Abstract:
A sample holder comprises a spectral encoding material to encode a measurement signal of the sample with a spectral identification signal. The spectral encoding material has the advantage of providing an encoded signal with the measurement signal, which can help to ensure that the sample is appropriately identified. The sample holder may comprise one or more of a support, a container, a waveguide, or a substrate. The spectral encoding material may comprise a spectrally encoding solution, spectrally encoding particles, or one or more spectrally encoding layers of material. The spectral encoding material may comprise a calibration material, such as a polymer.
Abstract:
A laser-based spectroscopy system that combines a distance/proximity standoff sensor, a high-repetition rate laser spectroscopy system, and software with a decision-making algorithm embedded in a processing unit which in combination performs selective firing of the laser when the target object is within an interrogation zone. In a related embodiment, the system provides selective sorting of spectroscopic signals based on information from the standoff signal and from information contained in the spectral signals themselves. The laser emission can be actively controlled while keeping the laser firing, thereby preserving the thermal stability and hence the power of the laser; and the standoff sensor information and the spectral information can be combined to determine the proper relative weighting or importance of each piece of spectral information.
Abstract:
Devices, systems, and methods for measuring tissue oxygen saturation are disclosed. An illustrative spectrometer for interfacing an optical sensor with a display unit includes a number of measurement radiation sources, a number of radiation source fibers each optically coupled to one of the measurement radiation sources, a reflected radiation fiber optically coupled to the optical sensor, a measurement radiation output fiber including an image fiber, and a radiation mixing bar intermediate the radiation source fibers and the measurement radiation output fiber.
Abstract:
An optical assembly for use with a spectrophotometer. The optical assembly may comprise an illumination source, a detection sensor, a monitor sensor, and an optical piece having a first side adapted to face a sample. The optical piece may define an illumination channel extending from the illumination source toward the first side. The optical piece may also define a detection channel extending from the first side toward the detection sensor, hi addition, the optical piece may define a monitor channel extending from the illumination channel toward the monitor sensor. Also, a light emitting diode (LED) assembly for use with an optical measurement device. The LED assembly may comprise a substrate having a top surface and a bottom surface and a plurality of LED dies positioned on the substrate to emit light in a first direction normal to the bottom surface of the substrate. The LED assembly may also comprise a plurality of leads in electrical contact with the plurality of LED dies. The plurality of leads may be positioned on the bottom surface of the substrate, and may be configured to surface-mount to a board.
Abstract:
A coupling mechanism for mounting a sample accessory assembly (45) into a spectrometer (5). The accessory assembly (45), on which is mountable a sample to be analyzed by a spectrometer (5), has connector ends (3) which are insertable into stirrups (2) on the sample compartment (6) of the spectrometer (5). The connector ends (3) and the stirrups (2) have elements that ensure that the accessory assembly (45) is properly aligned in the sample compartment (6) of the spectrometer (5). The accessory assembly (45) also has an electronic component, such as a circuit or programmable microchip, that is connected to the spectrometer (5) when the accessory is mounted in the spectrometer (5). The electronic component provides information to the spectrometer (5) identifying the accessory assembly (45) being used so that a diagnostic test of the spectrometer (5) can be performed to ascertain, for example, proper mounting of the accessory assembly (45) in the spectrometer (5).
Abstract:
The spectrometer comprises a radiation source (1) whose radiation is focused on an entrance slit (5) of an echelle monochromator (6, 7, 8, 9, 10). A fibre optic bundle (52) has one end (51) located above a slot on the output plate (10) of the echelle monochromator and its other end (53) located adjacent an array detector (54). The fibre optic bundle (52) has a card (59) attached to it which specifies the respective positions of the ends of each fibre within the bundle. A card reader (58) reads this information and passes it to a memory (61). A microprocessor (57) is used to relate the outputs of a given detector element to a given wavelength of radiation using the information read from the card (59).
Abstract:
Systems and methods are provided for a UV-VIS spectrophotometer, such as a UV-VIS detector unit included in a high-performance liquid chromatography system. In one example, a system for the UV-VIS detector unit may include a first light source, a signal detector, a flow path positioned intermediate the first light source and the signal detector, a second light source, and a reference detector. The first light source, the signal detector, and the flow path may be aligned along a first axis, and the second light source and the reference detector may be aligned along a second axis, different than the first axis.
Abstract:
An imaging system includes a plurality of optical sensors arranged on an integrated circuit in an array with a plurality of rows and a plurality of columns. The system includes an interface communicating with the plurality of optical sensors, memory storing operational instructions and processing circuitry configured to sample an image using the plurality of optical sensors in a first mode and sample at least a portion of the image sequentially on a row-by-row basis at a predetermined sampling rate in a second mode to produce row by row sample outputs. The processing circuitry is further configured to initiate sampling at least some rows of the plurality of rows of optical sensors using different time stamps.
Abstract:
A system for non-invasively interrogating an in vivo sample for measurement of analytes comprises a pulse sensor coupled to the in vivo sample for detect a blood pulse of the sample and for generating a corresponding pulse signal, a laser generator for generating a laser radiation having a wavelength, power and diameter, the laser radiation being directed toward the sample to elicit Raman signals, a laser controller adapted to activate the laser generator, a spectrometer situated to receive the Raman signals and to generate analyte spectral data; and a computing device coupled to the pulse sensor, laser controller and spectrometer which is adapted to correlate the spectral data with the pulse signal based on timing data received from the laser controller in order to isolate spectral components from analytes within the blood of the sample from spectral components from analytes arising from non-blood components of the sample.
Abstract:
The disclosure provides improved processing of optical data by identifying anomalous signals in the electrical data representing the optical data. The improved processing can also include modifying the identified anomalous signal data to provide a truer representation of the optical data. The disclosed processing can be used by various systems and apparatuses for processing spectral data corresponding to the optical data. The improved processing can be used to improve the monitoring of semiconductor processes and, therefore, improve the overall semiconductor processes. In one example, a method of processing spectral data includes: (1) receiving temporally separated spectral data samples, and (2) identifying one or more anomalous signals in an intermediate one of the temporally separated spectral data samples based on at least one preceding and at least one subsequent ones of the spectral data samples.