公开(公告)号：US20240204475A1

公开(公告)日：2024-06-20

申请号：US18530590

申请日：2023-12-06

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Hansuek LEE ,  In Hwan DO ,  Daewon SUK ,  Jae Hoon LEE ,  Hyun-Gue HONG ,  Dai-Hyuk YU

IPC: H01S3/30 ,  H01S3/094 ,  H01S3/131 ,  H01S3/067 ,  H01S3/16

CPC classification number: H01S3/302 ,  H01S3/094053 ,  H01S3/1312 ,  H01S3/06716 ,  H01S3/1608 ,  H01S2301/085

Abstract: An apparatus for generating optical frequency combs and solitons includes a pump laser configured to output a pump signal with a pump wavelength, and a resonator module connected to the pump laser through an optical path and including a resonator and a waveguide structured to adjust a degree of coupling. The resonator generates at least one of pump combs at the pump wavelength, Raman combs at a Raman scattering wavelength or solitons, through different nonlinear phenomena.

公开(公告)号：US12011223B2

公开(公告)日：2024-06-18

申请号：US17280284

申请日：2019-10-08

Applicant: Korea Research Institute of Standards and Science

Inventor： Sang Won Lee ,  Il Doh ,  Hyunji Lee

IPC: A61B3/00 ,  A61B3/10 ,  A61B3/12

CPC classification number: A61B3/0025 ,  A61B3/102 ,  A61B3/1241

Abstract: The present invention relates to an eye phantom for evaluating a retinal angiography image, and a manufacturing method therefor. A purpose of the present invention is to provide an eye phantom for evaluating a retinal angiography image, capable of simulating even the vascular structure and blood flow of a retina so as to be more similar to an actual retinal structure than a conventional eye phantom; and a manufacturing method therefor. More specifically, a purpose of the present invention is to provide an eye phantom for evaluating a retinal angiography image, including various shapes of fine fluid channel structures corresponding to the vascular structure formed in an actual retina; and a manufacturing method therefor.

公开(公告)号：US20240168106A1

公开(公告)日：2024-05-23

申请号：US17991087

申请日：2022-11-21

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Jeong Hyun Shim ,  Sang Won Oh ,  Ki Woong Kim ,  Kwang Geol Lee

IPC: G01R33/032 ,  G01R33/00

CPC classification number: G01R33/032 ,  G01R33/0017 ,  G01R33/0082

Abstract: Disclosed is a method and apparatus for measuring magnetic field and/or temperature using a diamond nitrogen-vacancy center sensor, and a measuring apparatus based on a diamond nitrogen-vacancy center (DNV) sensor may include: a diamond nitrogen-vacancy center sensor; a frequency synthesizer for generating a first reference signal and a second reference signal; a first microwave generator for generating a first microwave that is frequency modulated according to the first reference signal and causes a first spin transition in the diamond nitrogen-vacancy center sensor; a second microwave generator for generating a second microwave that is frequency modulated according to the second reference signal and causes a second spin transition in the diamond nitrogen-vacancy center sensor; a laser irradiator for applying a laser to excite the spin state of the diamond nitrogen-vacancy center sensor; a power amplifier for combining and amplifying the first microwave and the second microwave to apply to the diamond nitrogen-vacancy center sensor; a detector for detecting a fluorescence signal output from the diamond nitrogen-vacancy center sensor; a reference detector for measuring power of the laser; a differential circuit for outputting the difference between an output signal of the detector and an output signal of the reference detector; a first lock-in amplifier for outputting a result of comparing an output of the differential circuit with the first reference signal, and a second lock-in amplifier for outputting a result of comparing an output of the differential circuit with the second reference signal. Using the apparatus, it is possible to remove an influence of the temperature when measuring the magnetic field, and remove an influence of a change in the magnetic field when measuring the temperature, thereby enabling more precise measurement.

公开(公告)号：US20240053302A1

公开(公告)日：2024-02-15

申请号：US17776909

申请日：2022-04-04

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Jong Moon HA ,  Won Jae CHOI ,  Hong Min SEUNG

IPC: G01N29/44 ,  G01N29/024 ,  G06N3/0455 ,  G06N3/08

CPC classification number: G01N29/4472 ,  G01N29/024 ,  G06N3/0455 ,  G06N3/08 ,  G01N2291/101 ,  G01N2291/011 ,  G01N2291/023 ,  G01N2291/0289

Abstract: An ultrasonic NDT method and system, which can extract and analyze a defect signal even when a signal reflected from a defect interferes with a unique initial pulse of an ultrasonic transducer or a signal reflected from the surface of a test object, and an autoencoder-based prediction model training method used therefor. The method may include acquiring a measured signal by transmitting an ultrasonic wave to a test object and receiving an ultrasonic wave reflected from the test object; inputting the measured signal to an autoencoder-based prediction model and predicting a reference signal which is to be expected to be measured from a test object with no defect; calculating a residual signal as the absolute value of a difference between the measured signal and the reference signal; and analyzing information on a defect contained in the test object by analyzing the residual signal.

公开(公告)号：US20230360629A1

公开(公告)日：2023-11-09

申请号：US17777465

申请日：2020-11-11

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Won Jae CHOI ,  Miso KIM ,  Jae Yub HYUN

IPC: G10K11/30 ,  G10K11/24 ,  G02B1/00

CPC classification number: G10K11/30 ,  G02B1/005 ,  G10K11/24

Abstract: A gradient-index phononic crystal flat lens which controls the behavior of an acoustic wave having a designated frequency. The gradient-index phononic crystal flat lens may include one or more super cells each having a plurality of layers stacked in a vertical direction according to a target gradient index profile, wherein each of the layers is composed of an aggregate in which unit cells having scatterers formed with the same size in the centers thereof are arranged in a horizontal direction. The one or more super cells may each include a divider provided between the neighboring layers, and configured to force the acoustic wave to propagate in the horizontal direction within the gradient-index phononic crystal flat lens.

公开(公告)号：US11810701B2

公开(公告)日：2023-11-07

申请号：US17318613

申请日：2021-05-12

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Chan Yong Hwang ,  Kyoung Woong Moon ,  Seung Mo Yang ,  Chang Soo Kim

IPC: H01F10/32 ,  H01F7/06 ,  G06T7/00 ,  G06F18/22

CPC classification number: H01F10/324 ,  G06F18/22 ,  G06T7/001 ,  H01F7/064 ,  G06T2207/30108

Abstract: The present disclosure relates to a device and method for forming skyrmion in a magnetic thin film. A skyrmion forming method comprises aligning the surface of the magnetic thin film and a horizontal magnetic field to be applied to the magnetic thin film and applying the horizontal magnetic field and a vertical magnetic field to the magnetic thin film. Accordingly, it is possible to form the bubble skyrmion easily even in the case of a wide width of a stripe formed on the magnetic thin film.

公开(公告)号：US11719624B2

公开(公告)日：2023-08-08

申请号：US16464792

申请日：2016-12-15

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Hyun Mo Cho ,  Yong Jai Cho ,  Won Chegal

IPC: G01N21/05 ,  B01L3/00 ,  G01N21/21 ,  G01N33/543 ,  G01N21/03

CPC classification number: G01N21/05 ,  B01L3/502715 ,  G01N21/21 ,  G01N33/54366 ,  B01L2300/0654 ,  B01L2300/0663 ,  G01N21/211 ,  G01N2021/0378 ,  G01N2021/052

Abstract: The present invention relates to a liquid immersion micro-channel measurement device and measurement method which are based on trapezoidal incident structure prism incident-type silicon, and according to one embodiment of the present invention, the liquid immersion micro-channel measurement device based on trapezoidal incident structure prism incident-type silicon comprises: a micro-channel structure including a support and at least one micro-channel, which is formed on the support and has a sample detection layer to which a first bioadhesive material for detecting a first sample is fixed; a quadrangular pyramid-shaped prism formed on the upper part of the micro-channel structure; a sample injection unit for injecting, into the micro-channel, a buffer solution containing the first sample; a polarized light generation unit for emitting incident light polarized through the prism on the micro-channel at an incident angle that satisfies a p-wave non-reflection condition; and a polarized light detection unit for detecting, from the polarized incident light, a polarization change in a first refection light reflected from the sample detection layer, wherein the prism completely reflects, from the polarized incident light incident on the prism, on an upper boundary surface of the prism, second reflection light reflected from a lower boundary surface of the prism and a boundary surface of the buffer solution injected into the micro-channel.

公开(公告)号：US11592441B2

公开(公告)日：2023-02-28

申请号：US16216306

申请日：2018-12-11

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE ,  FOUNDATION FOR RESEARCH AND BUSINESS, SEOUL NATIONAL UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Tae Geol Lee ,  Hee Kyung Na ,  Jung Sub Wi ,  Jong G. OK

IPC: G01N33/543 ,  G01N21/552 ,  G01N21/77

Abstract: Provided is a nanoplasmonic sensor and a kit for biomolecule analysis, and a method of analyzing a biomolecule using the same. The method includes: providing the nanoplasmonic sensor including a dielectric grating extending in one direction, and a metal structure disposed to cover an upper surface and a side surface of the dielectric grating and have at least one bent portion; immobilizing a first probe molecule on a surface of the metal structure; hybridizing an analyte with the first probe molecule by introducing the analyte having a base sequence complementary to the first probe molecule; binding a second probe molecule that is hybridized with the first probe molecule to the analyte; binding an enzyme to the second probe molecule; introducing a substrate that reacts with the enzyme to produce a precipitate by an enzymatic reaction; and measuring localized surface plasmon resonance in the metal structure.

公开(公告)号：US20220285035A1

公开(公告)日：2022-09-08

申请号：US17689654

申请日：2022-03-08

Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE ,  KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Jae Hak YU ,  Se Jin PARK ,  Soon Hyun KWON ,  Nae Soo KIM ,  Da Mee KIM ,  Cheol Sig PYO ,  Seung Hee Hong

IPC: G16H50/70 ,  G16H50/20 ,  G16H50/30 ,  A61B5/00

Abstract: The present invention relates to a device and method of predicting disease by using elderly cohort data, and more particularly, to a device and method of predicting disease by using elderly cohort data and an elderly disease prediction model applied thereto, which may predict an outbreak possibility of an elderly disease including cerebral stroke by using cohort data of 60 or more-year-old persons.

公开(公告)号：US11435226B2

公开(公告)日：2022-09-06

申请号：US16403382

申请日：2019-05-03

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Kee-Suk Hong ,  Dong-Hoon Lee ,  Seongchong Park ,  Jisoo Hwang

IPC: G01J1/42 ,  G06N10/00 ,  G01J1/16 ,  G01J3/42

Abstract: Provided are an apparatus and method for measuring quantum efficiency of a detector using a single pulse laser. Quantum efficiency of the measurement target detector may be measured from 420 nm to 1600 nm having uncertainty of 2% to 4% (K=2) by comparing the reference detector and the measurement target detector significantly different in sensitivity using a single laser pulse as a spectral light source. Also, it is possible to directly compare the two detectors with a significant difference in sensitivity through a very simple setup that causes a portion of a laser pulse output from a light source part to be absorbed by the reference detector and the laser pulse reflected from the reference detector to be irradiated to the measurement target detector.