中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

222 records (took 0.025 seconds)

    113.
    发明专利
    未知

    公开(公告)号：DE102004061846A1

    公开(公告)日：2006-07-13

    申请号：DE102004061846

    申请日：2004-12-22

    Applicant: BASF AG

    Inventor： HAEFNER STEFAN ,  SCHROEDER HARTWIG ,  ZELDER OSKAR ,  KLOPPROGGE CORINNA ,  HEROLD ANDREA

    IPC: C12N15/11 ,  C12N1/21

    Abstract: An expression unit (A) that contains several promoters is new. A new expression unit (A) comprises several promoters and includes, in the 5' to 3' direction the sequence module (I). 5'-P 1-(A x-P x) n-A y-P y-3' (I) n = integer 0-10; A x and A y = same or different chemical bonds or nucleic acid linker sequences; P 1, P x and P y = same or different promoter sequences, containing at least one RNA-polymerase binding region, and at least P y also includes a ribosome-binding, 3'-terminal segment. Independent claims are also included for: (1) an expression cassette (EC) that contains, in the 5' to 3' direction, the sequence module (II); (2) vector that contains at least one EC; (3) a genetically modified microorganism (GMO) transfected with the vector of (2) or containing EC; and (4) method for preparing biosynthetic products (X) by culturing GMO. 5'-P 1-(A x-P x) n-A y-P y-G-3' (II) G : at least one nucleic acid coding sequence functionally linked to the 5'-upstream regulatory sequence.

    116.
    发明专利
    未知

    公开(公告)号：BR0317507A

    公开(公告)日：2005-11-16

    申请号：BR0317507

    申请日：2003-12-19

    Applicant: BASF AG

    Inventor： KLOPPROGGE CORINNA ,  ZELDER OSKAR ,  KROEGER BURKHARD ,  SCHROEDER HARTWIG ,  HOFNER STEFAN ,  LIEBL WOLFGANG

    IPC: C12P13/04

    Abstract: The invention relates to a method for producing an amino acid comprising culturing a microorganism of the genus Corynebacterium or Brevibacterium wherein said microorganism is partially or completely deficient in at least one of the gene loci of the the group which is formed by otsAB, treZ and treS, and subsequent isolation of the amino acid from the culture medium.

    117.
    发明专利
    未知

    公开(公告)号：DE10359660A1

    公开(公告)日：2005-07-28

    申请号：DE10359660

    申请日：2003-12-18

    Applicant: BASF AG

    Inventor： KROEGER BURKHARD ,  ZELDER OSKAR ,  KLOPPROGGE CORINNA ,  SCHROEDER HARTWIG ,  HAEFNER STEFAN

    IPC: C12N9/02 ,  C12N15/77 ,  C12N15/63 ,  C12N15/67 ,  C12N1/00 ,  C12P1/00 ,  C12P13/08 ,  C12P13/12

    Abstract: Use of a nucleic acid (I) with promoter activity for transcribing genes, where (I) is (a) a 173 nucleotide sequence (SEQ ID No.:1); (b) a variant of (SEQ ID No.:1) with at least 90% identity and derived by substitution, insertion or deletion of nucleotides; (c) a sequence that hybridizes to (SEQ ID No.:1) under stringent conditions; or (d) a functionally equivalent fragment of (a)-(c), is new. Independent claims are also included for: (1) use of an expression unit (EU), containing (I) and functionally linked to a sequence (X) that ensures translation of RNA, for expressing genes; (2) (I), other than sequence (SEQ ID No.:1), i.e. (Ia), as new compounds; (3) EU that contain (Ia) linked to (X); (4) altering (or producing) the transcription rate of genes in a microorganism, relative to the wild type; (5) expression cassette (EC) comprising at least one EU of (SEQ ID No.:1), at least one other nucleic acid sequence (to be expressed) and optionally additional gene control elements, where at least the first two are linked and the sequence being expressed is heterologous with respect to EU; (6) expression vector (EV) that contains EC; (7) genetically modified microorganisms (GMO) having, for at least one gene, an altered (or induced) transcription rate, relative to the wild type; (8) preparing biosynthetic products by culturing GMO of (7); (9) use of the sequence gaaagga (SEQ ID No.:44) as a ribosome-binding site in expression units that provide expression of genes in Corynebacterium or Brevibacterium; (10) use of the sequences tgcaat (SEQ ID No.:42) and tatcatt (SEQ ID No.:43) as -10 regionS for expression of genes in Corynebacterium or Brevibacterium; and (11) expression units that contain sequences (SEQ ID No.:42) - (SEQ ID No.:44).

    PSOD EXPRESSION UNITS
    118.
    发明专利
    PSOD EXPRESSION UNITS 未知

    公开(公告)号：CA2549171A1

    公开(公告)日：2005-06-30

    申请号：CA2549171

    申请日：2004-12-16

    Applicant: BASF AG

    Inventor： KLOPPROGGE CORINNA ,  ZELDER OSKAR ,  HAEFNER STEFAN ,  KROEGER BURKHARD ,  SCHROEDER HARTWIG

    IPC: C12N15/77 ,  C12N1/21 ,  C12N9/02

    Abstract: The invention relates to the use of nucleic acid sequences for regulating ge ne transcription and expression, said novel promoters and expression units, methods for modifying or inducing the gene transcription rate and/or expression rate, expression cassettes containing said expression units, genetically modified microorganisms having a modified or induced transcripti on rate and/or expression rate, and methods for producing biosynthetic products by cultivating said genetically modified microorganisms.

Patent Agency Ranking