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公开(公告)号：KR1020100086215A
公开(公告)日：2010-07-30
申请号：KR1020090005455
申请日：2009-01-22
Applicant: 대한민국(농촌진흥청장)
IPC: G01N21/359 , G01N33/02
Abstract: PURPOSE: A method for quantifying campesterol of soybean using NIRL is provided to usefully use for developing a material for a high quality resource, breeding or industry by rapidly searching vegetable sterol content per unit weight of soybean. CONSTITUTION: A method for quantifying campesterol of soybean using NIRL is as follows. A soybean seed classified based on the species is added to a test tube in a powdered state and is inserted into a NIRL(near infrared light) analyzer. The NIRL is radiated and an absorption spectrum of 1700 to 2100nm is obtained. A first differentiation is applied to the near-infrared spectrum. A first derivative value is obtained where gap per wave has 10nm. The campesterol content in the soybean sample is determined using the first derivative value per wave.
Abstract translation: 目的：通过快速检索大豆单位重量的植物甾醇含量，通过NIRL定量大豆油菜酯的方法，有效地用于开发优质资源，育种或工业用材料。 构成：使用NIRL量化大豆油菜酯的方法如下。 将基于该物种分类的大豆种子以粉末状加入到试管中并插入NIRL（近红外光）分析仪中。 NIRL被辐射，并且获得1700至2100nm的吸收光谱。 对近红外光谱应用第一个区别。 获得一个导数值，其中每波的间隙为10nm。 大豆样品中的菜油甾醇含量使用每波的一阶导数值确定。
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92.发明授权
公开(公告)号：KR100905219B1
公开(公告)日：2009-07-01
申请号：KR1020070087608
申请日：2007-08-30
Applicant: 대한민국(농촌진흥청장)
Abstract: 본 발명은 자가 절단 2A배열을 포함하는 베타카로틴 생합성용 융합 폴리뉴클레오티드 및 이를 이용한 형질전환 식물체에 관한 것으로서 보다 상세하게는 파이토엔 합성 효소, FMDV 유래 2A 서열 및 박테리아 카로틴 불포화 효소를 암호화하는 융합 폴리뉴클레오티드 및 이를 이용한 형질전환 식물체에 관한 것이다. 본 발명의 융합 폴리뉴클레오티드 및 이를 이용한 재조합 벡터는 형질전환된 세포 내에서 안정적으로 파이토엔 합성효소 및 카로틴 불포화 효소를 발현할 수 있는 효과를 갖는다. 따라서 본 발명의 융합 폴리뉴클레오티드는 베타카로틴 생합성을 위하여 식물체의 대사과정의 조절의 목적으로 사용할 수 있을 뿐만 아니라, 이로 인해 유용한 대사산물인 베타카로틴 함량의 증진의 목적으로 사용할 수 있다.
유전자 다중 발현, 2A 배열, 파이토엔 합성 효소, 카로틴 불포화 효소, 베타카로틴, 벼, 쌀-
93.发明公开
公开(公告)号：KR1020090022328A
公开(公告)日：2009-03-04
申请号：KR1020070087608
申请日：2007-08-30
Applicant: 대한민국(농촌진흥청장)
Abstract: A fusion polynucleotide with self-cleaving 2A arrangement is provided to control a metabolism process of a plant for beta-carotene biosynthesis, thereby increasing the contents of beta-carotene. A fusion polynucleotide with self-cleaving 2A arrangement encodes hot pepper phytoene synthase consisting of base sequences indicated as a sequence number 1, rice plant opimization FMDV-derived 2A sequence, and bacteria carotene desaturase. A recombinant vector for transformation comprises a promoter and the fusion polynucleotide operably connected to the promoter. The recombinant vector is a pGlb-PAC vector.
Abstract translation: 提供具有自我裂解2A排列的融合多核苷酸以控制植物的β-胡萝卜素生物合成的代谢过程，从而增加β-胡萝卜素的含量。 具有自切割2A排列的融合多核苷酸编码由序列号1表示的碱基序列，水稻植物优化的FMDV衍生的2A序列和细菌胡萝卜素去饱和酶组成的辣椒八味子合成酶。 用于转化的重组载体包含与启动子可操作地连接的启动子和融合多核苷酸。 重组载体是pGlb-PAC载体。
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94.发明公开3,4,5-트리히드록시벤즈알데히드를 유효성분으로 포함하는고지혈증 및 ＭＭＰ 과다활성으로 인한 혈관질환 예방 및치료용 조성물 有权用于包含3,4,5-三羟基苯甲醛作为活性成分的高活性MMP的预防和治疗高脂血症和血管疾病的组合物
公开(公告)号：KR1020090020279A
公开(公告)日：2009-02-26
申请号：KR1020070084916
申请日：2007-08-23
Applicant: 대한민국(농촌진흥청장)
Abstract: A composition comprising 3,4,5-trihydroxybenzaldehyde is provided to increase blood high density cholesterol, reduce the amount of neutral fat, and inhibit MMP(matrix metalloproteinase) activity of arterial vascular smooth muscle cell, thereby preventing and treating hyperlipidemia and vascular disease such as arteriosclerosis. The pharmaceutical composition for preventing and treating hyperlipidemia and vascular disease due to highly activated MMP comprises 3,4,5-trihydroxybenzaldehyde separated from Geum japonicum THUNBERG or pharmaceutically acceptable salts thereof, wherein the vascular disease due to highly activated MMP is selected from arteriosclerosis, angina, myocardial infarction, hypertension, anemia, migraine, stroke and hemandioma.
Abstract translation: 提供包含3,4,5-三羟基苯甲醛的组合物以增加血液中的高密度胆固醇，减少中性脂肪的量，并抑制动脉血管平滑肌细胞的MMP（基质金属蛋白酶）活性，从而预防和治疗高脂血症和血管疾病 作为动脉硬化。 用于预防和治疗由高度活化的MMP引起的高脂血症和血管疾病的药物组合物包括从天麻日本THUNBERG分离的3,4,5-三羟基苯甲醛或其药学上可接受的盐，其中由高度活化的MMP引起的血管疾病选自动脉硬化，心绞痛 ，心肌梗塞，高血压，贫血，偏头痛，中风和血管瘤。
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95.发明授权
公开(公告)号：KR100718602B1
公开(公告)日：2007-06-21
申请号：KR1020050133322
申请日：2005-12-29
Applicant: 대한민국(농촌진흥청장)
Abstract: An extract of Geum japonicum having anti-obesity and anti-inflammation effects, a food composition comprising the same extract and a preparation method of the same extract are provided to inhibit obesity by suppressing accumulation of neutral fat and GPDH(glycerol-3-phosphate dehydrogenase) activity, and inhibit inflammation by suppressing production of NO(nitrogen oxide) as an inflammation factor, and initial inflammatory cytokines of PGE2(Prostaglandin E), IL(interleukin)-1beta and TNF(tumor necrosis factor)-alpha. The method for preparing the extract of Geum japonicum having anti-obesity and anti-inflammation effects comprises the steps of: (1) extracting dried powder of Geum japonicum with methanol or ethanol, filtering the extract, and concentrating the filtered solution to obtain the methanol or ethanol extract; (2) adding hexane and water into the methanol or ethanol extract, separating a hexane layer and a water layer(i) and concentrating the hexane layer to obtain the hexane extract; (3) adding methylene chloride and water into the water layer(i), separating a methylene chloride layer and a water layer(ii) and concentrating the methylene chloride layer to obtain the methylene chloride extract; (4) adding ethyl acetate and water into the water layer(ii), separating an ethyl acetate layer and a water layer(iii) and concentrating the ethyl acetate layer to obtain the ethyl acetate extract; and (5) evaporating the water from the water layer(iii) to obtain the water layer.
Abstract translation: 提供一种具有抗肥胖和抗炎作用的金盏花提取物，包含该提取物的食品组合物以及该提取物的制备方法，以通过抑制中性脂肪和GPDH（甘油-3-磷酸脱氢酶 ）活性，并通过抑制作为炎症因子的NO（氮氧化物）的产生和PGE2（前列腺素E），IL（白细胞介素）-1β和TNF（肿瘤坏死因子）-α的最初炎性细胞因子来抑制炎症。 制备具有抗肥胖和抗炎作用的锦extract提取物的方法包括以下步骤：（1）用甲醇或乙醇提取锦鲤干燥粉末，过滤提取物，浓缩滤液得到甲醇 或乙醇提取物; （2）向甲醇或乙醇提取物中加入己烷和水，分离己烷层和水层（i），浓缩己烷层得到己烷提取物; （3）向水层（i）中加入二氯甲烷和水，分离二氯甲烷层和水层（ii），浓缩二氯甲烷层得到二氯甲烷提取物; （4）将乙酸乙酯和水加入水层（ii）中，分离乙酸乙酯层和水层（iii），浓缩乙酸乙酯层得到乙酸乙酯提取物; 和（5）从水层（iii）蒸发水以获得水层。
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Patent Agency Ranking
公开(公告)号：KR1019960009742B1
公开(公告)日：1996-07-24
申请号：KR1019940004134
申请日：1994-03-03
Applicant: 대한민국(농촌진흥청장)
Abstract: The extraction method of edible oil (I) from plant Thalictrum Linne (II) consists of (1) crushing freeze-dried (II), and (2) extracting with chloroform and methanol. The edible seed oil is extracted by : freezing-drying Thalictrum Linne seed; pulverizing and utrasonicating to obtain the seed powder; extracting oil from the powder with chloroform and methanol; and purifying the extracted oil to obtain the final product. The seed oil has unsaturated fatty acid e.g. delta5-trans-linoleic acid.
Abstract translation: 植物枸杞（II）食用油（I）的提取方法为（1）粉碎冷冻干燥（II），（2）用氯仿和甲醇萃取。 可食用的种子油是通过以下方式提取的：冷冻干燥的Thalictrum Linne种子; 粉碎和松散以获得种子粉末; 用氯仿和甲醇从粉中提取油; 并纯化提取的油以获得最终产物。 种子油具有不饱和脂肪酸，例如 δ5-反式亚油酸。
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公开(公告)号：KR1020170139721A
公开(公告)日：2017-12-20
申请号：KR1020160071651
申请日：2016-06-09
Applicant: 대한민국(농촌진흥청장)
Abstract: 본발명은항산화활성을가지는신선초분말을포함하는선식조성물및 이를이용한영양바에관한것으로, 더욱상세하게는신선초분말에적합한선식베이스를혼합함으로서, 관능적효과및 분산성이우수한, 항산화활성을가지는신선초분말을포함하는선식조성물및 이를이용한영양바에관한것이다. 본발명에따른선식조성물은추출물이아닌분말형태로신선초를포함하기때문에신선초의영양소를모두섭취할수 있고, 항산화활성이우수하며, 신선초분말의관능특성및 분산성을향상시킬수 있는선식베이스조성물을포함함으로서색, 향, 맛및 전반적기호도등의관능특성이매우우수하고, 분산성도우수하다.
Abstract translation: 具有金属丝的组合物和涉及它们与营养棒，通过更具体地涉及适合于当归keiskei粉末的混合线基本发明当归keiskei粉末，感觉效果和分散性是优异的，抗氧化活性，包括具有抗氧化活性当归keiskei粉末 和使用相同的营养棒。 由于根据本发明的导线组合物包括当归keiskei粉末形式，而不是提取物和可消耗当归keiskei的所有营养物质，和抗氧化活性yiwoosu，通过包括基于有线的组合物，可以提高当归keiskei粉末的功能特性和分散性 它具有优良的感官特性，例如颜色，风味，味道和一般口感，并且分散性优异。
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公开(公告)号：KR101740502B1
公开(公告)日：2017-05-30
申请号：KR1020150157776
申请日：2015-11-10
Applicant: 대한민국(농촌진흥청장)
Abstract: 본발명은참죽나무(. Juss.) 추출물을유효성분으로함유하는숙취해소용약학적조성물에관한것으로, 구체적으로참죽나무 70% 발효주정추출물을수득하였고, 상기참죽나무추출물을간 세포주에처리한후 에탄올로세포손상을유도한결과세포생존율이증가함을확인하였으며, 참죽나무추출물이알코올분해효소활성을증가시키는것을확인함으로써, 본발명의참죽나무추출물은숙취해소예방용조성물로유용하게이용될수 있다.
Abstract translation: 本发明chamjuk树之后（久事。）涉及所述提取物解酒物质的药物组合物含有作为活性成分的，被具体地，得到chamjuk树70％发酵醇提取物，加工chamjuk叶之间的细胞系 引线与乙醇的细胞损伤后发现，细胞活力增加，通过确保为chamjuk树提取物提高了醇的分解活性，本发明的木chamjuk提取物可以有利地用作组合物用于预防宿醉 。
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公开(公告)号：KR1020170055099A
公开(公告)日：2017-05-19
申请号：KR1020150157782
申请日：2015-11-10
Applicant: 대한민국(농촌진흥청장)
IPC: A61K36/537 , A23L1/30
Abstract: 본발명은배암차즈기(R.Br.) 추출물을유효성분으로함유하는숙취해소용약학적조성물에관한것으로, 구체적으로배암차즈기잎과뿌리에서 70% 발효주정추출물을수득하였고, 상기배암차즈기추출물을간암세포주에처리한후 에탄올로세포손상을유도한결과세포생존율이증가함을확인하였으며, 배암차즈기잎 추출물이알코올분해효소활성을증가시키는것을확인함으로써, 본발명의배암차즈기추출물은숙취해소예방용조성물로유용하게이용될수 있다.
Abstract translation: 本发明baeam车jeugi（R.Br.）涉及含有该提取物作为有效成分的物质的宿醉药物组合物，以从发酵具体地说baeam chajeu GIIP和根，baeam茶提取物jeugi得到70％乙醇提取物 一个治疗肝癌细胞系后可确认得到的细胞生存力的细胞乙醇被增加，以诱导损伤，baeam chajeu GIIP提取物通过检查以增加醇分解活性，本发明的宿醉车baeam提取jeugi 并且可以有效地用作预防性组合物。
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