公开(公告)号：DE59910677D1

公开(公告)日：2004-11-04

申请号：DE59910677

申请日：1999-11-12

Applicant: BASF AG

Inventor： VON DEYN WOLFGANG ,  GEBHARDT JOACHIM ,  RACK MICHAEL ,  LOCHTMAN RENE ,  GOETZ NORBERT ,  KEIL MICHAEL ,  WITSCHEL MATTHIAS ,  HAGEN HELMUT ,  MISSLITZ ULF ,  BAUMANN ERNST

IPC: C07C251/40 ,  C07C251/48 ,  C07C319/14 ,  C07C323/09 ,  C07D261/04 ,  C07D261/08 ,  C07D413/10

Abstract: The present invention describes a process for preparing isoxazoles of the formula Iwhere:R is hydrogen, C1-C6-alkyl,R is hydrogen, C1-C6-alkyl,R , R , R are each hydrogen, C1-C6-alkyl or R and R together form a bond,R is a heterocyclic ring,n is 0, 1 or 2;which comprises preparing an intermediate of the formula VIwhere R , R , R and R are each as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I.Furthermore, the invention describes novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates.

公开(公告)号：NZ524049A

公开(公告)日：2004-09-24

申请号：NZ52404901

申请日：2001-07-17

Applicant: BASF AG

Inventor： LOCHTMAN RENE ,  KEIL MCIHAEL ,  GEBHARDT JOACHIM ,  RACK MICHAEL ,  VON DEYN WOLFGANG

IPC: C07B61/00 ,  C07C319/14 ,  C07C323/62 ,  C07D261/04 ,  C07D413/04 ,  C07C251/40 ,  C07D413/10

Abstract: A process for preparing 4-thioalkylbromobenzene derivatives such as 4-methylthio-3-(4,5-dihydroisoxazol-3-yl)-2-methylbromobenzene of the formula (I) is disclosed, wherein: R1 is C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-haloalkoxy, C3-C8-cycloalkyl or a halogen; R2 is C1-C6-alkyl, C1-C6-alkoxy, C3-C8-cycloalkyl, C2-C6-alkenyl, cyano or a heterocyclic radical; R3 is C1-C6-alkyl; which comprises reacting a compound of the formula (II), in which R1 and R2 are as defined above, with a dialkyl disulfide of the formula (III) in the presence of a nitrite such as sodium nitrite and a catalyst such as copper powder in a suitable solvent. The reaction may be carried out at temperatures between 30-100 degree C

公开(公告)号：SK462003A3

公开(公告)日：2003-07-01

申请号：SK462003

申请日：2001-07-17

Applicant: BASF AG

Inventor： LOCHTMAN RENE ,  KEIL MICHAEL ,  GEBHARDT JOACHIM ,  RACK MICHAEL ,  VON DEYN WOLFGANG

IPC: C07B61/00 ,  C07C319/14 ,  C07C323/62 ,  C07D261/04 ,  C07D413/04 ,  C07C251/40 ,  C07D413/10

Abstract: A process for preparing 4-thioalkylbromobenzene derivatives of the formula I where: R 1 is C 1 -C 6 -alkyl, C 1 -C 6 -haloalkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -haloalkoxy, C 3 -C 8 -cycloalkyl, halogen, R 2 is C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, C 3 -C 8 -cycloalkyl, C 2 -C 6 -alkenyl, cyano or a heterocyclic radical, R 3 is C 1 -C 6 -alkyl, which comprises reacting a compound of the formula II, in which R 1 and R 2 are as defined above, with a dialkyl disulfide of the formula III R 3 -S-S-R 3 III in the presence of a nitrite and a catalyst in a suitable solvent is described.

公开(公告)号：DE59808163D1

公开(公告)日：2003-06-05

申请号：DE59808163

申请日：1998-01-08

Applicant: BASF AG

Inventor： RHEINHEIMER JOACHIM ,  DEYN WOLFGANG VON ,  GEBHARDT JOACHIM ,  HILL LUISE ,  RACK MICHAEL ,  KOENIG HARTMANN ,  GOETZ NORBERT ,  MAYWALD VOLKER ,  KARDORFF UWE

IPC: C07D231/20 ,  C07D261/04 ,  C07D261/20 ,  C07D413/10 ,  C07D417/10

Abstract: PCT No. PCT/EP98/00066 Sec. 371 Date Jul. 13, 1999 Sec. 102(e) Date Jul. 13, 1999 PCT Filed Jan. 8, 1998 PCT Pub. No. WO98/31676 PCT Pub. Date Jul. 23, 1998Sulfur-containing 2-chloro-3-(4,5-dihydro-3-isoxazolyl)-benzoic acids of the formula I in which the substituents have the meanings given in the description are prepared as described.

公开(公告)号：NO20030212L

公开(公告)日：2003-01-16

申请号：NO20030212

申请日：2003-01-16

Applicant: BASF AG

Inventor： LOCHTMAN RENE ,  KEIL MICHAEL ,  GEBHARDT JOACHIM ,  RACK MICHAEL ,  DEYN WOLFGANG VON

IPC: C07B61/00 ,  C07C319/14 ,  C07C323/62 ,  C07D261/04 ,  C07D413/04

Abstract: A process for preparing 4-thioalkylbromobenzene derivatives of the formula I where: R 1 is C 1 -C 6 -alkyl, C 1 -C 6 -haloalkyl, C 1 -C 6 -alkoxy, C 1 -C 6 -haloalkoxy, C 3 -C 8 -cycloalkyl, halogen, R 2 is C 1 -C 6 -alkyl, C 1 -C 6 -alkoxy, C 3 -C 8 -cycloalkyl, C 2 -C 6 -alkenyl, cyano or a heterocyclic radical, R 3 is C 1 -C 6 -alkyl, which comprises reacting a compound of the formula II, in which R 1 and R 2 are as defined above, with a dialkyl disulfide of the formula III R 3 -S-S-R 3 III in the presence of a nitrite and a catalyst in a suitable solvent is described.

公开(公告)号：NO20026201A

公开(公告)日：2002-12-23

申请号：NO20026201

申请日：2002-12-23

Applicant: BASF AG

Inventor： LOCHTMAN RENE ,  KEIL MICHAEL ,  GEBHARDT JOACHIM ,  RACK MICHAEL ,  DEYN WOLFGANG VON

IPC: C07C209/74 ,  C07C211/52 ,  C07D261/04

CPC classification number: C07D261/04

公开(公告)号：SI0888261T1

公开(公告)日：2002-04-30

申请号：SI9730182

申请日：1997-03-06

Applicant: BASF AG

Inventor： EICKEN KARL ,  GEBHARDT JOACHIM ,  RANG HARALD ,  RACK MICHAEL ,  SCHAEFER PETER

IPC: C07B37/04 ,  C07C201/12 ,  C07C205/06 ,  C07C205/11 ,  C07C205/12 ,  C07C205/35

公开(公告)号：ZA200007286B

公开(公告)日：2001-12-10

申请号：ZA200007286

申请日：2000-12-08

Applicant: BASF AG

Inventor： RHEINHEIMER JOACHIM ,  DEYN WOLFGANG VON ,  GEBHARDT JOACHIM ,  RACK MICHAEL ,  LOCHTMAN RENE ,  GOETZ NORBERT ,  KEIL MICHAEL ,  WITSCHEL MATTHIAS ,  HAGEN HELMUT ,  MISSLITZ ULF ,  BAUMANN ERNST

IPC: C07C20060101 ,  C07D20060101 ,  C07D413/10 ,  C07C ,  C07D

公开(公告)号：CZ20004167A3

公开(公告)日：2001-07-11

申请号：CZ20004167

申请日：1999-05-04

Applicant: BASF AG

Inventor： RHEINHEIMER JOACHIM ,  VON DEYN WOLFGANG ,  GEBHARDT JOACHIM ,  RACK MICHAEL ,  LOCHTMAN RENE ,  HAGEN HELMUT ,  MISSLITZ ULF ,  BAUMANN ERNST ,  GOTZ NORBERT ,  KEIL MICHAEL ,  WITSCHEL MATTHIAS

IPC: C07C20060101 ,  C07C201/12 ,  C07C205/44 ,  C07C249/06 ,  C07C251/48 ,  C07C251/52 ,  C07C253/00 ,  C07C255/50 ,  C07C317/32 ,  C07C319/14 ,  C07C323/09 ,  C07D20060101 ,  C07D261/02 ,  C07D261/04 ,  C07D261/08 ,  C07D413/02 ,  C07D413/10

公开(公告)号：AU1651500A

公开(公告)日：2000-06-05

申请号：AU1651500

申请日：1999-11-12

Applicant: BASF AG

Inventor： DEYN WOLFGANG VON ,  GEBHARDT JOACHIM ,  RACK MICHAEL ,  LOCHTMAN RENE ,  GOTZ NORBERT ,  KEIL MICHAEL ,  WITSCHEL MATTHIAS ,  HAGEN HELMUT ,  MISSLITZ ULF ,  BAUMANN ERNST

IPC: C07D261/04 ,  C07B61/00 ,  C07C251/40 ,  C07C319/14 ,  C07D413/10