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公开(公告)号:BR9305090A
公开(公告)日:1995-08-08
申请号:BR9305090
申请日:1993-12-16
Applicant: BASF AG
Inventor: STEINER GERD , UNGER LILIANE , BEHL BERTHOLD , TESCHENDORF HANS-JUERGEN
IPC: A61K31/40 , C07D209/94
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公开(公告)号:PL301485A1
公开(公告)日:1995-06-26
申请号:PL30148593
申请日:1993-12-14
Applicant: BASF AG
Inventor: UNGER LILIANE , STEINER GERD , BEHL BERTHOLD , TESCHENDORF HANS-JUERGEN , MUNSCHAUER RAINER
IPC: C07D403/02
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公开(公告)号:ZA9309226B
公开(公告)日:1995-06-09
申请号:ZA9309226
申请日:1993-12-09
Applicant: BASF AG
Inventor: STINER GERD , UNGER LILIANE , BEHL BERTHOLD , TESCHENDORF HANS-JUERGEN
IPC: A61K20060101 , C07D20060101 , A61K , C07D
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144.
公开(公告)号:FI88038C
公开(公告)日:1993-03-25
申请号:FI882388
申请日:1988-05-20
Applicant: BASF AG
Inventor: STEINER GERD , PFISTER JUERGEN , TESCHENDORF HANS-JUERGEN , UNGER LILIANE , BINDER RUDOLF
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公开(公告)号:CA2098706A1
公开(公告)日:1992-06-23
申请号:CA2098706
申请日:1991-12-12
Applicant: BASF AG
Inventor: BACH ALFRED , UNGER LILIANE , BIALOJAN SIEGFRIED , SEEBURG PETER
IPC: A61K38/00 , C07K14/00 , C07K14/705 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12N15/31 , C12P21/02 , C12Q1/02 , C12R1/91 , G01N33/554 , G01N33/566
Abstract: 2098706 9211362 PCTABS00014 The description relates to novel polypeptides which are 5HT1X receptors. The polypeptides are produced by genetic engineering.
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146.
公开(公告)号:ZA8709280B
公开(公告)日:1989-08-30
申请号:ZA8709280
申请日:1987-12-10
Applicant: BASF AG
Inventor: SEITZ WERNER , WERNER SEITZ , UNGER LILIANE , LILIANE UNGER , RASCHACK MANFRED , MANFRED RASCHACK , BALDINGER VERENA , VERENA BALDINGER , RUEBSAMEN KLAUS , KLAUS RUEBSAMEN , GRIES JOSEF , JOSEF GRIES
IPC: A61K31/275 , A61K31/335 , A61K31/357 , A61K31/36 , A61P1/04 , A61P3/00 , A61P9/00 , A61P11/00 , A61P43/00 , C07C67/00 , C07C253/00 , C07C253/30 , C07C255/32 , C07C255/35 , C07C255/42 , C07C255/53 , C07C255/58 , C07D317/50 , C07D317/60 , C07D319/08 , C07D319/18 , C07D321/00 , C07C , A61K , C07D
CPC classification number: C07C255/00 , C07D317/60 , C07D319/08
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公开(公告)号:FI882389A
公开(公告)日:1988-11-22
申请号:FI882389
申请日:1988-05-20
Applicant: BASF AG
Inventor: STEINER GERD , TESCHENDORF HANS-JUERGEN , UNGER LILIANE , BINDER RUDOLF
Abstract: Compounds of the formula I where R1, R2, R3 and A have the meanings stated in the specification, as well as the use thereof for controlling diseases, are described.
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148.
公开(公告)号:AU8240387A
公开(公告)日:1988-06-16
申请号:AU8240387
申请日:1987-12-10
Applicant: BASF AG
Inventor: SEITZ WERNER , UNGER LILIANE , RASCHACK MANFRED , BALDINGER VERENA , RUEBSAMEN KLAUS , GRIES JOSEF
IPC: A61K31/275 , A61K31/335 , A61K31/357 , A61K31/36 , A61P1/04 , A61P3/00 , A61P9/00 , A61P11/00 , A61P43/00 , C07C67/00 , C07C253/00 , C07C253/30 , C07C255/32 , C07C255/33 , C07C255/35 , C07C255/37 , C07C255/42 , C07C255/53 , C07C255/58 , C07D317/50 , C07D317/60 , C07D319/08 , C07D319/18 , C07D321/00 , C07C121/80 , C07C121/78
Abstract: Basic-substituted phenylacetonitriles of the formula I … … in which… R to R and n have the meaning given in the description, are suitable for combating diseases.
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公开(公告)号:DE19533023B4
公开(公告)日:2007-05-16
申请号:DE19533023
申请日:1995-09-07
Applicant: BASF AG
Inventor: RIECHERS HARTMUT , KLINGE DAGMAR , AMBERG WILHELM , KLING ANDREAS , MUELLER STEFAN , BAUMANN ERNST , RHEINHEIMER JOACHIM , VOGELBACHER UWE JOSEF , WERNET WOLFGANG , UNGER LILIANE , RASCHACK MANFRED
IPC: C07D239/60 , C07D251/30 , A61K31/41 , A61K31/505 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/08 , A61P13/02 , A61P15/00 , A61P25/04 , C07D239/00 , C07D239/26 , C07D239/28 , C07D239/34 , C07D239/38 , C07D239/70 , C07D239/96 , C07D251/12 , C07D251/52 , C07D257/02 , C07D309/00 , C07D403/06 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D487/04 , C07D491/04 , C07D491/044 , C07D491/048 , C07D495/04
Abstract: Heterocyclyl-substd. propanoic acids and their derivs., of formula (I), are new. R = formyl, tetrazolyl, nitrile, COOH or a gp. that can be hydrolysed to COOH; X = N or CR14; R2 = H, OH, NH2, alkylamino, dialkylamino, halo, alkyl, haloalkyl, alkoxy, haloalkoxy or alkylthio; R14 = H or 1-5 C alkyl; R3 = R2 or alkoxyimino; or CR3 + CR14 = 5 or 6 membered alkylene or alkenyl ring (opt. substd. by 1-2 alkyl) in which a methylene can be replaced by O, S, NH or alkylamino; R4, R5 = phenyl or naphthyl (both opt. substd. by one or more halo, NO2, CN, OH, alkyl, haloalkyl, alkoxy, haloalkyloxy, phenoxy, alkylthio, NH2, alkylamine or dialkylamino) or 3-7 C cycloalkyl; or the phenyl or naphthyl gps. are opt. bonded at the O- position (by a bond, CH2, O, S, SO2, ethylene, ethenylene or opt. alkylated amino); R6 = H, 1-8 C alkyl, 2-6 C alkenyl, 3-6 C alkynyl, 3-8 C cycloalkyl (all opt. substd. by 1 or more halo, NO2, CN, alkoxy 3-6 C alkenyloxy, 3-6 C alkynyloxy, alkylthio, haloalkoxy, alkylcarbonyl, alkoxycarbonyl, 3-8 C alkylcarbonylalkyl, alkylamino, dialkylamino, phenyl, Ph or OPh), Ar or Het; Y = S, O or bond; Q = S, O, SO, SO2 or bond; Ph = substd. phenyl, where substits. are halo, NO2, CN, alkyl, haloalkyl, alkoxy, haloalkoxy or alkylthio; Ar = phenyl or naphthyl (both opt. substd. by 1 or more halo, NO2, CN, OH, NH2, alkylamino, dialkylamino or OCH2CH2O); Het = 5 or 6 membered heteroaromatic with 1-3 N atoms and/or one S or O (opt. substd. by 1-4 halo and/or 1 or 2 alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, phenyl, phenoxy or phenyl carbonyl (where the phenyl is opt. substd. by 1-5 halo and/or 1-3 alkyl, haloalkyl, alkoxy, haloalkoxy and/or alkylthio)); alkyl and alkoxy have 1-4 C unless otherwise stated; provided that R6 is not H when Q = bond.
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公开(公告)号:BG65029B1
公开(公告)日:2006-12-29
申请号:BG10405600
申请日:2000-01-04
Applicant: BASF AG
Inventor: STARCK DOROTHEA , BLANK STEFAN , TREIBER HANS-JOERG , UNGER LILIANE , NEUMANN-SCHULTZ BARBARA , LE BRIS THEOPHILE-MARIE , TESCHENDORF HANS-JUERGEN , WICKE KARSTEN
IPC: C07D249/12 , A61K31/33 , A61K31/41 , A61K31/4196 , A61K31/454 , A61K31/506 , A61K31/53 , A61K31/551 , A61P25/00 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P43/00 , C07D249/08 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
Abstract: The compounds have high dopamine-D-receptor activity and can be used for the treatment of diseases dependent on dopamine-D3-ligands. The triazole compounds have the formula where Ar1, A, B and Ar2 have the meanings listed in the description.
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