公开(公告)号：FI970150A0

公开(公告)日：1997-01-14

申请号：FI970150

申请日：1997-01-14

Applicant: BASF AG

Inventor： HELLENDAHL BEATE ,  LANSKY ANNEGRET ,  MUNSCHAUER RAINER ,  BIALOJAN SIEGFRIED ,  UNGER LILIANE ,  TESCHENDORF HANS-JUERGEN ,  WICKE KARSTEN ,  DRESCHER KARLA

IPC: C07D239/26 ,  A61K31/505 ,  A61K31/506 ,  A61P25/16 ,  A61P25/24 ,  A61P25/26 ,  C07D239/38 ,  C07D239/46 ,  C07D239/56 ,  C07D239/60 ,  C07D401/00 ,  C07D401/12 ,  C07D

Abstract: The present invention relates to the use of pyrimidine compounds of the following formula:wherein R1, R2, R3, A, B and Ar have the meanings indicated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat disorders which respond to dopamine D3 ligands.

公开(公告)号：FI970150A

公开(公告)日：1997-01-14

申请号：FI970150

申请日：1997-01-14

Applicant: BASF AG

Inventor： HELLENDAHL BEATE ,  LANSKY ANNEGRET ,  MUNSCHAUER RAINER ,  BIALOJAN SIEGFRIED ,  UNGER LILIANE ,  TESCHENDORF HANS-JUERGEN ,  WICKE KARSTEN ,  DRESCHER KARLA

IPC: C07D239/26 ,  A61K31/505 ,  A61K31/506 ,  A61P25/16 ,  A61P25/24 ,  A61P25/26 ,  C07D239/38 ,  C07D239/46 ,  C07D239/56 ,  C07D239/60 ,  C07D401/00 ,  C07D401/12 ,  C07D

Abstract: The present invention relates to the use of pyrimidine compounds of the following formula:wherein R1, R2, R3, A, B and Ar have the meanings indicated in the description. The compounds according to the invention have a high affinity for the dopamine D3 receptor and can therefore be used to treat disorders which respond to dopamine D3 ligands.

公开(公告)号：NO964121L

公开(公告)日：1996-11-26

申请号：NO964121

申请日：1996-09-27

Applicant: BASF AG

Inventor： BAUMANN ERNST ,  VOGELBACHER UWE JOSEF ,  RHEINHEIMER JOACHIM ,  KLINGE DAGMAR ,  RIECHERS HARTMUT ,  KROGER BURKHARD ,  BIALOJAN SIEGFRIED ,  BOLLSCHWEILER CLAUS ,  WERNET WOLFGANG ,  UNGER LILIANE ,  RASCHACK MANFRED

IPC: A61K31/00 ,  C07D251/26 ,  A61K31/505 ,  A61K31/506 ,  A61K31/53 ,  A61P9/00 ,  A61P9/08 ,  A61P9/10 ,  A61P9/12 ,  A61P11/08 ,  A61P13/02 ,  A61P15/00 ,  A61P25/04 ,  A61P39/02 ,  C07D239/26 ,  C07D239/34 ,  C07D239/38 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  A61K

Abstract: PCT No. PCT/EP95/01099 Sec. 371 Date Sep. 30, 1996 Sec. 102(e) Date Sep. 30, 1996 PCT Filed Mar. 23, 1995 PCT Pub. No. WO95/26716 PCT Pub. Date Oct. 12, 1995A method of inhibiting endothelin receptors by administering to a patient a compound of the formula I I

公开(公告)号：ES2080326T3

公开(公告)日：1996-02-01

申请号：ES91912909

申请日：1991-07-19

Applicant: BASF AG

Inventor： BACH ALFRED ,  HILLEN HEINZ ,  BIALOJAN SIEGFRIED

IPC: A61K38/00 ,  A61K35/76 ,  A61K38/46 ,  A61P7/02 ,  A61P13/02 ,  A61P15/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/64 ,  C12N15/09 ,  C12N15/12 ,  C12N15/31 ,  C12N15/57

公开(公告)号：DK0540560T3

公开(公告)日：1995-12-27

申请号：DK91912909

申请日：1991-07-19

Applicant: BASF AG

Inventor： BIALOJAN SIEGFRIED ,  BACH ALFRED ,  HILLEN HEINZ

IPC: A61K38/00 ,  A61K35/76 ,  A61K38/46 ,  A61P7/02 ,  A61P13/02 ,  A61P15/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/64 ,  C12N15/09 ,  C12N15/12 ,  C12N15/31 ,  C12N15/57 ,  A61K37/54

公开(公告)号：MX9205978A

公开(公告)日：1993-04-01

申请号：MX9205978

申请日：1992-10-16

Applicant: BASF AG

Inventor： FRIEDRICH THOMAS ,  BIALOJAN SIEGFRIED ,  BOLLSCHWEILER CLAUS ,  KUENAST CHRISTOPH

IPC: A61K35/64 ,  A61K38/00 ,  A61K38/55 ,  A61P7/02 ,  C07K14/435 ,  C07K14/81 ,  C12N15/09 ,  C12N15/15 ,  C12P21/02 ,  C12R1/19 ,  C07K13/00

公开(公告)号：CA2098706A1

公开(公告)日：1992-06-23

申请号：CA2098706

申请日：1991-12-12

Applicant: BASF AG

Inventor： BACH ALFRED ,  UNGER LILIANE ,  BIALOJAN SIEGFRIED ,  SEEBURG PETER

IPC: A61K38/00 ,  C07K14/00 ,  C07K14/705 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N15/09 ,  C12N15/12 ,  C12N15/31 ,  C12P21/02 ,  C12Q1/02 ,  C12R1/91 ,  G01N33/554 ,  G01N33/566

Abstract: 2098706 9211362 PCTABS00014 The description relates to novel polypeptides which are 5HT1X receptors. The polypeptides are produced by genetic engineering.

公开(公告)号：CA2083286A1

公开(公告)日：1992-01-27

申请号：CA2083286

申请日：1991-07-19

Applicant: BASF AG

Inventor： BIALOJAN SIEGFRIED ,  HILLEN HEINZ ,  BACH ALFRED

IPC: A61K38/00 ,  A61K35/76 ,  A61K38/46 ,  A61P7/02 ,  A61P13/02 ,  A61P15/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/64 ,  C12N15/09 ,  C12N15/12 ,  C12N15/31 ,  C12N15/57 ,  A61K38/48

Abstract: Glycosylated, partially glycosylated and non-glycosylated polypeptides which have the amino-acid sequences indicated in the sequence listing and in which up to 10 amino-acid residues can be replaced by residues of other natural amino acids are described. The peptides are suitable for controlling diseases.