并及早清除感染猪。 构成:用于猪瘟的疫苗病毒Flc-LOM-BErns病毒(KFCC11442P)含有序列号1的核苷酸。将CSFV(经典猪瘟病毒)的Erns基因用BVDV(牛病毒病毒)的Erns基因取代, 在疫苗病毒中。 疫苗病毒是Erns基因标记,Erns血清学标记或END(新城疫病毒Exaltaton)生物标志物。 一种制造猪疫苗病毒Flc-LOM-BErns病毒(KFCC11442P)的方法包括:从猪瘟病毒株中提取基因组RNA的步骤; 将全长cDNA合成到总RNA中的步骤; 从合成的cDNA中除去Erns基因的步骤; 和插入BVDV的Erns基因的步骤。

    구제역 바이러스의 감염여부를 진단하는 방법 및 이를구현하기 위한 진단키트
    98.
    发明公开
    구제역 바이러스의 감염여부를 진단하는 방법 및 이를구현하기 위한 진단키트 有权
    用于诊断国内动物脚部和口腔疾病的方法,包括反应部分,条带,试验样品引导部分和壳体的快速和诊断试剂盒

    公开(公告)号:KR1020040095824A

    公开(公告)日:2004-11-16

    申请号:KR1020030026809

    申请日:2003-04-28

    Abstract: PURPOSE: A method for diagnosis of foot and mouth disease and a diagnostic kit are provided, thereby rapidly and accurately diagnosing foot and mouth disease with a small amount of a sample, and easily and rapidly diagnosing foot and mouth disease of domestic animals in the field. CONSTITUTION: The method for diagnosis of foot and mouth disease comprises the steps of: (1) introducing a testing sample into a loading area of a strip; (2) combining a detecting reagent with a marker with a target material in the sample to prepare a complex; (3) developing the complex on a membrane; and (4) measuring the appearance change of a reaction portion having one or more fixing phase selected from antigen, antibody or hapten which is obtainable through the immune reaction from FMDV in a certain region of the membrane. The diagnostic kit comprises a reaction portion(13) having one or more fixing phase selected from antigen, antibody or hapten which is obtainable through the immune reaction from FMDV; a strip(1') having a control portion for determining normal operation on a certain region; a testing sample introducing portion; and a housing with a displaying window(4) for displaying reaction results in the reaction portion(13) and the control portion. on the strip(1').

    Abstract translation: 目的:提供口蹄疫诊断方法和诊断试剂盒,用少量样品快速,准确地诊断口蹄疫,容易快速诊断现场家畜的口蹄疫 。 规定:口蹄疫诊断方法包括以下步骤:(1)将检测样品引入条带的装载区域; (2)将检测试剂与标记物与样品中的靶材料组合以制备复合物; (3)在膜上显影复合物; 和(4)测量具有一个或多个定影相的反应部分的外观变化,所述固定相选自抗原,抗体或半抗原,所述抗原,抗体或半抗原可通过膜的某一区域中的FMDV通过免疫反应获得。 诊断试剂盒包括具有选自抗原,抗体或半抗原的一个或多个固定相的反应部分(13),其可通过FMDV的免疫反应获得; 具有用于确定某一区域正常操作的控制部分的条带(1'); 测试样品引入部分; 以及具有用于在反应部(13)和控制部显示反应结果的显示窗(4)的壳体。 在条带(1')上。

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