公开(公告)号：DE2210799A1

公开(公告)日：1973-09-20

申请号：DE2210799

申请日：1972-03-07

Applicant: BASF AG

Inventor： THIELE UWE DR ,  KOENIG HORST DR ,  FOEHLISCH BALDUR DR ,  AMANN AUGUST DR ,  GIERTZ HUBERT PROF DR ,  SCHUSTER JOERG DR

IPC: C07D493/08 ,  C07D5/04

Abstract: Hexahydro-benzocyclononenes of formula (I): (where X is O and R' and R2 are different; R' being OH and R2 being 1-6C alkoxy; 7-9C aralkoxy; amino carrying a 1-6 C alkyl, 3-6C cycloalkyl or 7-9C aralkyl residue; or hydrazino opt. substd. by aryl, or R' and R2 are identical, and are amino groups carrying a 1-6C alkyl, 3-6C cycloalkyl or 7-9C aralkyl residue; amino groups derived from a 5- to 7-membered secondary cyclic amine; or hydrazino opt. subst. by aryl; or X is imino and R' and R2 are each OH). (I) have anticonvulsant, sedative, analgesic or anti-inflammatory activity. (I; X= O, R'=R2=pyrrolidino) also has hypertensive activity.

公开(公告)号：DE2157454A1

公开(公告)日：1973-05-24

申请号：DE2157454

申请日：1971-11-19

Applicant: BASF AG

Inventor： HIMMELE WALTER DR ,  AQUILA WERNER DR ,  SIEGEL HARDO DR ,  AMANN AUGUST DR ,  GIERTZ HUBERT PROF DR

IPC: A01N45/02 ,  C07C67/00 ,  C07C209/00 ,  C07C209/26 ,  C07C211/31 ,  C07C211/44 ,  C07C213/00 ,  C07C217/06 ,  C07C229/52 ,  C07C241/00 ,  C07C243/18 ,  C07C275/24 ,  C07C301/00 ,  C07C303/40 ,  C07C311/03 ,  C07C311/16 ,  C07D207/26 ,  C07D207/267 ,  C07D213/38 ,  C07D295/02 ,  C07D295/03 ,  C07C87/00

公开(公告)号：DE2114097A1

公开(公告)日：1972-10-05

申请号：DE2114097

申请日：1971-03-24

Applicant: BASF AG

Inventor： AMANN AUGUST DR ,  KOENIG HORST DR ,  THIEME PETER DR

IPC: C07D277/42 ,  C07D277/46 ,  C07D277/48

Abstract: Title cpds. are of formula (I): (where R1 is lower alkyl, lower alkenyl, cycloalkyl, aryl or acyl; R2 and R3 are H or lower alkyl; R4 is H or 1-8C alkyl; or R3 + R4 can form a 4-6C spirocycloalkyl or 6-8C spirobicycloalkyl ring) and their salts, including the tautomeric 2-aminothiazoline form of (I; R2=H). They may be prepd. by (a) reacting R1NCS with R2NH-CR3R4-C triple bond CH to give R1NH-CS-NR2-CR3R4-C triple bond CH (II) and cyclising, or (b) reacting R1NH2 with SCN-CR3R4-C triple bond CH to give (IV; R2=H) and cyclising.

公开(公告)号：AT232002B

公开(公告)日：1964-02-25

申请号：AT155362

申请日：1962-02-23

Applicant: BASF AG

Inventor： AMANN AUGUST DR ,  JENTZSCH WOLFGANG DR ,  NEUBAUER GERALD DR

公开(公告)号：CH368159A

公开(公告)日：1963-03-31

申请号：CH5729558

申请日：1954-03-23

Applicant: BASF AG

Inventor： REPPE WALTER PROF DR ,  PASEDACH HEINRICH DR ,  DREHER ERICH DR ,  AMANN AUGUST DR

IPC: C07D295/096

公开(公告)号：DE2228259A1

公开(公告)日：1973-12-20

申请号：DE2228259

申请日：1972-06-09

Applicant: BASF AG

Inventor： THIEME PETER DR ,  KOENIG HORST DR ,  AMANN AUGUST DR

IPC: C07D277/42 ,  C07D513/04 ,  C07D91/42

Abstract: Process comprises reacting a cpd. (I) with a cpd. (II) and cyclising the resulting cpd. (III) to give the 2-methylene-2,3-dihydro-5-oxo- 5H-thiazolo-[21,31-b]quinazoline (IV): (where R1, R2, R3 are H or aliphatic gp., or R3 may be halogen, OH, CF3, alkoxy, alkylthio, NO2, CN, carboxyamido, sulphonic acid gp. or -NR4R4 where each R4 is H or aliphatic gp.). Cpds. (IV) are inflammation preventing agents, analgesics and sedatives, fungicides, bactericides and inters. for pharmaceuticals, dyes and pesticides.

公开(公告)号：DE2137276A1

公开(公告)日：1973-02-08

申请号：DE2137276

申请日：1971-07-26

Applicant: BASF AG

Inventor： HIMMELE WALTER DR ,  AQUILA WERNER DR ,  SIEGEL HARDO DR ,  AMANN AUGUST DR ,  GIERTZ HUBERT PROF DR

IPC: C07D295/02 ,  C07D295/03 ,  C07C87/42

Abstract: New 1-aminomethylindans and methods of producing them. The compounds are distinguished by their pharmacological effectiveness, particularly by their actions of lowering blood pressure and inhibiting inflammation and by their parasympathicolytic and central nervous system stimulating effects.

公开(公告)号：DK93020C

公开(公告)日：1962-03-19

申请号：DK454258

申请日：1958-12-12

Applicant: BASF AG

Inventor： AMANN AUGUST DR ,  BINDING KEMILABORANT JOHANNA ,  FRIEDRICH HERBERT DR

IPC: C07D20060101 ,  C07D

公开(公告)号：CH353354A

公开(公告)日：1961-04-15

申请号：CH353354D

申请日：1956-08-23

Applicant: BASF AG

Inventor： SCHLICHTING OTTO DR ,  PACHALY HEINZ DR ,  WESTPHAL FRANZ DR ,  AMANN AUGUST DR

公开(公告)号：CH347828A

公开(公告)日：1960-07-31

申请号：CH347828D

申请日：1956-08-20

Applicant: BASF AG

Inventor： SCHLICHTING OTTO DR ,  PACHALY HEINZ DR ,  AMANN AUGUST DR