公开(公告)号：DE3261426D1

公开(公告)日：1985-01-17

申请号：DE3261426

申请日：1982-03-31

Applicant: BASF AG

Inventor： WIERSDORFF WALTER-WIELANT DR ,  KROPP RUDOLF

IPC: C07D237/22

公开(公告)号：GR75519B

公开(公告)日：1984-07-26

申请号：GR820167448

申请日：1982-03-02

Applicant: BASF AG

Inventor： WALTER-WIERSDORF DR ,  KROPP RUDOLF

IPC: C07D237/22

公开(公告)号：DE3229215A1

公开(公告)日：1984-02-09

申请号：DE3229215

申请日：1982-08-05

Applicant: BASF AG

Inventor： KROPP RUDOLF

IPC: A61K31/435 ,  A61P9/00 ,  A61P25/00 ,  C07D471/04

Abstract: Salts of 1,2,3,4-tetrahydro- beta -carbolines of the formula I (I) where R is hydrogen, halogen, C1-C4-alkyl, C1-C4-alkoxy or trifluoromethyl, x is halogen and n is an integer from 2 to 5, and their preparation are described. The compounds are intermediates for the preparation of pharmacologically active substances.

公开(公告)号：DE3064073D1

公开(公告)日：1983-08-18

申请号：DE3064073

申请日：1980-02-14

Applicant: BASF AG

Inventor： KROPP RUDOLF ,  THOEMEL FRANK DR ,  NUERRENBACH AXEL DR ,  HOFFMANN WERNER DR ,  WENISCH FRANZ DR ,  FUCHS HARTWIG

IPC: C07C45/00 ,  C07C45/69 ,  C07C49/517 ,  C07C67/00 ,  C07D307/20 ,  C07D309/12 ,  C07D311/74 ,  C07D311/94

Abstract: The preparation of bicyclic enol-ethers (I) (I) (where n is from 3 to 12, and R1, R2 and R3 may be H or C1-C4-alkyl) by free radical adduct formation of CHR1 =CR2-CHR3-O-R4 (III)(where R4 is tert.-butyl, tetrahydrofuran-2-yl or tetrahydropyran-2-yl) with a cyclic ketone (IV) (IV) followed by acid-catalyzed cyclization, and novel compounds II (II) The compounds (I) and (II) are intermediates for the synthesis of musk-like fragrances.

公开(公告)号：DE2937836A1

公开(公告)日：1981-04-09

申请号：DE2937836

申请日：1979-09-19

Applicant: BASF AG

Inventor： KROPP RUDOLF ,  FISCHER MARTIN DIPL CHEM DR ,  HALBRITTER KLAUS DIPL CHEM DR

IPC: C07D307/30 ,  C07D307/32 ,  C07D307/33

Abstract: Preparation of 5-(2,2,2-trihaloethyl)-4,4-dialkyl-tetrahydro-furan-2-ones of the formula I (I) where R1 and R2 are each alkyl of 1 to 4 carbon atoms and X is halogen, by reacting a carboxylic acid amide of the formula II (II) where R3 and R4 are each alkyl of 1 to 4 carbon atoms, aralkyl of 7 to 9 carbon atoms or aryl of 6 to 10 carbon atoms or together with the nitrogen on which they are present as substituents form a 5-membered or 6-membered saturated ring which may contain a second hetero-atom, with a carbon tetrahalide of the formula III CX4 (III) to give an iminium salt of the formula IV (IV) and subsequently hydrolyzing this iminium salt; and novel iminium salts of the formula IV.

公开(公告)号：CA1042436A

公开(公告)日：1978-11-14

申请号：CA272966

申请日：1977-03-02

Applicant: BASF AG

Inventor： REICHENEDER FRANZ ,  KROPP RUDOLF ,  AMANN AUGUST ,  GIERTZ HUBERT

IPC: C07D237/10 ,  C07D237/20

Abstract: The present invention relates to new pyridazinium compounds of the general formula (I): (I) where R1 is hydrogen, R2 denotes -NH2, R3 is hydrogen, R4 denotes the radical -SR6, R6 being an alkyl of 1 to 12 carbon atoms, R5 is phenyl and Y.THETA. is an anion of a strong inorganic or organic acid; and their production. Particularly, the above compounds may be used for their circulatory and neuropharmacological effects as well as their analgesic and antiinflammatory effects on animals.

公开(公告)号：CH594634A5

公开(公告)日：1978-01-13

申请号：CH897376

申请日：1973-09-14

Applicant: BASF AG

Inventor： KROPP RUDOLF ,  REICHENEDER FRANZ DR ,  AMANN AUGUST DR ,  GIERTZ HUBERT DR

IPC: C07D237/06 ,  A01N43/58 ,  A61K31/50 ,  A61K31/535 ,  A61P7/10 ,  A61P9/00 ,  A61P9/02 ,  A61P25/00 ,  A61P25/02 ,  A61P25/04 ,  A61P25/24 ,  A61P25/26 ,  A61P29/00 ,  C07D237/20 ,  G03C1/12

Abstract: New pyridazinium compounds which can be used as intermediates and are of interest because of their pharmacological properties, and their production.

公开(公告)号：HU171228B

公开(公告)日：1977-12-28

申请号：HUBA003219

申请日：1975-02-28

Applicant: BASF AG

Inventor： FISCHER ADOLF ,  REICHENEDER FRANZ ,  KROPP RUDOLF

IPC: A01N47/38 ,  A01N43/56 ,  A01P13/00 ,  C07D231/18 ,  C07D231/56 ,  A01N9/00

公开(公告)号：CA990295A

公开(公告)日：1976-06-01

申请号：CA139352

申请日：1972-04-10

Applicant: BASF AG

Inventor： REICHENEDER FRANZ ,  KROPP RUDOLF ,  FISCHER ADOLF

IPC: A01N20060101 ,  C07D20060101 ,  C07D237/12 ,  C07D237/14 ,  C07D237/22

公开(公告)号：DE2139687A1

公开(公告)日：1973-02-15

申请号：DE2139687

申请日：1971-08-07

Applicant: BASF AG

Inventor： REICHENEDER FRANZ DR ,  KROPP RUDOLF ,  AMANN AUGUST DR ,  GIERTZ HUBERT PROF DR ,  SCHUSTER JOERG DR

IPC: A61K20060101 ,  A61K31/50 ,  C07D20060101 ,  A61K27/00