公开(公告)号：JPH04312541A

公开(公告)日：1992-11-04

申请号：JP7527291

申请日：1991-04-08

Applicant: KAO CORP

Inventor： KAMIYA HIROSHI ,  KITA KATSUMI ,  FUJIKURA YOSHIAKI ,  YAHAGI KAZUYUKI

IPC: B01J23/04 ,  B01J31/02 ,  C07B61/00 ,  C07C31/22 ,  C07C41/03 ,  C07C43/13

Abstract: PURPOSE:To provide a new trimethylolalkane derivative producible in high purity without using formaldehyde undesirable to use from the safety point of view, exhibiting extremely excellent lubricity, easily and uniformly dispersible in water and useful as a base, emulsifier, lubricant, etc., for cosmetics, etc. CONSTITUTION:The trimethylolalkane derivative of formula I [n is integer of 0-4; A to A are H, -CH2CH(OH)CH2OR or group of formula II (R is 16-36C branched alkyl) provided that A to A are not H at the same time], e.g. monoether compound of trimethylol-propane glyceryl isostearyl ether. The compound of formula I can be produced by reacting a trimethylolalkane of formula III with a glycidyl ether of formula IV in an organic solvent in the presence of a basic catalyst.

公开(公告)号：JPH04145094A

公开(公告)日：1992-05-19

申请号：JP26760090

申请日：1990-10-05

Applicant: KAO CORP

Inventor： KITA KATSUMI ,  FUJIKURA YOSHIAKI

IPC: C07H15/04 ,  B01F17/56 ,  C11D1/66

Abstract: NEW MATERIAL:A compound expressed by formula I (G is 5-6C reducing sugar which may have a substituent, condensate of said reducing sugar or a residue obtained by removing n-pieces of OH from oligosaccharide containing said reducing sugar as a constructing unit; L is 1-24C bifunctional hydrocarbon which may have OH; R is 1-24C monofunctional hydrocarbon). EXAMPLE:1-O-glucopyranosyl-3-S-dodecylthioglycerol. USE:Useful as a detergent, emulsifier, dispersant, a wetting agent or a solubilizing agent, etc., for toiletry goods. PREPARATION:A compound expressed by formula II (X is halogen) or a compound expressed by formula III (M is 1-22C bifunctional hydrocarbon) is reacted with a compound expressed by the formula: RSH in the presence of an alkaline substance (e.g. sodium hydroxide).

公开(公告)号：JPH04103594A

公开(公告)日：1992-04-06

申请号：JP21904590

申请日：1990-08-22

Applicant: KAO CORP

Inventor： KITA KATSUMI ,  KAMIYA HIROSHI ,  FURUGAKI HISAKAZU ,  FUJIKURA YOSHIAKI

IPC: C07H15/04 ,  A61K8/00 ,  A61K8/60 ,  A61Q5/00 ,  A61Q5/02 ,  C07H15/06

Abstract: PURPOSE:To industrially advantageously obtain the subject compound suitable as a base agent of cosmetic or detergent, etc., in a low cost and high productivity by reacting a specific raw material compound with a specific compound of sodium laurate, etc. CONSTITUTION:A compound expressed by the formula G-(A)n [G is residue of saccharide selected from substitutable 5-6C reduced sugar, condensate of said sugar and substitutable oligosaccharide containing 5-6C reduced sugar a unit from which removed n-pieces of hydroxyl groups are removed; A is group expressed by formula I or formula II (X is halogen) as a group bonding to C-atom which formerly bonded with one of above-mentioned removed n-pieces of hydroxyl groups; (n) is a number from 1 to the number of hydroxyl groups in the saccharide] is made to react with a compound expressed by the formula RCOOM (R is linear 1-24C alkyl or alkenyl; M is H or cation) to afford the objective compound expressed by the formula G-(B)n (B and G are groups bonding to C-atom which formerly bonded with the above-mentioned n-pieces of hydroxyl groups and are expressed by formula III and formula IV, etc.).

公开(公告)号：JPH03174499A

公开(公告)日：1991-07-29

申请号：JP31465889

申请日：1989-12-04

Applicant: KAO CORP

Inventor： KAMETANI JUN ,  KAMIYA HIROSHI ,  KITA KATSUMI ,  KUROSAKI TOMIHIRO

IPC: A61K8/00 ,  A61K8/60 ,  A61Q5/02 ,  A61Q19/10 ,  C11D1/68

Abstract: PURPOSE:To obtain a detergent composition for washing body, hair or dishes, which is less irritative to skin and improved in foaming property as well as low-temperature stability by adding fructoside. CONSTITUTION:A detergent composition is obtained by adding a fructoside (preferably one represented by the formula, wherein R is 6-24C alkyl or alkenyl), which is effective as a non-ionic surfactant. Fructoside, which is obtained by allowing sucrose and a long-chain alcohol to react, is high in purity and improved in hue and low-temperature stability. A detergent composition containing such fructoside is less irritative to skin, light to the touch, and improved in foaming power, foam stability and low-temperature stability, and therefore, effective as an agent for washing skin, hair or dishes.

公开(公告)号：JPH02110198A

公开(公告)日：1990-04-23

申请号：JP26233388

申请日：1988-10-18

Applicant: KAO CORP

Inventor： UENO ASAKO ,  HORINISHI NOBUTAKA ,  KITA KATSUMI ,  KUROSAKI TOMIHIRO

IPC: C12N9/96 ,  C07K1/00 ,  C11D3/386

Abstract: PURPOSE:To stabilize a non-protease enzyme to thereby permit its utilization for detergents, dentifrice, shampoo, cosmetics, reagents for clinical laboratory test, drugs, etc., by incorporating a specified substance into an enzyme solution containing both protease and a non-protease enzyme. CONSTITUTION:An enzyme solution containing both protease and a non-protease enzyme preferably comprising a sugar-decomposing enzyme (e.g., cellulase) is mixed with a non-protease enzyme substrate or its analogue, or a non-protease enzyme inhibitor (e.g., a cellooligosaccharide, such as cellobiose, or its mixture; cellulose partially hydrolyzed with an acid or enzyme; a cellulose derivative, such as CMC, hydrolyzed with an enzyme or acid; or a chitosan oligomer).

公开(公告)号：JPH1180186A

公开(公告)日：1999-03-26

申请号：JP24815697

申请日：1997-09-12

Applicant: KAO CORP

Inventor： OKUTSU TAKAHISA ,  KITSUKI TOMOHITO ,  KITA KATSUMI

IPC: C07H1/00 ,  B01J31/02 ,  C07B61/00 ,  C07H15/04

Abstract: PROBLEM TO BE SOLVED: To obtain the subject compound useful as a surfactant low in skin irritativity in a state controlled in the condensation of a saccharide by reacting a higher alcohol with the saccharide in the presence of a specific aluminum compound as an acid catalyst. SOLUTION: This method for preparing an alkylglycoside comprises reacting a higher alcohol (e.g. decyl alcohol) with a saccharide (e.g. glucose) in the presence of an aluminum compound of the formula R is a (substituted) hydrocarbon group, a (substituted) hydrocarbonoxy group; (l), (m), (n) are each an integer wherein at least one of (l) and (n) is not zero, and (l)+(m)+(n)=3} as an acid catalyst, while controlling the self-condensation of the saccharide. Thus, the objective alkylglycoside useful as a surfactant low in skin irritativity, a foam stabilizer for anionic surfactants, and the like is obtained in an improved yield.

公开(公告)号：JPH10158207A

公开(公告)日：1998-06-16

申请号：JP25982597

申请日：1997-09-25

Applicant: KAO CORP

Inventor： UNO MITSURU ,  YANO SHINJI ,  TAMURA HIDEKO ,  FUJII YASUYUKI ,  KITA KATSUMI

IPC: B01J23/44 ,  C07B41/04 ,  C07B61/00 ,  C07C41/01 ,  C07C41/06 ,  C07C43/04 ,  C07C43/10 ,  C07C43/11

Abstract: PROBLEM TO BE SOLVED: To obtain the subject high-quality compound at one stage in high yield with suppressing side reactions occurring in a reaction by specifying an aldehyde adding method. SOLUTION: In reacting a hydroxy compound with an aldehyde by using a catalyst in a hydrogen atmosphere, the reaction is carried out while dripping at least a part of the aldehyde, preferably >=50wt.% of the whole amount of the aldehyde to a reaction system for 0.5-20 hours continuously and/or intermittently to give the objective compound. Preferably, the reaction is carried out while removing water formed as a by-product by the reaction. A palladium catalyst supported on carbon, etc., is used as the catalyst. A compound of formula I (R1 is a 1-40C alkyl, etc.; A is a 2-12C alkylene; (n) is 0-500) is used as the hydroxy compound and a compound of formula II (R2 is H, a 1-20C alkyl, etc.), preferably a compound such as a

公开(公告)号：JPH1036307A

公开(公告)日：1998-02-10

申请号：JP19184396

申请日：1996-07-22

Applicant: KAO CORP

Inventor： OKUTSU TAKAHISA ,  KITSUKI TOMOHITO ,  KITA KATSUMI

IPC: C07D301/26 ,  B01J31/02 ,  C07B61/00 ,  C07C41/03 ,  C07C43/13 ,  C07D303/22

Abstract: PROBLEM TO BE SOLVED: To enable to obtain a halohydrin ether useful as a raw material for synthesizing glycidyl ethers by using a specific catalyst in reacting an alcohol with an α-epihalohydrin. SOLUTION: This production method of a halohydrin ether is to use a catalyst consisting of an aluminum alkoxide (C1 ) such as aluminum triisopropoxide and a phenol or a sulfonic acid acid (C2 ) [e.g. a (halogen-substituted) phenol or naphthol, a (1-12C alkyl- or OH-substituted) benzensulfonic acid or naphthalenesulfuric ascid] when (A) an alcohol such as a compound of the formula; R-(OA)n -OH [R is 1-36C (un)saturated) hydrocarbon group; A is a 2-4C alkyrene; (b) is 0-100] is reacted with (B) an α-epihalohydrin. The resection so preferably carried out by using 0.001-0.1 made times of the ingredient C1 based on the ingredient A and 0.1-3.0 mole times of the ingredient C2 based on the integrated C1 .

公开(公告)号：JPH09301927A

公开(公告)日：1997-11-25

申请号：JP11603996

申请日：1996-05-10

Applicant: KAO CORP

Inventor： UNO MITSURU ,  TAMURA HIDEKO ,  FUJII YASUYUKI ,  KITA KATSUMI

IPC: A61K8/30 ,  A61K8/37 ,  A61Q1/00 ,  A61Q1/04 ,  B01J23/44 ,  C07B61/00 ,  C07C67/313 ,  C07C69/708 ,  A61K7/00

Abstract: PROBLEM TO BE SOLVED: To obtain a new compound excellent in skin affinity, etc., and useful as an oily raw material for cosmetics. SOLUTION: A compound of formula I [three R groups are each independently H, a group of formula II (R , R are each independently H, a 1-12C alkyl, etc.), wherein at least one of the R groups is the group of formula II]. For example, glycerol tri(12-isopropoxystearate). The compound of formula I is obtained by reacting a compound of formula III with castor oil or hardened castor oil in the presence of a catalyst such as palladium carried on carbon, etc., in the atmosphere of hydrogen, while removing water by-produced during the reaction.

公开(公告)号：JPH09202743A

公开(公告)日：1997-08-05

申请号：JP13823196

申请日：1996-05-31

Applicant: KAO CORP

Inventor： FUJII YASUYUKI ,  FURUGAKI HISAKAZU ,  MATSUMOTO YASUMASA ,  KITA KATSUMI

IPC: B01J23/44 ,  C07B61/00 ,  C07C41/01 ,  C07C41/06 ,  C07C43/04 ,  C07C43/11 ,  C07C43/184

Abstract: PROBLEM TO BE SOLVED: To easily and safely obtain an ether compound widely useful for solvents, cosmetics, detergent compositions, lubricants, emulsifiers, etc. SOLUTION: This ether compound (e.g. methyl alcohol, ethyl alcohol) is obtained by reaction between a hydroxy compound of formula I (R1 is a 1-40C alkyl, etc.; A is a 2-12C alkylene; (n) is 0-30) (e.g. methyl Cellosolve) and a carbonyl compound of formula II (R2 and R3 are each a 1-20C alkyl, alkenyl, etc.) (e.g. a 1-12C chain ketone) in a hydrogen atmosphere in the presence of a palladium catalyst borne on e.g. carbon. The reaction is pref. carried out while eliminating water as a by-product; specifically, the reaction is carried out in the presence of a dehydrating agent (e.g. anhydrous magnesium sulfate, anhydrous sodium sulfate) at 0.1-50mol% based on the final ether compound.