公开(公告)号：WO1998022567A1

公开(公告)日：1998-05-28

申请号：PCT/US1997020057

申请日：1997-11-03

Applicant: ALCON LABORATORIES, INC.

Inventor： ALCON LABORATORIES, INC. ,  VAN DUZEE, Barry, F. ,  STONE, Ralph, P. ,  ASGHARIAN, Bahram

IPC: C11D03/386

CPC classification number: C11D3/38663 ,  A61L12/142 ,  A61L12/145 ,  C11D3/0078

Abstract: Compositions containing an ophthalmically acceptable enzyme of high purity and integrity in a liquid medium and methods involving the use of these compositions for cleaning a contact lens, and in combination with an anti-microbial agent for the simultaneous cleaning and disinfecting of contact lens are disclosed.

Abstract translation: 公开了含有液体介质中高纯度和完整性的眼科可接受的酶的组合物和涉及使用这些组合物来清洁隐形眼镜的方法，以及与用于同时清洁和消毒隐形眼镜的抗微生物剂组合。

公开(公告)号：WO1998021182A3

公开(公告)日：1998-05-22

申请号：PCT/US1997020857

申请日：1997-11-07

Applicant: ALCON LABORATORIES, INC. ,  KLIMKO, Peter, G. ,  ZINKE, Paul, W.

Inventor： ALCON LABORATORIES, INC.

IPC: A61K31/557

公开(公告)号：WO1998019826A1

公开(公告)日：1998-05-14

申请号：PCT/US1997019881

申请日：1997-10-31

Applicant: ALCON LABORATORIES, INC.

Inventor： ALCON LABORATORIES, INC. ,  LEWELLEN, Kevin ,  SHEETS, John, W., Jr.

IPC: B24B31/00

CPC classification number: B24B13/0006 ,  A61F2/145 ,  A61F2/16 ,  B08B3/044 ,  B24B1/00 ,  B24B9/20 ,  B24B13/0025 ,  B24B31/00 ,  B24B31/02 ,  B24B31/06 ,  C09G1/02 ,  G02C7/04

Abstract: A method for polishing articles comprising soft acrylic materials is disclosed. The method includes a cryogenic polishing step and a cleaning step. In the polishing step, a receptacle is charged with polishing beads of various sizes, sodium bicarbonate, a swelling agent and the articles to be polished, for a period of time and at a rotation speed sufficient to remove surface irregularities. Following the polishing step, a receptacle is charged with (a) a cleaning slurry comprising cleaning beads of various sizes and (i) sodium hydroxide and water or (ii) alumina, a surfactant and a solvent and (b) the articles to be cleaned, for a period of time and at a rotation speed sufficient to clean the surface of the polished articles. Agitation is preferably accomplished by a tumbling machine.

Abstract translation: 公开了一种用于抛光包含柔软丙烯酸材料的制品的方法。 该方法包括低温​​抛光步骤和清洁步骤。 在抛光步骤中，在容器中装入各种尺寸的抛光珠，碳酸氢钠，溶胀剂和待抛光的物品一段时间，并以足以去除表面不规则的旋转速度。 在抛光步骤之后，向容器中装入（a）包括各种尺寸的清洁珠粒和（i）氢氧化钠和水或（ii）氧化铝，表面活性剂和溶剂的清洁浆料的清洁浆料和（b）待清洁的物品 一段时间并且以足以清洁抛光制品表面的旋转速度。 搅拌优选通过滚筒机实现。

公开(公告)号：WO1998014193A1

公开(公告)日：1998-04-09

申请号：PCT/US1997006410

申请日：1997-04-17

Applicant: ALCON LABORATORIES, INC.

Inventor： ALCON LABORATORIES, INC. ,  GAMACHE, Daniel, A. ,  YANNI, John, M.

IPC: A61K31/445

CPC classification number: A61K31/445

Abstract: Methods and compositions for treating ocular pain using a substance P antagonist are disclosed.

Abstract translation: 公开了使用物质P拮抗剂治疗眼痛的方法和组合物。

公开(公告)号：WO1998014148A1

公开(公告)日：1998-04-09

申请号：PCT/US1997015883

申请日：1997-09-09

Applicant: ALCON LABORATORIES, INC.

Inventor： ALCON LABORATORIES, INC. ,  BOUKHNY, Mikhail ,  CHON, James, Y.

IPC: A61F09/007

CPC classification number: A61F9/00745 ,  A61B2017/320072

Abstract: A cutting tip having an asymmetric, hydrodynamic channel that tightens the cutting tip during operation.

Abstract translation: 具有不对称流体动力通道的切割尖端，其在操作期间收紧切割尖端。

公开(公告)号：WO1997041844A1

公开(公告)日：1997-11-13

申请号：PCT/US1997005574

申请日：1997-04-03

Applicant: ALCON LABORATORIES, INC. ,  DOSHI, Rupa ,  CLARK, Abbot, F.

Inventor： ALCON LABORATORIES, INC.

IPC: A61K31/00

CPC classification number: A61K31/496 ,  A61K31/343 ,  A61K31/352

Abstract: The present invention is directed to compositions containing combinations of angiostatic compounds and methods for their use in preventing pathological neovascularization.

Abstract translation: 本发明涉及含有血管生成抑制化合物组合的组合物及其用于预防病理性新血管形成的方法。

公开(公告)号：WO1997038693A1

公开(公告)日：1997-10-23

申请号：PCT/US1997006107

申请日：1997-04-08

Applicant: ALCON LABORATORIES, INC. ,  YAMANOUCHI PHARMACEUTICAL CO., LTD. ,  MILLER, Steven, T. ,  HELLBERG, Mark, R. ,  YANNI, John, M.

Inventor： ALCON LABORATORIES, INC. ,  YAMANOUCHI PHARMACEUTICAL CO., LTD.

IPC: A61K31/44

CPC classification number: A61K9/0048 ,  A61K31/4422 ,  A61K31/443 ,  A61K31/4439 ,  Y10S514/912

Abstract: Compositions and methods for treating ocular allergic reactions are disclosed. In particular, the invention is directed to compounds which inhibit human conjunctival mast cell degranulation.

Abstract translation: 公开了用于治疗眼部过敏反应的组合物和方法。 特别地，本发明涉及抑制人结膜肥大细胞脱粒的化合物。

公开(公告)号：WO1997023226A1

公开(公告)日：1997-07-03

申请号：PCT/US1996018888

申请日：1996-11-25

Applicant: ALCON LABORATORIES, INC.

Inventor： ALCON LABORATORIES, INC. ,  DEAN, Thomas, Robert

IPC: A61K31/557

CPC classification number: A61K31/557 ,  A61K31/415 ,  A61K31/27 ,  A61K2300/00

Abstract: Methods for controlling glaucoma or ocular hypertension with combinations of DP-agonists and miotics are disclosed.

Abstract translation: 公开了用DP-激动剂和迷迭香剂组合控制青光眼或高眼压症的方法。

公开(公告)号：WO1997017331A1

公开(公告)日：1997-05-15

申请号：PCT/US1996015392

申请日：1996-09-26

Applicant: ALCON LABORATORIES, INC.

Inventor： ALCON LABORATORIES, INC. ,  YORK, Billie, M. ,  YANNI, John, M. ,  DUPRIEST, Mark, T.

IPC: C07D233/50

CPC classification number: C07D233/50 ,  Y10S514/913

Abstract: The present invention is directed to substantially pure apraclonidine of structure (I), compositions thereof and methods for controlling intraocular pressure.

Abstract translation: 本发明涉及结构（I）的基本上纯的阿普拉定，其组合物和用于控制眼内压的方法。

公开(公告)号：WO1997010236A1

公开(公告)日：1997-03-20

申请号：PCT/US1996011821

申请日：1996-07-17

Applicant: ALCON LABORATORIES, INC.

Inventor： ALCON LABORATORIES, INC. ,  HELLBERG, Mark, R. ,  DELGADO, Pete ,  NIXON, Jon, C.

IPC: C07D307/80

CPC classification number: C07D307/79 ,  C07D307/80 ,  C07D311/72 ,  Y10S514/914

Abstract: Compounds having anti-inflammatory and anti-oxydant activity are disclosed. The compounds are useful in preventing and treating inflammatory disorders through several mechanisms. Methods of treatment employing these properties of the compounds and corresponding pharmaceutical compositions are disclosed.

Abstract translation: 公开了具有抗炎和抗氧化活性的化合物。 该化合物可用于通过几种机制预防和治疗炎症性疾病。 公开了使用这些化合物和相应药物组合物性质的治疗方法。