VERFAHREN ZUR HERSTELLUNG FLUORMETHYLSUBSTITUIERTER HETEROCYCLISCHER VERBINDUNGEN
    111.
    发明公开
    VERFAHREN ZUR HERSTELLUNG FLUORMETHYLSUBSTITUIERTER HETEROCYCLISCHER VERBINDUNGEN 审中-公开
    用于生产甲基FLUOR取代的杂环CONNECTIONS

    公开(公告)号:EP2121618A1

    公开(公告)日:2009-11-25

    申请号:EP07858009.9

    申请日:2007-12-20

    Applicant: BASF SE

    CPC classification number: C07D231/14

    Abstract: The present invention relates to a process for the preparation of fluoromethyl-substituted heterocyclic compounds of the general formula (I), in which R1 is H or F; R2 is a group -[A-O]m-R3, in which A is C2-C4-alkanediyl, R3 is C1-C4-alkyl and m is 1 or 2, by reaction of the corresponding chloromethyl-substituted compounds (II) in the presence of fluorinating agents, to processes for preparing the chloromethyl-substituted compounds (II), to processes for preparing amides of the general formula (IV), and to compounds of the general formulae (I) and (II).

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